1,6-bis(4-vinylbenzyloxy)hexane | 122085-38-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,6-bis(4-vinylbenzyloxy)hexane
• 英文别名: 1,6-di(4-vinylbenzyloxy)hexane；1,6-Bis(4vinylbenzyloxy)hexane；1-ethenyl-4-[6-[(4-ethenylphenyl)methoxy]hexoxymethyl]benzene
• CAS: 122085-38-5
• 化学式: C₂₄H₃₀O₂
• 分子量: 350.501
• InChiKey: RWGKANAENSHCKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  26
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,6-己二醇 、 4-氯甲基苯乙烯 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以63 %的产率得到1,6-bis(4-vinylbenzyloxy)hexane
  参考文献：
  名称：

  WO2023/69599

  摘要：

  公开号：

文献信息

• A Polymer-Supported Chiral Dirhodium(II) Complex: Highly Durable and Recyclable Catalyst for Asymmetric Intramolecular CH Insertion Reactions
  作者：Koji Takeda、Tadashi Oohara、Masahiro Anada、Hisanori Nambu、Shunichi Hashimoto

  DOI：10.1002/anie.201003730

  日期：2010.9.17

  A highly effective immobilization of [Rh2(S‐PTTL)4] (PTTL=N‐phthaloyl‐tert‐leucinate) has been achieved by copolymerization of monomer 1 with styrene and a flexible cross‐linker. The immobilized catalyst promoted the title reaction at −78 °C with high enantioselectivity, and could be used for up to 100 cycles with a low level of leaching (0.28 ppm).

  通过单体1与苯乙烯和柔性交联剂的共聚，已实现了[Rh 2（S -PTTL）4 ]（PTTL = N-邻苯二甲酰叔亮氨酸）的高效固定。固定化的催化剂在-78°C下以高对映选择性促进了标题反应，可在低浸出（0.28 ppm）的条件下用于多达100个循环。
• Polymer-supported protic functionalized ionic liquids for nucleophilic substitution reactions: superior catalytic activity compared to other ionic resins
  作者：Sandip S. Shinde、Byoung Se Lee、Dae Yoon Chi

  DOI：10.1016/j.tetlet.2008.04.151

  日期：2008.6

  Three polymer-supported quaternary ammonium mesylates were synthesized for recyclable polymeric phase transfer catalysts (PTCs). Through comparison study using nucleophilic fluorination, tertiary alcohol containing polymer 3c proved to be the best catalyst with high catalytic activity and chemoselectivity. It also exhibited not only superior activity in other nucleophilic substitution reactions, such

  合成了三种聚合物负载的甲磺酸季铵盐，用于可回收的聚合物相转移催化剂（PTC）。通过使用亲核氟化的比较研究，含叔醇的聚合物3c被证明是具有高催化活性和化学选择性的最佳催化剂。它不仅在其他亲核取代反应中表现出优异的活性，例如氯化，溴化，碘化，乙酰氧基化和叠氮化，而且在不损失催化活性或产物收率的情况下具有良好的可回收性。
• POLYMER CONTAINING CARBOXYL GROUP, PREPARATION METHOD AND APPLICATION THEREOF, SUPPORTED CATALYST AND PREPARATION METHODS THEREOF AND PREPARATION METHODS OF PENEM ANTIBIOTIC INTERMEDIATE
  申请人：Asymchem Laboratories (Tianjin) Co., Ltd.

  公开号：US20170136450A1

  公开（公告）日：2017-05-18

  A polymer containing a carboxyl group, a preparation method and an application thereof, a supported catalyst and a preparation method thereof and preparation methods of penem antibiotic intermediate are disclosed. The polymer has high rigidity and hardness, thus the mechanical properties of the polymer is effectively improved. Meanwhile, in the polymer, the carboxyl group is used as a main functional group, and is used as a carrier to prepare, by means of a coordination reaction between the carboxyl group and a heavy metal, a supported metal catalyst which has better connection stability between the metal and the polymer. The above two factors can improve the stability of the supported metal catalyst, such that the catalyst can be recycled without losing the catalytic activity. Meanwhile, loss of a heavy metal active ingredient and production cost can be reduced.
• WO2023/69599
  申请人：——

  公开号：——

  公开（公告）日：——