5,5-difluoro-3,7-bis(4-methoxyphenyl)-1,9-dimethyl-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,5,2]triazaborinin-4-ium | 1443250-02-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 5,5-difluoro-3,7-bis(4-methoxyphenyl)-1,9-dimethyl-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,5,2]triazaborinin-4-ium
• CAS: 1443250-02-9
• 化学式: C₂₄H₂₂BF₂N₃O₂
• 分子量: 433.265
• InChiKey: OZERORNSZWCAPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  1-(4-methoxyphenyl)-but-2-en-1-one 在 ammonium acetate 、 二乙胺 、 N,N-二异丙基乙胺 作用下， 以 甲醇 、 乙醇 、 二氯甲烷 为溶剂， 反应 21.0h， 生成 5,5-difluoro-3,7-bis(4-methoxyphenyl)-1,9-dimethyl-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,5,2]triazaborinin-4-ium
  参考文献：
  名称：

  Synthesis and Properties of BF₂-3,3′-Dimethyldiarylazadipyrromethene Near-Infrared Fluorophores

  摘要：

  The first synthesis of both organic and aqueous soluble BF2 chelated 3,3'-dimethyl-5,5'-diarylazadipyrromethenes has been achieved. The fluorophores are emissive in organic and aqueous solvents with high quantum yields in the key biological near-infrared (NIR) spectral region of 675-700 nm. Following efficient cellular uptake from aqueous media the fluorophore can be readily visualized with confocal microscopy.

  DOI：

  10.1021/ol401434c

文献信息

• Synthesis and Properties of BF₂-3,3′-Dimethyldiarylazadipyrromethene Near-Infrared Fluorophores
  作者：Dan Wu、Donal F. O’Shea

  DOI：10.1021/ol401434c

  日期：2013.7.5

  The first synthesis of both organic and aqueous soluble BF2 chelated 3,3'-dimethyl-5,5'-diarylazadipyrromethenes has been achieved. The fluorophores are emissive in organic and aqueous solvents with high quantum yields in the key biological near-infrared (NIR) spectral region of 675-700 nm. Following efficient cellular uptake from aqueous media the fluorophore can be readily visualized with confocal microscopy.