N-<2-Hydroxy-3-methoxy-propyl>-morpholin | 3154-77-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: N-<2-Hydroxy-3-methoxy-propyl>-morpholin
• 英文别名: 1-methoxy-3-morpholin-4-yl-propan-2-ol；1-methoxy-3-morpholino-propan-2-ol；1-Methoxy-3-(morpholin-4-yl)propan-2-ol；1-methoxy-3-morpholin-4-ylpropan-2-ol
• CAS: 3154-77-6
• 化学式: C₈H₁₇NO₃
• mdl: MFCD02667741
• 分子量: 175.228
• InChiKey: DLSNTVMQVUYYRE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  41.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  (甲氧基甲基)环氧乙烷 、 吗啉 以48%的产率得到
  参考文献：
  名称：

  KIMSANOV, B. X.;ISHANOVA, X. X.;XAFIZOV, X. X.;BEGOVATOV, YU. M., IZV. AN TADZHSSR. OTD-NIE FIZ.-MAT., XIM. I GEOL. N., 1984, N 2, 72-74

  摘要：

  DOI：

文献信息

• Thiazolyl-Benzimidazoles
  申请人：Cai Jianping

  公开号：US20100160308A1

  公开（公告）日：2010-06-24

  The invention is directed to compounds of formula (1) and pharmaceutically acceptable salts thereof, methods for the preparation thereof, and methods of use thereof.

  这项发明涉及到式（1）的化合物及其药用可接受盐，其制备方法和使用方法。
• Fused pyrrolocarbazoles and methods for the preparation thereof
  申请人：Cephalon, Inc.

  公开号：EP2088150A1

  公开（公告）日：2009-08-12

  The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles.

  本发明一般涉及精选的融合吡咯并咔唑，包括其药物组合物以及用其治疗疾病的方法。本发明还涉及制造这些融合吡咯并咔唑的中间体和工艺。
• RUBBER COMPOSITION AND PNEUMATIC TIRE
  申请人：The Yokohama Rubber Co., Ltd.

  公开号：EP3564300A1

  公开（公告）日：2019-11-06

  Provided are a rubber composition and a pneumatic tire exhibiting superior workability. The rubber composition of the present invention includes: a diene rubber; silica; and a heterocyclic compound (the heterocyclic compound does not have a silicon atom) which includes a hydrocarbon group having from 3 to 30 carbons and at least one type of heterocycle selected from the group consisting of a piperazine ring, a morpholine ring and a thiomorpholine ring, and a content of the silica being from 50 to 200 parts by mass per 100 parts by mass of the diene rubber and a content of the heterocyclic compound being from 0.5 to 20% by mass with respect to the content of the silica.

  本发明提供了一种橡胶组合物和一种充气轮胎，具有优异的工作性能。本发明的橡胶组合物包括：二烯橡胶；白炭黑；杂环化合物（杂环化合物没有硅原子），杂环化合物包括具有 3 至 30 个碳原子的烃基和至少一种杂环，杂环选自由哌嗪环、吗啉环和硫吗啉环组成的组，白炭黑的含量为每 100 份二烯橡胶中白炭黑的质量分数为 50 至 200 份，杂环化合物的含量为白炭黑含量的 0.以质量计，杂环化合物的含量为白炭黑含量的 0.5%至 20%。
• Rubber composition and pneumatic tire
  申请人：The Yokohama Rubber Co., LTD.

  公开号：US11041062B2

  公开（公告）日：2021-06-22

  A rubber composition of the present technology includes: a diene rubber; silica; and a heterocyclic compound (the heterocyclic compound does not have a silicon atom) which includes a hydrocarbon group having from 3 to 30 carbons and at least one type of heterocycle selected from the group consisting of a piperazine ring, a morpholine ring and a thiomorpholine ring, and a content of the silica being from 50 to 200 parts by mass per 100 parts by mass of the diene rubber and a content of the heterocyclic compound being from 0.5 to 20% by mass with respect to the content of the silica.

  本技术的一种橡胶组合物包括：二烯橡胶；白炭黑；杂环化合物（杂环化合物不含硅原子），杂环化合物包括具有 3 至 30 个碳原子的烃基，以及至少一种选自哌嗪环、吗啉环和硫吗啉环的杂环，白炭黑的含量为每 100 份二烯橡胶中白炭黑的质量分数为 50 至 200 份，杂环化合物的含量为白炭黑含量的 0.以质量计，杂环化合物的含量为白炭黑含量的 0.5%至 20%。
• Rubber composition for tire, and pneumatic tire
  申请人：THE YOKOHAMA RUBBER CO., LTD.

  公开号：US11180634B2

  公开（公告）日：2021-11-23

  The present invention provides a rubber composition for a tire, the rubber composition containing: a diene rubber; silica; and a heterocyclic compound (where, the heterocyclic compound does not have a silicon atom) having a hydrocarbon group having from 3 to 30 carbons and at least one type of heterocycle selected from the group consisting of a piperazine ring, a morpholine ring, and a thiomorpholine ring; an average glass transition temperature of the diene rubber being −50° C. or higher; a content of the silica being from 80 to 200 parts by mass per 100 parts by mass of the diene rubber; and a content of the heterocyclic compound being from 0.5 to 20% by mass with respect to the content of the silica. Such rubber composition has excellent processability, exhibits excellent wet grip performance and has low rolling resistance when the rubber composition is formed into a tire.

  本发明提供了一种用于轮胎的橡胶组合物，该橡胶组合物包含：二烯橡胶；白炭黑；杂环化合物（其中，杂环化合物不含硅原子），该杂环化合物具有 3 至 30 个碳原子的烃基以及至少一种选自哌嗪环、吗啉环和硫吗啉环的杂环；二烯橡胶的平均玻璃化转变温度为 -50°C 或更高；白炭黑的含量为每 100 份二烯橡胶的质量的 80 至 200 份；杂环化合物的含量为相对于二烯橡胶质量的 0.5 至 20%。或更高；每 100 份二烯烃橡胶中白炭黑的含量为 80 至 200 份（以质量计）；杂环化合物的含量为白炭黑含量的 0.5 至 20%（以质量计）。这种橡胶组合物具有优异的加工性能，在将橡胶组合物制成轮胎时，具有优异的湿抓地性能和较低的滚动阻力。