4-(2-Methylbut-3-enoxy)chromen-2-one | 1243085-89-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 4-(2-Methylbut-3-enoxy)chromen-2-one
• 英文别名: 4-(2-methylbut-3-enoxy)chromen-2-one
• CAS: 1243085-89-3
• 化学式: C₁₄H₁₄O₃
• 分子量: 230.263
• InChiKey: OYTJRVRRICDKHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(2-Methylbut-3-enoxy)chromen-2-one 以 苯 为溶剂， 反应 7.0h， 生成 、 (1S,10S,12R,13R)-13-methyl-8,15-dioxatetracyclo[8.5.0.01,12.02,7]pentadeca-2,4,6-trien-9-one
  参考文献：
  名称：

  LOPHTOR: a convenient flow-based photochemical reactor

  摘要：

  A flow-through photochemical reactor which enables facile control of irradiation time, temperature, and wavelength with minimal manual intervention is described. A series of intramolecular [2+2] enone cycloadditions were performed in this reactor in excellent yield and significantly shorter reaction time than conventional batch processes. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.05.119
• 作为产物：
  描述：

  4-羟基香豆素 、 4-溴-3-甲基-1-丁烯 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 4-(2-Methylbut-3-enoxy)chromen-2-one
  参考文献：
  名称：

  LOPHTOR: a convenient flow-based photochemical reactor

  摘要：

  A flow-through photochemical reactor which enables facile control of irradiation time, temperature, and wavelength with minimal manual intervention is described. A series of intramolecular [2+2] enone cycloadditions were performed in this reactor in excellent yield and significantly shorter reaction time than conventional batch processes. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.05.119

文献信息

• LOPHTOR: a convenient flow-based photochemical reactor
  作者：Anil Vasudevan、Clara Villamil、Jonathan Trumbull、Jeff Olson、David Sutherland、Jeff Pan、Stevan Djuric

  DOI：10.1016/j.tetlet.2010.05.119

  日期：2010.8

  A flow-through photochemical reactor which enables facile control of irradiation time, temperature, and wavelength with minimal manual intervention is described. A series of intramolecular [2+2] enone cycloadditions were performed in this reactor in excellent yield and significantly shorter reaction time than conventional batch processes. (C) 2010 Elsevier Ltd. All rights reserved.