Cyclohexyl-(1-phenyl-vinyl)-carbodiimide | 215719-55-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Cyclohexyl-(1-phenyl-vinyl)-carbodiimide
• CAS: 215719-55-4
• 化学式: C₁₅H₁₈N₂
• 分子量: 226.321
• InChiKey: JOAFFITYQFVCJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  24.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(4-甲氧基苯基)-1H-吡咯-2,5-二酮 、 Cyclohexyl-(1-phenyl-vinyl)-carbodiimide 以 xylene 为溶剂， 反应 2.0h， 以36%的产率得到4-Cyclohexylamino-2-(4-methoxy-phenyl)-6-phenyl-pyrrolo[3,4-c]pyridine-1,3-dione
  参考文献：
  名称：

  热或路易斯酸促进的电环化和α，β-不饱和（共轭）碳二亚胺的杂Diels-Alder环加成：含氮杂环的简便合成

  摘要：

  由亚氨基膦酸酯与异氰酸酯的aza-Wittig反应制得的α，β-二芳基乙烯基-和α-苯乙烯基-碳二亚胺在加热或路易斯酸促进的条件下，通过适当的亲二烯体在加热或路易斯酸促进的条件下进行6π-电环化或Diels-Alder反应。作为四氰基乙烯，乙炔二甲酸二甲酯，马来酰亚胺，丙酸乙酯和异氰酸甲苯磺酯，得到异喹啉，吡啶，恶嗪，嘧啶和吡咯并吡啶。相反，即使在严格的反应条件下，β-苯乙烯基碳二亚胺对电环化或Diels-Alder反应也完全不反应。4-Coumarylcarbodiimide通过烯胺加热或在路易斯酸催化剂存在下与烯胺进行逆电子需求的Diels-Alder反应，得​​到苯并吡啶。

  DOI：

  10.1039/a805574b
• 作为产物：
  描述：

  苯乙烯 在 2,2'-联吡啶 、 chloro(1,5-cyclooctadiene)rhodium(I) dimer 、 sodium azide 、 一氯化碘 作用下， 以 1,4-二氧六环 、 二氯甲烷 、 乙腈 为溶剂， 反应 10.0h， 生成 Cyclohexyl-(1-phenyl-vinyl)-carbodiimide
  参考文献：
  名称：

  乙烯基叠氮化物与异腈和炔烃/苯并炔的Rh催化反应

  摘要：

  与通过叠氮基中间体或起始于烯烃部分的乙烯基叠氮化物的众所周知的转化相反，本文中我们报道了Rh（I）催化的叠氮化物部分上的乙烯基叠氮化物与异腈形成活性乙烯基碳二亚胺中间体并随后串联与不饱和化合物（例如炔烃和苯炔烃）环合，得到不同种类的氮杂杂环。从机理上讲，受控实验和DFT计算表明，Rh-nitrene是第一步偶联过程中的重要物质，Rh（I）催化剂也可以在炔烃的环化步骤中发挥重要作用。

  DOI：

  10.1021/acs.orglett.8b03115

文献信息

• VINYL RESIN AND RESIN COMPOSITION
  申请人：SANYO CHEMICAL INDUSTRIES, LTD.

  公开号：US20150119497A1

  公开（公告）日：2015-04-30

  The present invention aims to provide a vinyl resin which, with a polyurethane resin, is capable of providing a film excellent in mechanical strength, weather resistance, solvent resistance, and water resistance. The vinyl resin (V1) of the present invention is obtainable by polymerizing monomer components including a monomer (X) represented by the formula (1): wherein M 1 is a hydroxy group or a residue of an active hydrogen-containing organic compound having a valence of 1 to 20 from which c number of active hydrogen atoms are removed; c is 1 if M 1 is a hydroxy group, or c is an integer satisfying 1≦c≦(valence of M 1 ) if M 1 is a residue of an active hydrogen-containing organic compound having a valence of 1 to 20 from which c number of active hydrogen atoms are removed; R 1 is an ethylenic unsaturated bond-containing group, and when the formula (1) includes multiple R1's, they may be the same as or different from each other; M 2 is a hydroxy group or a residue of an active hydrogen-containing organic compound having a valence of 1 to 20 from which one active hydrogen atom is removed, and when the formula (1) includes multiple M 2 's, they may be the same as or different from each other, and M 2 and M 1 may be the same as or different from each other; L is a residue of an aromatic polycarboxylic acid having 3 or more carboxyl groups from which all the carboxyl groups are removed, the aromatic ring of L is constituted by carbon atoms, and each of the carbon atoms may optionally have a halogen atom and/or a substituent which is not a carboxyl group, but at least one of the carbon atoms has a hydrogen atom; a and b are each an integer of 0 or greater and they satisfy 2≦(a+b)≦(d−2), when the formula (1) includes multiple a's, they may be the same as or different from each other and at least one of c number of a's is not 0, and when the formula (1) includes multiple b's, they may be the same as or different from each other; and d is the number of hydrogen atoms bonded to the carbon atoms constituting the aromatic ring assuming that all the substituents including the carboxyl groups of the aromatic polycarboxylic acid are replaced by hydrogen atoms, in other words, the number of moieties capable of being replaced by a substituent on the aromatic ring.

