(E)-2,7-octadienoic acid | 51148-79-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-2,7-octadienoic acid
• 英文别名: 2,7-Octadiensaeure；2,7-octadienoic acid；2E,7-Octadienoic acid；(2E)-octa-2,7-dienoic acid
• CAS: 51148-79-9
• 化学式: C₈H₁₂O₂
• 分子量: 140.182
• InChiKey: NZEBVMIRSIBPJJ-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 (E)-2,7-octadienoic acid 生成 1-(methoxycarbonyl)-1,6-heptadiene
  参考文献：
  名称：

  Process for synthesizing zearalanone and related compounds

  摘要：

  本发明提供了一种新的合成方法，用于制备Zearalanone及其非芳香环中比Zearalanone碳原子数更多或更少的相关化合物，其中这些相关化合物和Zearalanone由以下公式表示：##SPC1## 其中X是一个整数，其值为2到6，包括2和6，Y是一个整数，其值为2到8，包括2和8。它还提供了制备在Zearalanone和相关化合物的合成中有用的新化合物的方法。新的中间体化合物包括2,7-辛二烯酸；甲基2,7-辛二烯酸酯；乙基6-(4-戊烯基)-β-二氢雷司酸钠盐；乙基6-(4-戊烯基)-β-二氢雷司酸酯；甲基6-(4-戊烯基)-β-二氢雷司酸钠盐；甲基6-(4-戊烯基)-β-二氢雷司酸酯；甲基3-溴-6-(4-戊烯基)-β-二氢雷司酸酯；甲基6-(4-戊烯基)-β-雷司酸酯；乙基6-(4-戊烯基)-β-雷司酸酯；乙基6-(4-戊烯基)-β-雷司酸酯二苯甲醚；以及4-戊烯-2-基6-(4-戊烯基)-β-雷司酸酯二苯甲醚。

  公开号：

  US03957825A1
• 作为产物：
  描述：

  1-(methoxycarbonyl)-1,6-heptadiene 在 sodium hydroxide 作用下， 以 四氢呋喃 、 1,4-二氧六环 为溶剂， 反应 3.0h， 生成 (E)-2,7-octadienoic acid
  参考文献：
  名称：

  手性烯丙基叠氮化物的空间偏向3,3-Sigmatropic重排：在生物碱的总合成中的应用

  摘要：

  We describe a tandem Mitsunobu/3,3-sigmatropic rearrangement of allylic azides on a chiral auxiliary system that favors one regioisomer thanks to its exceptional steric bias. The sequence may be completed by the oxidative cleavage of the auxiliary or by a ring-closing metathesis reaction that produces a carboor heterocycle directly and a recyclable form of the chiral auxiliary. Applications of the methodology to the total synthesis of (+)-coniine, (+)-lentiginosin, and (+)-pumiliotoxin C are reported.

  DOI：

  10.1021/jo800817p

文献信息

• [EN] PROCESS TO PREPARE EPSILON-CAPROLACTAM<br/>[FR] PROCÉDÉ POUR PRÉPARER DE L'EPSILON-CAPROLACTAME
  申请人：UNIV LEIDEN

  公开号：WO2014163506A1

  公开（公告）日：2014-10-09

  The invention is directed to a process to prepare ε-caprolactam and/or unsaturated ε-caprolactam from a pentenamide by contacting the pentenamide with a mixture of hydrogen and carbon monoxide in the presence of a solvent and a catalyst system comprising of a Group 8-10 metal and a phosphorus-donor ligand. The ligand may be a xantphos-type ligand.

  该发明涉及一种从戊烯酰胺通过将戊烯酰胺与氢和一氧化碳的混合物在溶剂和催化剂体系的存在下接触而制备ε-己内酰胺和/或不饱和ε-己内酰胺的方法。催化剂体系包括第8-10族金属和磷-供体配体。该配体可以是一种黄膜磷配体。
• [EN] PROCESS FOR THE PREPARATION OF FORMYLVALERIC ACID AND ADIPIC ACID<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ACIDE FORMYLAVÉRIQUE ET D'ACIDE ADIPIQUE
  申请人：DSM IP ASSETS BV

  公开号：WO2014111446A1

  公开（公告）日：2014-07-24

  The invention relates to a process for the production of 5-formylvaleric acid and adipic acid or esters thereof from an isomeric mixture of pentenoic acid or esters thereof said mixture comprising at least 4-pentenoic acid or esters thereof, and further comprising 3-pentenoic acid and/or 2-pentenoic acid or esters thereof, theprocess comprising: (a) subjecting the isomeric mixture of pentenoic acid to a hydroformylation reaction comprising a hydroformylation catalyst which is non-isomerizing towards the pentenoic acid or esters thereof to obtain a mixture comprising 5-formylvaleric acid or esters thereof and further comprising 3-pentenoic acid and/or 2-pentenoic acid, or esters thereof; (b) separating the 3-pentenoic acid and/or 2-pentenoic acid, or esters thereof from the 5-formylvaleric acid or esters thereof; (c) subjecting the separated pentenoic acids or esters thereof to a carbonylation reaction comprising an isomerizing carbonylation catalyst to obtain adipic acid or esters thereof; (d) optionally isolating the adipic acid or ester thereof; and (e) optionally isolating the separated 5-formylvaleric acid or esters thereof. The process allows for efficient production of two different intermediates for producing polyamide using a single process, with good selectivity, little waste, in an economically efficient fashion. The process is very suitable to use an isomeric pentenoic acid mixture obtained from valerolactone, and can be used to produce renewable polyamide intermediates using a single process.

