2-(5-Bromo-2-pyridylazo)-5-(diethylamino)phenol | 14337-53-2

• 物质功能分类: 生物化工 - 生化试剂
• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-(5-Bromo-2-pyridylazo)-5-(diethylamino)phenol
• 英文别名: 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol
• CAS: 14337-53-2
• 化学式: C₁₅H₁₇BrN₄O
• 分子量: 349.23
• InChiKey: HNVCXDAVEHOIBP-VHEBQXMUSA-N

物化性质

• 熔点：
  155-160 °C
• 沸点：
  511.1±50.0 °C(Predicted)
• 密度：
  1.39±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.81
• 重原子数：
  21.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  61.08
• 氢给体数：
  1.0
• 氢受体数：
  5.0

安全信息

• 安全说明：
  S22,S24/25
• 海关编码：
  2933399090
• WGK Germany：
  3
• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

制备方法与用途

化学性质
暗橙红色结晶或粉末。熔点为157-158℃（亦可表示为151-152℃）。其能溶于乙醇、丙酮和乙酸，但不溶于水。

用途
作为分析试剂使用，并可用作显色剂，用于镉(Cd)和镍(Ni)的比色测定。

生产方法
由2-氨基吡啶经溴化生成5-溴-2-氨基吡啶，再经重氮化得到5-溴-2-氨基吡啶重氮盐，最后通过偶合反应制得成品。

反应信息

• 作为反应物：
  描述：

  (E)-1-(3-bromopropyl)-2-((4-(dimethylamino)phenyl)diazenyl)pyridin-1-ium bromide 、 2-(5-Bromo-2-pyridylazo)-5-(diethylamino)phenol 以 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) 为溶剂， 反应 30.0h， 生成 5-bromo-2-{(E)-[4-(diethylamino)-2-hydroxyphenyl]diazenyl}-1-[3-(2-{(E)-[4-(dimethylamino)phenyl]diazenyl}pyridinium-1-yl)propyl]pyridinium dibromide
  参考文献：
  名称：

  Dissymmetrical diazo compounds comprising 2-pyridinium group and a cationic or non-cationic linker, compositions comprising them, method for coloring, and device

  摘要：

  本文公开了一种包含2-吡啶基团和阳离子或非阳离子连接物的不对称阳离子重氮化合物。本文还公开了包含此类化合物作为直接染料的染料组合物，以及适用于染色角蛋白纤维的介质。本文还公开了一种染色角蛋白纤维的方法，包括将角蛋白纤维与此类染料组合物接触。此外，还公开了一种包含多个隔室的装置。

  公开号：

  US20060149044A1

文献信息

• METHOD OF ASSAYING METAL PRESENT IN BIOLOGICAL SPECIMEN AND REAGENT THEREFOR
  申请人：IATRON LABORATORIES, INC.

  公开号：EP0592674A1

  公开（公告）日：1994-04-20

  A method of assaying trace metals present in a biological specimen at high accuracy and a reagent therefor. The assaying method comprises adding a metal other than the target metal to an assaying system to thereby liberate the target metal from the substance which is coexistent in the specimen and bonded to the target metal. The assaying reagent contains a metal other than the target metal to liberate the target metal from the substance which is coexistent in the specimen and bonded to the target metal.

  一种高精度测定生物样本中痕量金属的方法及其试剂。化验方法包括在化验系统中加入目标金属以外的金属，从而将目标金属从试样中与目标金属结合的物质中分离出来。化验试剂含有目标金属以外的一种金属，可将目标金属从试样中共存并与目标金属结合的物质中释放出来。
• IMAGE DIAGNOSIS PROBE BASED ON SUBSTITUTED AZOBENZENE OR ANALOGUE THEREOF FOR DISEASE ATTRIBUTABLE TO AMYLOID ACCUMULATION AND COMPOSITION FOR IMAGE DIAGNOSIS CONTAINING THE SAME
  申请人：BF Research Institute, Inc.

  公开号：EP1266884A1

  公开（公告）日：2002-12-18

  A compound represented by the formula (I):         (R1)m―A―X-----Y―B―(R2)n     (I) or a salt or a solvate thereof; and a composition and a kit both containing any of these. In said formula I, X represents CH, Sulfur, or nitrogen; Y represents CH, sulfur or nitrogen, or absent; ----- means a single bond or a double bond; A and B each independently represents a benzene ring or six-membered heterocyclic containing one or two atoms of nitrogen, oxygen, or sulfur; and R1 and R2 represent one to seven substituents of ring A and ring B, respectively.

