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N-[6-(6-purinylamino)caproyloxy]succinimide | 331473-83-7

中文名称
——
中文别名
——
英文名称
N-[6-(6-purinylamino)caproyloxy]succinimide
英文别名
(2,5-dioxopyrrolidin-1-yl) 6-(7H-purin-6-ylamino)hexanoate
N-[6-(6-purinylamino)caproyloxy]succinimide化学式
CAS
331473-83-7
化学式
C15H18N6O4
mdl
——
分子量
346.346
InChiKey
FZKCLXUMTHXDES-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    0.4
  • 重原子数:
    25
  • 可旋转键数:
    9
  • 环数:
    3.0
  • sp3杂化的碳原子比例:
    0.47
  • 拓扑面积:
    130
  • 氢给体数:
    2
  • 氢受体数:
    8

上下游信息

  • 上游原料
    中文名称 英文名称 CAS号 化学式 分子量

反应信息

  • 作为反应物:
    描述:
    N-[6-(6-purinylamino)caproyloxy]succinimide 、 在 dipotassium hydrogenphosphate 作用下, 以 N,N-二甲基甲酰胺 为溶剂, 以60%的产率得到
    参考文献:
    名称:
    Multifunctional dinucleotide analogs for the generation of complex RNA conjugates
    摘要:
    Oligonucleotide conjugates are needed for in vitro selection schemes aiming at reactions between small, organic reactants. A general strategy is provided for the generation of the required RNA reactant conjugates based on multifunctional dinucleotide analogs. These modified dinucleotides allow for enzymatic ligation to native or enzymatically transcribed RNAs. They further contain a flexible polyethylene glycol spacer for correct spatial positioning and a photolabile cleavage site for selective release. The dinucleotides can be derivatized with the desired organic compounds by activated ester chemistry as was demonstrated by coupling to several nucleobases and nucleotides. (C) 2001 Elsevier Science Ltd. All rights reserved.
    DOI:
    10.1016/s0040-4020(00)01114-5
  • 作为产物:
    描述:
    参考文献:
    名称:
    Multifunctional dinucleotide analogs for the generation of complex RNA conjugates
    摘要:
    Oligonucleotide conjugates are needed for in vitro selection schemes aiming at reactions between small, organic reactants. A general strategy is provided for the generation of the required RNA reactant conjugates based on multifunctional dinucleotide analogs. These modified dinucleotides allow for enzymatic ligation to native or enzymatically transcribed RNAs. They further contain a flexible polyethylene glycol spacer for correct spatial positioning and a photolabile cleavage site for selective release. The dinucleotides can be derivatized with the desired organic compounds by activated ester chemistry as was demonstrated by coupling to several nucleobases and nucleotides. (C) 2001 Elsevier Science Ltd. All rights reserved.
    DOI:
    10.1016/s0040-4020(00)01114-5
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