3-aminopropyl hexadecanoate | 1380680-71-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-aminopropyl hexadecanoate
• CAS: 1380680-71-6
• 化学式: C₁₉H₃₉NO₂
• 分子量: 313.524
• InChiKey: LYSXVMBEZOZVNS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  22
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-((tert-butoxycarbonyl)amino)propyl hexadecanoate 在 三氟乙酸 、 碳酸氢钠 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 0.5h， 以42%的产率得到3-aminopropyl hexadecanoate
  参考文献：
  名称：

  Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase

  摘要：

  N-Acylethanolamines (NAEs) including N-arachidonoylethanolamine (anandamide) and N-palmitoylethanolamine are endogenous lipid mediators. These molecules are degraded to the corresponding fatty acids and ethanolamine by fatty acid amide hydrolase (FAAH) or NAE-hydrolyzing acid amidase (NAAA). Lipophilic amines, especially pentadecylamine (2c) and tridecyl 2-aminoacetate (11b), were found to exhibit potent NAAA inhibitory activities (IC50 = 5.7 and 11.8 mu M), with much weaker effects on FAAH. These simple structures would provide a scaffold for further improvement in NAAA inhibitory activity. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2012.03.065

文献信息

• FLUORINE-CONTAINING POLYMER AND SURFACE TREATMENT AGENT
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP3865524A1

  公开（公告）日：2021-08-18

  Provided is a surface treatment agent comprising (A) a fluorine-containing polymer including a repeat unit derived from a fluorine-containing monomer (A1) and a repeat unit derived from a hydrocarbon group-bearing fluorine-free monomer (A2), and (B) a liquid medium. The fluorine-free monomer (A2) is preferably at least one monomer selected from the group consisting of (A2-1) R22-C(=O)-NH-R23-O-R21, (A2-2) CH2=C(-R32)-C(=O)-Y31-Z31(-Y32-R31)n, and (A2-3)X41N(H)r-R41. The surface treatment agent imparts an excellent water/oil repellency to base materials, e.g., fibers.

  本发明提供了一种表面处理剂，该表面处理剂包括 (A) 含氟聚合物，其中包括由含氟单体 (A1) 衍生的重复单元和由含烃基的无氟单体 (A2) 衍生的重复单元；以及 (B) 液体介质。无氟单体（A2）最好是至少一种选自以下组别的单体：(A2-1) R22-C(=O)-NH-R23-O-R21, (A2-2) CH2=C(-R32)-C(=O)-Y31-Z31(-Y32-R31)n, 和 (A2-3)X41N(H)r-R41。表面处理剂可使基材（如纤维）具有极佳的拒水/拒油性。
• Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives
  申请人：KYOWA HAKKO KOGYO CO., LTD

  公开号：EP0006227B1

  公开（公告）日：1984-12-27
• Novel benzamide derivatives
  申请人：KYOWA HAKKO KOGYO CO., LTD

  公开号：EP0062827B1

  公开（公告）日：1986-07-23
• EP3757187A1
  申请人：——

  公开号：EP3757187A1

  公开（公告）日：2020-12-30
• SURFACE TREATMENT AGENT
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：US20200377774A1

  公开（公告）日：2020-12-03

  A surface treatment agent containing: (A) a water repellent oil repellent polymer having a repeating unit derived from at least one water repellent oil repellent monomer selected from (A1) fluorine-containing monomers and (A2) non-fluorine monomers having a hydrocarbon group with 7-40 carbon atoms; (B) a silicone polymer represented by formula R 53 3 Si—O—[—Si(R 51 ) 2 —O—] a —[—Si(R 51 )(R 52 )—O—] b —SiR 53 3 (wherein each R 51 group independently represents hydrogen, alkyl having 1-20 carbon atoms, aryl having 6-20 carbon atoms or alkoxy having 1-4 carbon atoms; each R 52 independently represents a saturated hydrocarbon group having 23-40 carbon atoms; each R 53 independently represents a hydrogen atom, an alkyl group having 1-20 carbon atoms, an aryl group having 6-20 carbon atoms, an alkoxy group having 1-4 carbon atoms or a saturated hydrocarbon group having 23-40 carbon atoms; a represents an integer of 0 or more; b represents an integer of 1 or more; and (a+b) is 10-200); and (C) a liquid medium.