ethyl oximinoacetoacetate | 103851-18-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl oximinoacetoacetate
• 英文别名: ethyl (3E)-3-hydroxyiminobutanoate
• CAS: 103851-18-9
• 化学式: C₆H₁₁NO₃
• 分子量: 145.158
• InChiKey: RCKJUUVOLJLKQX-FNORWQNLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  58.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  ethyl oximinoacetoacetate 、 2-(benzylthio)benzylamine 以57%的产率得到2-<2-(benzylthio)phenyl>-4-carbethoxy-5-methylimidazole
  参考文献：
  名称：

  Biomimetic models for cysteine proteases. 1. Intramolecular imidazole catalysis of thiol ester solvolysis: a model for the deacylation step

  摘要：

  DOI：

  10.1021/ja00307a043

文献信息

• Method for deblocking a blocked isocyanate and method of making a polyurethane
  申请人：THE UNIVERSITY OF MASSACHUSETTS

  公开号：US11254784B2

  公开（公告）日：2022-02-22

  A method for deblocking a blocked isocyanate is described herein. The method includes contacting a blocked isocyanate and a halide ion source under conditions effective to provide a deblocked isocyanate. A method of making a polyurethane is also disclosed. The method of making a polyurethane includes combining a blocked isocyanate, a polyol, and a halide ion source in the presence of solvent and under conditions effective to provide the polyurethane.

  本文描述了一种解嵌异氰酸酯的方法。该方法包括在提供脱嵌异氰酸酯的有效条件下，将嵌段异氰酸酯与卤化离子源接触。还公开了一种制造聚氨酯的方法。制造聚氨酯的方法包括在有溶剂存在的情况下，在有效提供聚氨酯的条件下，将封端异氰酸酯、多元醇和卤化离子源结合在一起。
• MARKOVICH I. S.; FILYAGINA N. A.; RYABOKOBYLKO YU. S.; DZIOMKO V. M., ZH. BCEC. XIM. O-BA IM. D. I. MENDELEEVA, 1979, 24, HO 6, 644-646
  作者：MARKOVICH I. S.、 FILYAGINA N. A.、 RYABOKOBYLKO YU. S.、 DZIOMKO V. M.

  DOI：——

  日期：——
• KUZMIN, N. G.;SEMEJKIN, A. S.;KOJFMAN, O. I., TEZ. DOKL. 5 BCEC. KONF. PO KOORDINATS. I FIZ. XIMII PORFIRINOV, IVANOVO,+
  作者：KUZMIN, N. G.、SEMEJKIN, A. S.、KOJFMAN, O. I.

  DOI：——

  日期：——
• Substituted diphenylether compounds useful as herbicides
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0122037B1

  公开（公告）日：1987-08-19
• METHOD FOR DEBLOCKING A BLOCKED ISOCYANATE AND METHOD OF MAKING A POLYURETHANE
  申请人：THE UNIVERSITY OF MASSACHUSETTS

  公开号：US20200239623A1

  公开（公告）日：2020-07-30

  A method for deblocking a blocked isocyanate is described herein. The method includes contacting a blocked isocyanate and a halide ion source under conditions effective to provide a deblocked isocyanate. A method of making a polyurethane is also disclosed. The method of making a polyurethane includes combining a blocked isocyanate, a polyol, and a halide ion source in the presence of solvent and under conditions effective to provide the polyurethane.