N-(2,4-二硝基苯基)蛋氨酸 | 3950-28-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N-(2,4-二硝基苯基)蛋氨酸
• 英文名称: N-(2,4-Dinitro-phenyl)-methionin
• 英文别名: DL-Methionine, N-(2,4-dinitrophenyl)-；(2S)-2-(2,4-dinitroanilino)-4-methylsulfanylbutanoic acid
• CAS: 3950-28-5
• 化学式: C₁₁H₁₃N₃O₆S
• 分子量: 315.307
• InChiKey: DOHZIJDJOSBJFP-VIFPVBQESA-N

物化性质

• 沸点：
  587.4±50.0 °C(Predicted)
• 密度：
  1.518±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  166
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  L-蛋氨酸 、 2,4-二硝基苯磺酸二水合物 在 sodium hydroxide 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 3.0h， 以62%的产率得到N-(2,4-二硝基苯基)蛋氨酸
  参考文献：
  名称：

  磺酸的异丙基亲核取代合成邻硝基硝基芳基胺

  摘要：

  描述了一种温和，有效和环保的方法，该方法用于通过邻氨基芳基的ipso亲核芳基取代反应，由邻硝基芳基磺酸合成邻硝基芳基胺。无需任何金属，活化剂或有毒氧化剂的帮助，即可在室温下以高收率获得产品。该方法可用于无消旋地合成N-芳基氨基酸酯。

  DOI：

  10.1021/acs.orglett.8b03730

文献信息

• Compositions for use in golf balls
  申请人：Bulpett A. David

  公开号：US20050245652A1

  公开（公告）日：2005-11-03

  A golf ball comprises a core, an outer cover layer, and, optionally, an intermediate layer disposed between the core and the outer cover layer. The outer cover layer may comprise a polyurethane or polyurea composition. At least one portion of the golf ball comprises a composition that enhances physical properties and/or performance characteristics (e.g., coefficient of restitution) of the golf ball. Preferably, the coefficient of restitution of the core is 0.8 or greater.

  高尔夫球由内核、外覆盖层和可选的中间层组成，外覆盖层可以包括聚氨酯或聚脲组成。高尔夫球的至少一部分包含一种增强物理特性和/或性能特征（例如反弹系数）的组合物。最好，内核的反弹系数为0.8或更高。
• COMPOSITIONS FOR USE IN GOLF BALLS
  申请人：Sullivan Michael J.

  公开号：US20080227567A1

  公开（公告）日：2008-09-18

  A golf ball comprises a core, an outer cover layer, and, optionally, an intermediate layer disposed between the core and the outer cover layer. The outer cover layer may comprise a polyurethane or polyurea composition. At least one portion of the golf ball comprises a composition that enhances physical properties and/or performance characteristics (e.g., coefficient of restitution) of the golf ball. Preferably, the coefficient of restitution of the core is 0.8 or greater.

  一个高尔夫球包括一个核心、一个外覆盖层，以及可选的介质层，介质层位于核心和外覆盖层之间。外覆盖层可能包括聚氨酯或聚脲组成。高尔夫球的至少一部分包含一种增强高尔夫球物理性能和/或性能特征（例如反弹系数）的组成。最好，核心的反弹系数为0.8或更高。
• Compositions for Use in Golf Balls
  申请人：Bulpett David A.

  公开号：US20080176678A1

  公开（公告）日：2008-07-24

  A golf ball comprising a core and at least one layer disposed about the core, wherein at least one of the core or the layer is formed from a composition comprising a base polymer, a crosslink initiator, and an additive comprising an aromatic iodonium compound or an aromatic iodonium salt.

  一颗高尔夫球包括一个核心和至少一层沿核心排列的材料，其中核心或层中的至少一个是由包含基础聚合物、交联引发剂和添加剂的组合物形成的，该添加剂包括芳香碘化物或芳香碘化盐。
• Circular dichroism, ultraviolet, and proton nuclear magnetic resonance spectroscopic studies of the chiral recognition mechanism of .beta.-cyclodextrin
  作者：Song. Li、William C. Purdy

  DOI：10.1021/ac00037a019

  日期：1992.7.1

  The chiral recognition mechanism of beta-cyclodextrin was studied by UV-visible, circular dichroism, and proton nuclear magnetic resonance spectroscopic methods. The D and L enantiomers of DNP-valine, DNP-leucine, and DNP-methionine were used as model solutes. The results indicate that the dinitrophenyl group, which forms stable inclusion complexes with the beta-cyclodextrin cavity and places the other functional groups around the chiral center in association with the hydroxyl groups at the edge of the cavity, plays a very important role in the chiral recognition. The alkyl groups of amino acids, which form a secondary inclusion complex with another beta-cyclodextrin cavity (in the case of DNP-L-amino acids) or are sterically repulsed by the hydroxyl groups at the edge of the cavity (in the case of DNP-D-amino acids), are also major contributors to the chiral recognition process. The dissociation constants of the inclusion complexes of beta-cyclodextrin with these model compounds were also obtained from the changes of UV absorbance, elipticity, and chemical shifts, respectively. It was found that the DNP-L-amino acids always have smaller dissociation constants than the D-enantiomers.
• BARRA, M.;ROSSI, RITA H. DE, J. ORG. CHEM., 54,(1989) N1, C. 5020-5025
  作者：BARRA, M.、ROSSI, RITA H. DE

  DOI：——

  日期：——