ethyl 1-benzyl-2-(diethoxymethyl)pyrrolidine-2-carboxylate | 1374987-44-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethyl 1-benzyl-2-(diethoxymethyl)pyrrolidine-2-carboxylate
• CAS: 1374987-44-6
• 化学式: C₁₉H₂₉NO₄
• 分子量: 335.444
• InChiKey: JFIJFZDSQURFHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  24
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  48
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1-benzyl-5-bromo-5-(ethoxycarbonyl)-2,3,4,5-tetrahydropyridinium bromide 在 sodium ethanolate 作用下， 以 乙醇 为溶剂， 反应 2.0h， 以51%的产率得到ethyl 1-benzyl-2-(diethoxymethyl)pyrrolidine-2-carboxylate
  参考文献：
  名称：

  溴化四氢吡啶鎓：对官能化吡咯烷有用的合成子

  摘要：

  1-苄基-5-（乙氧羰基）-2,3,4,5-四氢吡啶鎓溴化物与一系列亲核试剂发生环收缩，得到2,2-二取代的吡咯烷。此外，从一些新的2,2-二取代的吡咯烷合成了螺吡咯烷。J.杂环化​​学。，（2011）。

  DOI：

  10.1002/jhet.823

文献信息

• CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF
  申请人：Beijing Lihe Technology Ltd.

  公开号：US20170283530A1

  公开（公告）日：2017-10-05

  Provided is a solid catalyst component for olefin polymerization, which comprises Mg, Ti, a halogen and an electron donor. The electron donor is selected from at least one of ring-substituted ether-acid ester compounds of the general formula (I). Also provided are a catalyst containing the solid catalyst component and the application of the catalyst in reactions of olefin polymerization, particularly in the reaction of propylene polymerization.

  提供了一种用于烯烃聚合的固体催化剂组分，包括镁、钛、卤素和电子给体。电子给体从通式（I）的环取代醚酸酯化合物中至少选择一个。还提供了含有该固体催化剂组分的催化剂以及在烯烃聚合反应中应用该催化剂的方法，特别是在丙烯聚合反应中的应用。
• Catalyst component for olefin polymerization and application thereof
  申请人：Beijing Lihe Technology Ltd.

  公开号：US10208146B2

  公开（公告）日：2019-02-19

  Provided is a solid catalyst component for olefin polymerization, which comprises Mg, Ti, a halogen and an electron donor. The electron donor is selected from at least one of ring-substituted ether-acid ester compounds of the general formula (I). Also provided are a catalyst containing the solid catalyst component and the application of the catalyst in reactions of olefin polymerization, particularly in the reaction of propylene polymerization.

  本发明提供了一种用于烯烃聚合的固体催化剂组分，它由 Mg、Ti、卤素和电子供体组成。电子供体选自通式（I）的环取代醚酸酯化合物中的至少一种。此外，还提供了一种含有固体催化剂组分的催化剂，以及该催化剂在烯烃聚合反应，特别是丙烯聚合反应中的应用。
• OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF
  申请人：Renqiu Lihe Technology Ltd.

  公开号：US20170355792A1

  公开（公告）日：2017-12-14

  Provided is an olefin polymerization catalyst carrier with a general structure formula of Mg(OR I ) n (OR II ) 2-n , wherein: 0≦n≦2, and R I and R II can be the same or different and are each independently selected from a C 1 -C 20 hydrocarbon group. In the X-ray diffraction pattern of the catalyst carrier, there are a set of diffraction peaks in the range of a 2θ diffraction angle of 5°-15°, and the set of diffraction peaks contain 1-4 main diffraction peaks. Also disclosed is an olefin polymerization solid catalyst component which is prepared from the carrier Mg(OR I ) n (OR II ) 2-n , a titanium compound, and at least one electron donor compound. In addition, also disclosed is an olefin polymerization catalyst containing the solid catalyst component, at least one organic aluminum compound, and optionally, an external electron donor compound.
• Tetrahydropyridinium bromide: Useful synthon to functionalized pyrrolidines
  作者：Luca Guideri、Rossella Noschese、Fabio Ponticelli

  DOI：10.1002/jhet.823

  日期：2012.3

  1‐benzyl‐5‐(ethoxycarbonyl)‐2,3,4,5‐tetrahydropyridinium bromide undergoes ring contraction with a series of nucleophiles, getting 2,2‐disubstitued pyrrolidines. Moreover, from some of the new 2,2‐disubstitued pyrrolidines were synthesized spiro‐pyrrolidines. J. Heterocyclic Chem.,(2011).

  1-苄基-5-（乙氧羰基）-2,3,4,5-四氢吡啶鎓溴化物与一系列亲核试剂发生环收缩，得到2,2-二取代的吡咯烷。此外，从一些新的2,2-二取代的吡咯烷合成了螺吡咯烷。J.杂环化​​学。，（2011）。