3-Phenyl-dec-1-en-4-ol | 40596-18-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-Phenyl-dec-1-en-4-ol
• 英文别名: 3-phenyldec-1-en-4-ol
• CAS: 40596-18-7
• 化学式: C₁₆H₂₄O
• 分子量: 232.366
• InChiKey: MWOWANOVRCXDBS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.29
• 重原子数：
  17.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  4-oxo-3-phenyldec-1-ene 在 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 0.5h， 以82%的产率得到3-Phenyl-dec-1-en-4-ol
  参考文献：
  名称：

  Synthesis of enantiomerically enriched anti-homoallyl alcohols mediated by Crude Chicken Liver Esterase (CCLE)

  摘要：

  Enantiomerically enriched anti-homoallyl alcohols were synthesized in 67->99% enantiomeric purities via enantioselective hydrolysis of the corresponding racemic acetates mediated by Crude Chicken Liver Esterase (CCLE).

  DOI：

  10.1016/0957-4166(95)00075-z

文献信息

• Reversible stereocontrol in the Lewis acid promoted reaction of alkoxyaldehydes toward various allyltins
  作者：Yutaka Nishigaichi、Akio Takuwa

  DOI：10.1016/s0040-4039(02)02867-8

  日期：2003.2

  In the reactions of variously substituted allyltin reagents toward achiral alkoxyaldehydes, one of the diastereomeric homoallyl alcohols was stereoselectively obtained by the help of BF3, while TiCl4 preferentially gave the other diastereomer, though (E)- and (Z)-3-monoalkylallyltin reagents were exceptional. This reversible diastereoselectivity can be explained by the coordination geometry (anti or

  在各种取代的烯丙基锡试剂对非手性烷氧基醛的反应中，借助（BF）3立体选择性地获得了一种非对映异构的烯丙基醇，而（E）-和（Z）-3-单烷基烯丙基的TiCl 4优先提供了另一种非对映异构体。试剂是例外。这种可逆的非对映选择性可以通过路易斯酸对烷氧基醛的配位几何结构（反或顺）来解释。
• Reaction of Allylic-type Diindium Compounds with Electrophiles
  作者：Tsunehisa Hirashita、Shun Arai、Kazuma Mitsui、Hajime Makino、Shuki Araki

  DOI：10.1246/cl.2006.314

  日期：2006.3

  Allylic-type diindium reagents were prepared from 3-bromo-1-iodopropene (1a), 3-bromo-1-iodo-1-phenylpropene (1b), or 2,4-diiodobut-2-en-1-ol (1c) with metallic indium, and their successive coupling with electrophiles was examined. The coupling behavior of the diindium reagents was found to depend on the electrophiles and the substituent on the diindium compounds.

  以 3-溴-1-碘丙烯（1a）、3-溴-1-碘-1-苯基丙烯（1b）或 2,4-二碘丁-2-烯-1-醇（1c）为原料，用金属铟制备了烯丙基二铟试剂，并考察了它们与亲电体的连续偶联。研究发现，二铟试剂的偶联行为取决于亲电体和二铟化合物上的取代基。
• Gerard,F.; Miginiac,P., Bulletin de la Societe Chimique de France, 1974, p. 1924 - 1930
  作者：Gerard,F.、Miginiac,P.

  DOI：——

  日期：——
• Synthesis of enantiomerically enriched anti-homoallyl alcohols mediated by Crude Chicken Liver Esterase (CCLE)
  作者：Deevi Basavaiah、Polisetti Dharma Rao

  DOI：10.1016/0957-4166(95)00075-z

  日期：1995.3

  Enantiomerically enriched anti-homoallyl alcohols were synthesized in 67->99% enantiomeric purities via enantioselective hydrolysis of the corresponding racemic acetates mediated by Crude Chicken Liver Esterase (CCLE).