N-(4-乙烯基苄基)亚胺二乙酸 | 46917-20-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N-(4-乙烯基苄基)亚胺二乙酸
• 中文别名: N-((4-乙烯基苄基)氨叉基)二乙酸；2,2'-((4-乙烯基苄基)氨叉基)二乙酸
• 英文名称: N-(4-vinyl)-benzyl iminodiacetic acid
• 英文别名: 4-vinylbenzylimino diacetic acid；p-vinylbenzyliminodiacetic acid；Glycine, N-(carboxymethyl)-N-[(4-ethenylphenyl)methyl]-；2-[carboxymethyl-[(4-ethenylphenyl)methyl]amino]acetic acid
• CAS: 46917-20-8
• 化学式: C₁₃H₁₅NO₄
• 分子量: 249.266
• InChiKey: UBGQOSNFVJFTLZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  77.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-氯甲基苯乙烯 、 iminodiacetic acid disodium salt 以 乙醇 、 水 为溶剂， 反应 72.0h， 以39%的产率得到N-(4-乙烯基苄基)亚胺二乙酸
  参考文献：
  名称：

  Polyfunctional sorbent materials

  摘要：

  本文揭示了一种材料，包括功能化固体支撑表面，其中功能化包括与支撑表面结合的硫代烯烃链和硫代烯烃链与源自配体的基团偶联，其中配体包括末端烯基和至少一个第一功能基团，配置为与至少一个预定目标物种结合。

  公开号：

  US10315185B2

文献信息

• STABLE SOLID FINGOLIMOD DOSAGE FORMS
  申请人：Handa Pharmaceuticals, LLC

  公开号：US20160206557A1

  公开（公告）日：2016-07-21

  The present invention relates to a solid pharmaceutical dosage forms and methods for preparing the solid pharmaceutical dosage form that contains fingolimod or its pharmaceutically acceptable salts, conjugates or complexes thereof. The solid pharmaceutical dosage forms may rapidly disintegrates in a patient's oral cavity.

  本发明涉及固体药物剂型及制备含有非格列酮或其药用可接受的盐、结合物或复合物的固体药物剂型的方法。这些固体药物剂型可能在患者口腔中迅速分解。
• Organic fluid gelifying compound
  申请人：Vallieres, Lucien

  公开号：EP0839539A1

  公开（公告）日：1998-05-06

  The compound of the invention comprises a combination of four ingredients: a superabsorbent polymer, particularly sodium polyacrylate; a chemical disinfectant, particularly potassium peroxymonosulfate; an organic deodorant, particularly from herbal extracts; and a chelating agent, particularly malic acid. This blood gelifying compound can be used by medical staff in surgery rooms and the like, when wasted blood from the patient is collected in waste bags, to solidify the fluid inside the bag so as to prevent accidental leaks and contamination. Urine or blood spills, which are often accidentally spilled on the hospital floors, can also be recuperated and disposed of in a timely fashion with the present compound, so as not to compromise the hygienic integrity of the hospital.

  本发明的化合物由四种成分组合而成：一种超吸收聚合物，特别是聚丙烯酸钠；一种化学消毒剂，特别是过一硫酸钾；一种有机除臭剂，特别是草药提取物；以及一种螯合剂，特别是苹果酸。当病人的废血被收集到废物袋中时，医护人员可以在手术室等地方使用这种血液凝胶化合 物，使袋中的液体凝固，以防止意外泄漏和污染。医院地板上经常不小心洒落的尿液或血液也可以用本化合物及时回收和处理，以免影响医院的卫生完整性。
• Imprints formed using functionally complemetary monomers
  申请人：MOSBACH, Klaus

  公开号：EP0982591A2

  公开（公告）日：2000-03-01

  This patent application describes the use of molecular imprinting as a means for preparation of anti-idiotypic imprint matrices. With this technique, imprints of artificial or natural molecules including their recognition sites, such as of molecularly imprinted polymers or biological receptors, antibodies or enzymes, can be prepared. In the former case, using the original imprints as casts or molds in a subsequent polymerisation step, utilising preferentially functionally complementary monomers, the formation of imprint materials containing recognition sites complementary in shape and functionality with the original imprint can be obtained but being of different composition. Alternatively, imprints or images of the artificial or biological species can be obtained directly. The so formed preparations can be used in a vast variety of appolications, e.g. as new drugs, inhibitors or new affinity materials.

  本专利申请介绍了利用分子印迹技术制备抗生物体印迹基质的方法。利用这项技术，可以制备人工或天然分子的印迹，包括它们的识别位点，如分子印迹聚合物或生物受体、抗体或酶。在前一种情况下，在随后的聚合步骤中使用原始印迹作为铸模或模具，优先使用功能互补的单体，可以获得含有识别位点的印迹材料，这些识别位点在形状和功能上与原始印迹互补，但组成不同。或者，也可以直接获得人工或生物物种的印记或图像。这样形成的制剂可用于多种用途，如作为新药物、抑制剂或新的亲和材料。
• Methods for enhancing the metal removal rate during the chemical-mechanical polishing process of a semiconductor
  申请人：SIEMENS AKTIENGESELLSCHAFT

  公开号：EP1011131A1

  公开（公告）日：2000-06-21

  A method for enhancing the removal rate of a metal barrier layer during CMP includes providing a semiconductor wafer having an insulator layer, a metal barrier layer formed on at least a portion of the insulation layer and a conductive layer formed thereon and contacting the semiconductor wafer with a chemical-mechanical polishing slurry containing a metal removal-enhancing amount of at least one chelating agent.

  一种在 CMP 期间提高金属阻挡层去除率的方法，包括提供具有绝缘层、在绝缘层至少一部分上形成的金属阻挡层以及在其上形成的导电层的半导体晶片，并将半导体晶片与含有至少一种螯合剂的提高金属去除量的化学机械抛光浆料接触。
• Improved recovery and transportation of heavy crude oils
  申请人：ROHM AND HAAS COMPANY

  公开号：EP1033471A1

  公开（公告）日：2000-09-06

  Novel amine-chelate complexes are useful in significantly reducing the viscosity of heavy crude oils, facilitating the recovery and transportation of such heavy crude oils. The amine-chelate complexes are formed by heating together an organic amine with a chelating agent.

  新型胺螯合物可显著降低重质原油的粘度，促进重质原油的回收和运输。胺螯合物是通过加热有机胺和螯合剂而形成的。