2,3-dihydro-1H-1,5-benzodiazepin-4-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 英文名称: 2,3-dihydro-1H-1,5-benzodiazepin-4-amine
• 化学式: C₉H₁₁N₃
• 分子量: 161.2
• InChiKey: FONTWQOXMATVLS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  50.4
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• FORMULATIONS OF BENZAZEPINE CONJUGATES AND USES THEREOF
  申请人：Silverback Therapeutics, Inc.

  公开号：EP4013456A1

  公开（公告）日：2022-06-22
• Formulations of Benzazepine Conjugates and Uses Thereof
  申请人：Silverback Therapeutics, Inc.

  公开号：US20210077632A1

  公开（公告）日：2021-03-18

  Aqueous formulations comprising conjugates that comprise a compound comprising benzazepine or a benzazepine-like structure conjugated to a polypeptide are provided, as well as methods of treatment using the aqueous formulations. Lyophilized compositions comprising the conjugates that comprise a compound comprising benzazepine or a benzazepine-like structure conjugated to a polypeptide are also provided.
• [EN] FORMULATIONS OF BENZAZEPINE CONJUGATES AND USES THEREOF<br/>[FR] FORMULATIONS DE CONJUGUÉS DE BENZAZÉPINE ET LEURS UTILISATIONS
  申请人：SILVERBACK THERAPEUTICS INC

  公开号：WO2021030665A1

  公开（公告）日：2021-02-18

  Aqueous formulations comprising conjugates that comprise a compound comprising benzazepine or a benzazepine-like structure conjugated to a polypeptide are provided, as well as methods of treatment using the aqueous formulations. Lyophilized compositions comprising the conjugates that comprise a compound comprising benzazepine or a benzazepine-like structure conjugated to a polypeptide are also provided.