(1S,3S,8R,11S,12R,16R)-6,14,14-trimethyl-11-phenylmethoxy-13,15,17-trioxatetracyclo[9.6.0.03,8.012,16]heptadec-6-en-2-one | 1346659-60-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (1S,3S,8R,11S,12R,16R)-6,14,14-trimethyl-11-phenylmethoxy-13,15,17-trioxatetracyclo[9.6.0.03,8.012,16]heptadec-6-en-2-one
• CAS: 1346659-60-6
• 化学式: C₂₄H₃₀O₅
• 分子量: 398.499
• InChiKey: LWRUOQNETQOHTB-QEDVPUAISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  54
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1,2:5,6-二-o-异亚丙基-alpha-d-ribo-3-己呋喃核糖 在 sodium periodate 、 四氧化锇 、 正丁基锂 、 sodium hydride 、 戴斯-马丁氧化剂 、 magnesium 、 溶剂黄146 作用下， 以 四氢呋喃 、 六甲基磷酰三胺 、 乙醚 、 二氯甲烷 、 水 为溶剂， 反应 42.0h， 生成 (1S,3S,8R,11S,12R,16R)-6,14,14-trimethyl-11-phenylmethoxy-13,15,17-trioxatetracyclo[9.6.0.03,8.012,16]heptadec-6-en-2-one
  参考文献：
  名称：

  Synthetic studies toward nortriterpenoids of schisandraceae family. Approach to the construction of functionalized C/D and A/B ring units of micrandilactone C and rubrifloradilactone B

  摘要：

  Construction of 6/7 fused bicycles featuring C/D rings of micrandilactone C and rubrifloradilactone B is reported through IMDA reaction of properly designed substrates. Also a route to the construction of a tricycle having A/B ring of nortriterpenoids of schisandra family is reported using RCM and a bromonium ion initiated cycloetherification reaction as the key steps. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.09.104

文献信息

• Synthetic studies toward nortriterpenoids of schisandraceae family. Approach to the construction of functionalized C/D and A/B ring units of micrandilactone C and rubrifloradilactone B
  作者：Md. Firoj Hossain、Kiran Matcha、Subrata Ghosh

  DOI：10.1016/j.tetlet.2011.09.104

  日期：2011.11

  Construction of 6/7 fused bicycles featuring C/D rings of micrandilactone C and rubrifloradilactone B is reported through IMDA reaction of properly designed substrates. Also a route to the construction of a tricycle having A/B ring of nortriterpenoids of schisandra family is reported using RCM and a bromonium ion initiated cycloetherification reaction as the key steps. (C) 2011 Elsevier Ltd. All rights reserved.