N-(4-chlorophenyl)-2-methylpropionamidine | 643739-37-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-chlorophenyl)-2-methylpropionamidine
• 英文别名: N-(4-chlorophenyl)-2-methylpropanamidine；(1E)-N'-(4-Chlorophenyl)-2-methylpropanimidamide；N'-(4-chlorophenyl)-2-methylpropanimidamide
• CAS: 643739-37-1
• 化学式: C₁₀H₁₃ClN₂
• 分子量: 196.68
• InChiKey: BHELNTOOHWIXQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  38.4
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-methyl-4-phenylbut-3-yn-2-yl acetate 、 N-(4-chlorophenyl)-2-methylpropionamidine 在 dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 、 copper(II) acetate monohydrate 作用下， 以 甲醇 为溶剂， 反应 5.0h， 以52%的产率得到7-chloro-2-isopropyl-4-phenyl-5-(propan-2-ylidene)-5H-benzo[d][1,3]diazepine
  参考文献：
  名称：

  通过[5 + 2]环戊酰胺与N-芳基Ann环合成1,3-苯并二氮杂ze

  摘要：

  在本文中，提出了通过空前的[5 + 2] N-芳基am与炔丙基酯的环合反应，有效合成功能化1,3-苯并二氮杂pine的方法。反应通过Rh（III）催化的C（sp 2）-H链烯基化反应进行，然后进行环化和脱乙酰氧基化，以及级联的CH / N-H / C-O键断裂和C-C / C-N键形成。此外，测试了所选产品对几种人类癌细胞系的细胞毒性，证明了其在药物应用中的良好潜力。

  DOI：

  10.1021/acs.orglett.0c03515

文献信息

• Surface treatment liquid and hydrophilic treatment method
  申请人：Tokyo Ohka Kogyo Co., Ltd.

  公开号：US11066531B2

  公开（公告）日：2021-07-20

  An object is to provide a surface treatment liquid which can firmly bond, while coating the surface of a treatment target with an extremely thin film, a coating whose hydrophilicity is unlikely to be lowered even when the coating is brought into contact with fats and the like to the surface of the treatment target and a surface treatment method using the surface treatment liquid described above. In a surface treatment liquid containing a resin (A) and a solvent (S), as the resin (A), a resin is used which includes a constituent unit (a1) that includes an organic group including a quaternary ammonium cation group and having a sulfonic acid anion group at a terminal and that is derived from an N-substituted (meth) acrylamide, and includes a reactive silyl group in at least one of molecular chain terminals, the concentration of the resin (A) in the surface treatment liquid is less than 2 mass % and the pH of the surface treatment liquid is 4 or less.

  目的是提供一种表面处理液，该表面处理液可以在处理对象表面涂覆极薄的薄膜的同时，牢固地粘合处理对象表面的涂层，即使该涂层与脂肪等接触也不会降低亲水性，并提供一种使用上述表面处理液的表面处理方法。在含有树脂 (A) 和溶剂 (S) 的表面处理液中，作为树脂 (A)，使用了一种树脂，其组成单元 (a1) 包括一个有机基团，该有机基团包括一个季铵阳离子基团，其末端具有一个磺酸阴离子基团，该有机基团由 N-取代的（甲基）丙烯酰胺衍生而来、表面处理液中树脂 (A) 的浓度低于 2 质量%，表面处理液的 pH 值为 4 或更低。
• SURFACE TREATMENT LIQUID AND HYDROPHILIC TREATMENT METHOD
  申请人：Tokyo Ohka Kogyo Co., Ltd.

  公开号：EP3594252B1

  公开（公告）日：2022-06-01
• HYDROPHILIC TREATMENT METHOD AND SURFACE TREATMENT LIQUID
  申请人：Tokyo Ohka Kogyo Co., Ltd.

  公开号：EP3594253B1

  公开（公告）日：2022-06-01
• US9745406B2
  申请人：——

  公开号：US9745406B2

  公开（公告）日：2017-08-29
• [EN] IMAGE RECORDING METHOD<br/>[FR] PROCEDE D'ENREGISTREMENT D'IMAGE
  申请人：CANON FINETECH INC

  公开号：WO2004067287A1

  公开（公告）日：2004-08-12

  An image recording method is disclosed. To form an image, an ink is caused to adhere on a recording medium which is provided with at least one ink-receiving layer on a base material. The ink is an inkjet recording ink, which is composed of a high-molecular dispersant, a water-insoluble colorant, a water-soluble organic solvent and water. The high-molecular dispersant contains at least one hydrophobic block and at least one hydrophilic block. The ink-receiving layer contains fine inorganic particles and a water-soluble resin and/or water-dispersible resin, and a surface pH of the ink-receiving layer is controlled within a range of from 3.0 to 6.5.