  式 (I) 所代表的化合物： (R1)m-A-X-----Y-B-(R2)n (I) 或其盐或溶解物；以及含有其中任何一种的组合物和试剂盒。在所述式 I 中，X 代表 CH、硫或氮；Y 代表 CH、硫或氮，或不存在；----- 指单键或双键；A 和 B 各自独立地代表苯环或含有一个或两个氮、氧或硫原子的六元杂环；R1 和 R2 分别代表环 A 和环 B 的一至七个取代基。
• Ozone gas sensing element, detection apparatus, and measurement method
  申请人：Nippon Telegraph and Telephone Corporation

  公开号：EP1394541A2

  公开（公告）日：2004-03-03

  A sensing element in which a dye that changes in the light absorption characteristic of the visible region upon reaction with ozone gas is deposited in the pores of a porous material is prepared. A change in dye before and after exposing the sensing element to a measurement environment for a predetermined time is measured. The ozone gas amount in measurement target air is measured on the basis of the change in dye.

  制备了一种传感元件，其中在多孔材料的孔隙中沉积了一种染料，该染料在与臭氧气体反应时会改变可见光区的光吸收特性。在将传感元件暴露于测量环境中预定时间前后，测量染料的变化。根据染料的变化测量目标空气中的臭氧气体量。
• DRY TEST INSTRUMENT, METHOD OF MEASURING METAL AND METHOD OF PRODUCING DRY TEST INSTRUMENT
  申请人：ARKRAY, Inc.

  公开号：EP2261656A1

  公开（公告）日：2010-12-15

  The present invention provides a dry testing tool with which a metal in the various types of samples such as biological samples, food, and the like can be measured very easily, rapidly, high sensitively, and specifically by a simple colorimetric method and a method for measuring the metal. The dry testing tool of the present invention is a dry testing tool for measuring a metal in a sample, including a porous support and a chelate dye, wherein the chelate dye is bound to the porous support by a hydrophobic bond. The measuring method of the present invention is a method for measuring a metal in a sample, including the steps of: forming a composite of the chelate dye and the metal in the sample by supplying the sample to the porous support to which a chelate dye is bound by a hydrophobic bond; and detecting the metal in the sample using a developed color of the composite.

  本发明提供了一种干法测试工具，利用这种工具可以非常方便、快速、高灵敏度地测量各种类型样品（如生物样品、食品等）中的金属，并通过一种简单的比色法和一种测量金属的方法进行特异性测量。本发明的干法检测工具是一种测量样品中金属含量的干法检测工具，包括多孔支架和螯合染料，其中螯合染料通过疏水键与多孔支架结合。本发明的测量方法是一种测量样品中金属的方法，包括以下步骤：通过将样品提供给多孔支架，形成螯合染料和样品中金属的复合体，螯合染料通过疏水键结合在多孔支架上；利用复合体的显色检测样品中的金属。
• Optical sensors for downhole tools and related systems and methods
  申请人：Baker Hughes Incorporated

  公开号：US10025000B2

  公开（公告）日：2018-07-17

  A method of detecting at least one of an analyte or a condition of a fluid within a subterranean formation includes operably coupling a radiation source to at least one optical fiber coupled to a sensor having optically sensitive materials including at least one of chromophores, fluorophores, metal nanoparticles, or metal oxide nanoparticles dispersed within an optically transparent permeable matrix material. The sensor is contacted within a wellbore with a fluid and the fluid is passed through at least a portion of the sensor. Electromagnetic radiation is transmitted from the radiation source through at least one optical fiber to the sensor and at least one of an absorbance spectrum, an emission spectrum, a maximum absorption intensity, or a maximum emission intensity of electromagnetic radiation passing through the sensor after contacting at least some of the optically sensitive materials with the fluid is measured. Additional methods of determining a concentration of hydrogen sulfide in a fluid within a subterranean formation and related downhole optical sensor assemblies are disclosed.

  一种检测地下地层中的分析物或流体状况中至少一种的方法包括将辐射源与至少一根光纤可操作地耦合到传感器上，该传感器具有光学敏感材料，包括分散在光学透明渗透基质材料中的发色团、荧光团、金属纳米颗粒或金属氧化物纳米颗粒中的至少一种。传感器在井筒内与流体接触，流体至少穿过传感器的一部分。电磁辐射从辐射源通过至少一根光纤传输到传感器，测量至少部分光敏材料与流体接触后通过传感器的电磁辐射的吸收光谱、发射光谱、最大吸收强度或最大发射强度中的至少一个。此外，还公开了确定地下地层流体中硫化氢浓度的方法以及相关的井下光学传感器组件。

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