  本发明涉及一种从戊烯酸异构体混合物或其酯中生产5-甲酰基戊二酸和己二酸或其酯的工艺，所述混合物包括至少4-戊烯酸或其酯，并进一步包括3-戊烯酸和/或2-戊烯酸或其酯，该工艺包括：(a)将戊烯酸异构体混合物经过羰基化催化剂催化的羰基化反应，该催化剂对戊烯酸或其酯不进行异构化，以得到包括5-甲酰基戊二酸或其酯和进一步包括3-戊烯酸和/或2-戊烯酸或其酯的混合物；(b)将3-戊烯酸和/或2-戊烯酸或其酯与5-甲酰基戊二酸或其酯分离；(c)将分离的戊烯酸或其酯经过异构化羰基化催化剂催化的羰基化反应，以得到己二酸或其酯；(d)可选择性地分离己二酸或其酯；以及(e)可选择性地分离分离的5-甲酰基戊二酸或其酯。该工艺允许使用单一工艺高效生产用于制造聚酰胺的两种不同的中间体，具有良好的选择性，少量废料，经济高效。该工艺非常适合使用从缩酮酸获得的异构戊烯酸混合物，并可用于使用单一工艺生产可再生聚酰胺中间体。
• Process for the preparation of epsilon-Caprolactam
  申请人：DSM N.V.

  公开号：EP1251122A1

  公开（公告）日：2002-10-23

  The invention relates to a process for the preparation of ε-caprolactam, wherein ε-caprolactam is prepared starting from butadiene, carbon monoxide, hydrogen and ammonia and the process comprises: 1. carbonylating butadiene in the presence of an alkanol and a catalyst comprising palladium, a multidentate phosphine ligand and an acidic co-catalyst to produce alkyl-4-, alkyl-3- and alkyl-2-pentenoate, 1'. optionally isomerising the alkyl-3- and/or alkyl-2-pentenoate into alkyl-4-pentenoate, 2. hydroformylating the alkyl-4-, alkyl-3- and alkyl-2-pentenoate in the presence of a catalyst comprising rhodium and an organic phosphorous containing ligand to produce alkyl-5-formylvalerate, 3. reductively aminating alkyl-5-formylvalerate in the presence of a hydrogenation catalyst comprising ruthenium on a carrier catalyst to produce ε-caprolactam and ε-caprolactam precursors, 4. optionally converting ε-caprolactam precursors at elevated temperature into ε-caprolactam.

  本发明涉及一种制备ε-己内酰胺的方法，其中从丁二烯、一氧化碳、氢气和氨开始制备ε-己内酰胺，该方法包括：1. 在存在烷基醇和钯、多齿膦配体和酸性协同催化剂的催化剂的存在下，将丁二烯羰基化以产生烷基-4-、烷基-3-和烷基-2-戊烯酸酯；1'。可选地，将烷基-3-和/或烷基-2-戊烯酸酯异构化为烷基-4-戊烯酸酯；2. 在存在铑和含有有机磷配体的催化剂的存在下，对烷基-4-、烷基-3-和烷基-2-戊烯酸酯进行氢羰基化，以产生烷基-5-甲酰缬氨酸；3. 在载体催化剂上存在钌的氢化催化剂的存在下，还原性地氨基化烷基-5-甲酰缬氨酸，以产生ε-己内酰胺和ε-己内酰胺前体；4. 在必要时将ε-己内酰胺前体在高温下转化为ε-己内酰胺。
• AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20150045409A1

  公开（公告）日：2015-02-12

  An amide compound represented by formula (I) has an excellent pest control effect. (In the formula, Y represents a 3-7 membered saturated heterocyclic ring which contains, as ring-forming components(s), one or more atoms or groups that are selected from the group consisting of an oxygen atom and —S(O) t —, the saturated heterocyclic ring may have one to three atoms or groups selected from group D and t represents 0 or the like; X represents a C 1 -C 10 chain hydrocarbon group which may have one or more atoms or groups that are selected from group A, or the like; W represents —CR 8 — or the like; r represents 1 or the like; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 may be the same or different and each represents a hydrogen atom or the like; and n represents 1 or the like.)

  化合物式(I)所代表的酰胺化合物具有优异的杀虫效果。（在该式中，Y代表一个3-7个成员的饱和杂环环，其中包含一个或多个被选择自由基或原子的组分，该组分被选择自由基或原子的组包括氧原子和—S(O)t—，饱和杂环环可能具有来自D组的一个到三个原子或自由基，t代表0或类似物；X代表一个C1-C10链烃基，该烃基可能具有一个或多个被选择自由基或原子的组分，该组分被选择自由基或原子的组包括A组或类似物；W代表—CR8—或类似物；r代表1或类似物；R1、R2、R3、R4、R5、R6、R7和R8可能相同也可能不同，每个代表氢原子或类似物；n代表1或类似物。）
• Supported bis(phosphorus) ligands and use thereof in hydrocyanation processes
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP1214975A2

  公开（公告）日：2002-06-19

  Supported bis(phosphorus) ligands are disclosed for use in a variety of catalytic processes, including the hydrocyanation of unsaturated organic compounds. The supported bis(phosphorus) ligand is one according to formula (2): wherein: Q is any organic fragment which binds a OPX2 moiety to the support (Sup); and X is an alkoxide, aryloxide, alkyl, or aryl.

  所公开的支撑双（磷）配体可用于各种催化过程，包括不饱和有机化合物的氢氰化。 支撑双（磷）配体为符合式（2）的配体： 其中 Q 是将 OPX2 分子与支撑体（Sup）结合的任何有机片段；以及 X 是烷氧基、芳氧基、烷基或芳基。