(Z)-7-methyl-4,7-octadien-1-ol | 180624-70-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-7-methyl-4,7-octadien-1-ol
• 英文别名: (4Z)-7-methylocta-4,7-dien-1-ol
• CAS: 180624-70-8
• 化学式: C₉H₁₆O
• 分子量: 140.225
• InChiKey: ANVIATAYVATEJZ-HYXAFXHYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-7-methyl-4,7-octadien-1-ol 在 bis(2,4,6-trimethylpyridine)iodine(I) hexafluorophosphate 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以70%的产率得到2-(1-iodo-3-methyl-3-butenyl)tetrahydrofuran
  参考文献：
  名称：

  Preparation of Oxepanes, Oxepenes, and Oxocanes by Iodoetherification using Bis(sym-collidine)iodine(I) Hexafluorophosphate as Electrophile

  摘要：

  Oxepanes have been obtained in good yields (40-95%) by iodoetherification of unsaturated alcohols using bis(sym-collidine)iodine(I) hexafluorophosphate (1) as electrophile, either by 7-exo-mode or 7-endo-mode cyclizations. 4-Oxepenes could also be formed from 4,6-heptadien-1-ols; the presence of a substituent on the carbon 6 appeared necessary, while for steric reasons the presence of a substituent on the carbon 7 was unfavorable. Oxocanes could be obtained in moderate yields (18-27%).

  DOI：

  10.1021/jo960506t
• 作为产物：
  描述：

  7-methyloct-7-en-4-yn-1-ol 在 Pd-BaSO₄ 氢气 作用下， 以 吡啶 为溶剂， 以97%的产率得到(Z)-7-methyl-4,7-octadien-1-ol
  参考文献：
  名称：

  Preparation of Oxepanes, Oxepenes, and Oxocanes by Iodoetherification using Bis(sym-collidine)iodine(I) Hexafluorophosphate as Electrophile

  摘要：

  Oxepanes have been obtained in good yields (40-95%) by iodoetherification of unsaturated alcohols using bis(sym-collidine)iodine(I) hexafluorophosphate (1) as electrophile, either by 7-exo-mode or 7-endo-mode cyclizations. 4-Oxepenes could also be formed from 4,6-heptadien-1-ols; the presence of a substituent on the carbon 6 appeared necessary, while for steric reasons the presence of a substituent on the carbon 7 was unfavorable. Oxocanes could be obtained in moderate yields (18-27%).

  DOI：

  10.1021/jo960506t

文献信息

• Allylboration of Alkenes with Allyldihaloboranes
  作者：Daniel A. Singleton、Stephen C. Waller、Zongren Zhang、Doug E. Frantz、Shun-Wang Leung

  DOI：10.1021/ja961616k

  日期：1996.1.1
• Preparation of Oxepanes, Oxepenes, and Oxocanes by Iodoetherification using Bis(<i>sym</i>-collidine)iodine(I) Hexafluorophosphate as Electrophile
  作者：Yves Brunel、Gérard Rousseau

  DOI：10.1021/jo960506t

  日期：1996.1.1

  Oxepanes have been obtained in good yields (40-95%) by iodoetherification of unsaturated alcohols using bis(sym-collidine)iodine(I) hexafluorophosphate (1) as electrophile, either by 7-exo-mode or 7-endo-mode cyclizations. 4-Oxepenes could also be formed from 4,6-heptadien-1-ols; the presence of a substituent on the carbon 6 appeared necessary, while for steric reasons the presence of a substituent on the carbon 7 was unfavorable. Oxocanes could be obtained in moderate yields (18-27%).