trimethyl(pyren-1-ylmethoxy)silane | 1256281-76-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: trimethyl(pyren-1-ylmethoxy)silane
• CAS: 1256281-76-1
• 化学式: C₂₀H₂₀OSi
• 分子量: 304.464
• InChiKey: QPKOYTNWVBAKDX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.94
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  三甲基氯硅烷 、 1-芘甲醇 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 以68%的产率得到trimethyl(pyren-1-ylmethoxy)silane
  参考文献：
  名称：

  Ratiometric fluorescence chemodosimeters for fluoride anion based on pyrene excimer/monomer transformation

  摘要：

  我们设计了两种含有-O-Si-Si-O-或-O-Si-O-连接的芘二聚体，它们在氟化阴离子诱导的 Si-O 键裂解时会显示出按比率的准分子/单体发射。将探针掺入水溶性聚合物纳米粒子中可提高其在细胞内的吸收率，并在活细胞中显示出 F- 的比率荧光感应。

  DOI：

  10.1039/c2cc35967g

文献信息

• Room temperature silylation of alcohols catalyzed by metal organic frameworks
  作者：Amarajothi Dhakshinamoorthy、Andrea Santiago-Portillo、Patricia Concepción、José R. Herance、Sergio Navalón、Mercedes Alvaro、Hermenegildo Garcia

  DOI：10.1039/c7cy00834a

  日期：——

  The commercial Al(OH)(BDC) (BDC: 1,4-benzenedicarboxylic acid) metal organic framework (Basolite A100) is a suitable heterogeneous catalyst for the silylation of benzylic and aliphatic alcohols by hexamethyldisilazane in toluene at room temperature. Al(OH)(BDC) is stable under the reaction conditions as evidenced by powder XRD and can be reused with minimal activity decrease.

  商业化的Al（OH）（BDC）（BDC：1,4-苯二甲酸）金属有机骨架（Basolite A100）是一种适合的非均相催化剂，用于在室温下甲苯中六甲基二硅氮烷对苄基和脂族醇进行甲硅烷基化。粉末XRD证明Al（OH）（BDC）在反应条件下是稳定的，可以在活性降低最小的情况下重复使用。
• Sulfonated Ordered Nanoporous Carbon (CMK-5-SO3H) as an Efficient and Highly Recyclable Catalyst for the Silylation of Alcohols and Phenols with Hexamethyldisilazane (HMDS)
  作者：Daryoush Zareyee、Mohammad S. Ghandali、Mohammad A. Khalilzadeh

  DOI：10.1007/s10562-011-0621-3

  日期：2011.10

  An environmentally friendly catalytic system for trimethylsilylation of alcohols and phenols with hexamethyldisilazane can be successfully carried out for the first time over sulfonated mesoporous carbon catalyst (CMK-5-SO3H) in dichloromethane at ambient temperature and excellent conversions were obtained. Furthermore, the catalyst displays high activity and thermal stability (to 200 A degrees C) and it can be reused repeatedly for at least 25 cycles without any evidence of loss of activity, confirming the stability of covalent bonding of acidic centers.
• Ratiometric fluorescence chemodosimeters for fluoride anion based on pyrene excimer/monomer transformation
  作者：Lizhi Gai、Huachao Chen、Bin Zou、Hua Lu、Gaoqiao Lai、Zhifang Li、Zhen Shen

  DOI：10.1039/c2cc35967g

  日期：——

  Two pyrene dimers containing an –O–Si–Si–O− or −O–Si–O− linkage have been designed which exhibit ratiometric excimer/monomer emission upon fluoride anion induced Si–O bond cleavage. Incorporation of the probe into water soluble polymeric nanoparticles enhances its intracellular uptake and displays ratiometric fluorescent sensing for F− in living cells.

  我们设计了两种含有-O-Si-Si-O-或-O-Si-O-连接的芘二聚体，它们在氟化阴离子诱导的 Si-O 键裂解时会显示出按比率的准分子/单体发射。将探针掺入水溶性聚合物纳米粒子中可提高其在细胞内的吸收率，并在活细胞中显示出 F- 的比率荧光感应。