N-(2-chloroprop-2-enyl)-4-nitrobenzamide | 500886-91-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2-chloroprop-2-enyl)-4-nitrobenzamide
• CAS: 500886-91-9
• 化学式: C₁₀H₉ClN₂O₃
• 分子量: 240.646
• InChiKey: PPSZUWLUUFGOHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  74.9
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(2-chloroprop-2-enyl)-4-nitrobenzamide 在 氢氟酸 、 五氟化锑 作用下， 生成
  参考文献：
  名称：

  Selective Synthesis of gem-Chlorofluorinated Nitrogen-Containing Derivatives after Superelectrophilic Activation in Superacid HF/SbF₅

  摘要：

  The first direct selective synthesis of novel gem-chloro-fluorinated nitrogen-containing building blocks in super-acid is reported. The dramatic role of the chlorine atom on the reaction is shown by in situ NMR experiments and allows the involvement of a novel original superelectrophilic activation process in superacid HF/SbF5 to be postulated.

  DOI：

  10.1021/jo102225w

文献信息

• Selective Synthesis of <i>gem</i>-Chlorofluorinated Nitrogen-Containing Derivatives after Superelectrophilic Activation in Superacid HF/SbF₅
  作者：Fei Liu、Agnès Martin-Mingot、Marie-Paule Jouannetaud、Christian Bachmann、Gilles Frapper、Fabien Zunino、Sébastien Thibaudeau

  DOI：10.1021/jo102225w

  日期：2011.3.4

  The first direct selective synthesis of novel gem-chloro-fluorinated nitrogen-containing building blocks in super-acid is reported. The dramatic role of the chlorine atom on the reaction is shown by in situ NMR experiments and allows the involvement of a novel original superelectrophilic activation process in superacid HF/SbF5 to be postulated.