  本发明旨在提供一种乙烯基树脂，该树脂与聚氨酯树脂一起使用，能够提供机械强度、耐候性、耐溶剂性和耐水性优异的膜。本发明的乙烯基树脂（V1）可通过聚合单体组分获得，该组分包括由式（1）表示的单体（X）：其中M1是具有1到20个活性氢原子的具有价为1到20的活性氢含有机化合物的羟基或残基，从中去除了c个活性氢原子，则当M1是羟基时，c为1，或当M1是具有价为1到20的活性氢含有机化合物的残基时，c是满足1≤c≤（M1的价）的整数；R1是含有乙烯基不饱和键的基团，当式（1）包括多个R1时，它们可以相同或不同；M2是具有1到20个活性氢原子的具有价为1到20的活性氢含有机化合物的羟基或残基，从中去除了一个活性氢原子，当式（1）包括多个M2时，它们可以相同或不同，且M2和M1可以相同或不同；L是具有3个或更多羧基的芳香族多羧酸的残基，L的芳香环由碳原子构成，每个碳原子可以选择性地具有卤素原子和/或不是羧基的取代基，但至少有一个碳原子具有氢原子；a和b分别是大于或等于0的整数，它们满足2≤（a+b）≤（d-2），当式（1）包括多个a时，它们可以相同或不同，并且c个a中至少有一个不为0，当式（1）包括多个b时，它们可以相同或不同；d是假设芳香环上包括羧基的所有取代基都被氢原子取代的碳原子上结合的氢原子数，换句话说，是能够被芳香环上取代基替换的基团数。
• Rh-Catalyzed Reaction of Vinyl Azides with Isonitriles and Alkynes/Benzynes
  作者：Zongyang Li、Tongyu Huo、Li Li、Shuo Feng、Qian Wang、Zhen Zhang、Sen Pang、Zhiyuan Zhang、Peng Wang、Zhenhua Zhang

  DOI：10.1021/acs.orglett.8b03115

  日期：2018.12.21

  In contrast to well-known transformations of vinyl azides via azirine intermediates or initiating at the alkene moiety, herein we report a Rh(I)-catalyzed coupling reaction of vinyl azides with isonitriles at the azide moiety to form active vinyl carbodiimide intermediates and following tandem cyclization with unsaturated compounds, such as alkynes and benzynes, to give different classes of azaheterocycles

  与通过叠氮基中间体或起始于烯烃部分的乙烯基叠氮化物的众所周知的转化相反，本文中我们报道了Rh（I）催化的叠氮化物部分上的乙烯基叠氮化物与异腈形成活性乙烯基碳二亚胺中间体并随后串联与不饱和化合物（例如炔烃和苯炔烃）环合，得到不同种类的氮杂杂环。从机理上讲，受控实验和DFT计算表明，Rh-nitrene是第一步偶联过程中的重要物质，Rh（I）催化剂也可以在炔烃的环化步骤中发挥重要作用。
• Thermal or Lewis acid-promoted electrocyclisation and hetero Diels–Alder cycloaddition of α,β-unsaturated (conjugated) carbodiimides: a facile synthesis of nitrogen-containing heterocycles
  作者：Takao Saito、Takahiro Ohkubo、Hideki Kuboki、Masayuki Maeda、Kensaku Tsuda、Takayuki Karakasa、Sadayoshi Satsumabayashi

  DOI：10.1039/a805574b

  日期：——

  β-styrylcarbodiimide was entirely unreactive toward either the electrocyclisation or the Diels–Alder reaction even under severe reaction conditions. 4-Coumarylcarbodiimide underwent an inverse electron-demand Diels–Alder reaction with an enamine either thermally or in the presence of a Lewis acid catalyst to afford chromenopyridines. Thus experimentally observed reactivity differences of the substituted

  由亚氨基膦酸酯与异氰酸酯的aza-Wittig反应制得的α，β-二芳基乙烯基-和α-苯乙烯基-碳二亚胺在加热或路易斯酸促进的条件下，通过适当的亲二烯体在加热或路易斯酸促进的条件下进行6π-电环化或Diels-Alder反应。作为四氰基乙烯，乙炔二甲酸二甲酯，马来酰亚胺，丙酸乙酯和异氰酸甲苯磺酯，得到异喹啉，吡啶，恶嗪，嘧啶和吡咯并吡啶。相反，即使在严格的反应条件下，β-苯乙烯基碳二亚胺对电环化或Diels-Alder反应也完全不反应。4-Coumarylcarbodiimide通过烯胺加热或在路易斯酸催化剂存在下与烯胺进行逆电子需求的Diels-Alder反应，得​​到苯并吡啶。