N-propionylnorleucine | 67206-11-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-propionylnorleucine
• 英文别名: 2-(Propanoylamino)hexanoic acid
• CAS: 67206-11-5
• 化学式: C₉H₁₇NO₃
• mdl: MFCD12173575
• 分子量: 187.239
• InChiKey: ZRHYJMJQIXVVRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.777
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Composition containing a penem or carbapenem antibiotic
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0226304B1

  公开（公告）日：1991-08-28
• NON-ENZYMATIC LIPOSOME-LINKED CLOSELY SPACED ARRAY ELECTRODES ASSAY (NEL-ELA) FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS
  申请人：Fraunhofer-Gesellschaft zurFörderung der angewandten Forschung e.V.

  公开号：EP1409728A2

  公开（公告）日：2004-04-21
• ACTIVATED ENZYME-LINKED DETECTION SYSTEMS FOR DETECTING AND QUANTIFYING NUCLEID ACIDS, ANTIGENS, ANTIBODIES AND OTHER ANALYTES
  申请人：FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DERANGEWANDTEN FORSCHUNG E.V.

  公开号：EP1448991A2

  公开（公告）日：2004-08-25
• US4757066A
  申请人：——

  公开号：US4757066A

  公开（公告）日：1988-07-12
• [EN] NON-ENZYMATIC LIPOSOME-LINKED CLOSELY SPACED ARRAY ELECTRODES ASSAY (NEL-ELA) FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS<br/>[FR] ANALYSE NON ENZYMATIQUE A LIAISON LIPOSOMIQUE AVEC ELECTRODES EN RESEAU ETROITEMENT ESPACEES (NEL-ELA) POUR DETECTER ET QUANTIFIER DES ACIDES NUCLEIQUES
  申请人：FRAUNHOFER GES FORSCHUNG

  公开号：WO2002081739A2

  公开（公告）日：2002-10-17

  Target nucleic acids or amplicons thereof bound to immobilized capture oligonucleotides by molecular biological reations, are detected and quantified with affinity liposomes containing encapsulated electrochemically detectable reporter molecules susceptible to redox recycling and surface-attached affinity components capable of specifically binding to captured target nucleic acids or amplicons thereof in a structure restricted manner. Specifically bound affinity liposomes are lysed by temperature- or detergent-mediated mechanisms and released reporter molecules are quantitated via redox recycling using voltammetry in conjunction with a closely spaced array of thin film nobel metal electrodes. The quantitiy of released reporter molecules is a proportional measure of the quantity of target nucleic acids in the sample. For amplified assay procedures polymeric carrier molecules capable of binding multiple affinity liposomes or preformed complexes of affinity liposomes are utilized.