methyl ester of 4-butylcyclohexanecarboxylic acid | 344411-87-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl ester of 4-butylcyclohexanecarboxylic acid
• 英文别名: methyl 4-butylcyclohexanecarboxylate；Cyclohexanecarboxylic acid, 4-butyl-, methyl ester, trans-；methyl 4-butylcyclohexane-1-carboxylate
• CAS: 344411-87-6
• 化学式: C₁₂H₂₂O₂
• mdl: MFCD12177758
• 分子量: 198.305
• InChiKey: VVOVPJQHZJFLMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.916
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  methyl ester of 4-butylcyclohexanecarboxylic acid 生成 对丁基环已烷甲酸
  参考文献：
  名称：

  ACOSTA, C. K.;CESSAC, J. W.;RAO, PEMMARAJU N.;KIM, HYUN K., J. LABELL. COMPOUNDS AND RADIOPHARM., 28,(1990) N0, C. 1201-1212

  摘要：

  DOI：
• 作为产物：
  描述：

  methyl 4-butylcyclohex-2-ene-1-carboxylate 生成 methyl ester of 4-butylcyclohexanecarboxylic acid
  参考文献：
  名称：

  ACOSTA, C. K.;CESSAC, J. W.;RAO, PEMMARAJU N.;KIM, HYUN K., J. LABELL. COMPOUNDS AND RADIOPHARM., 28,(1990) N0, C. 1201-1212

  摘要：

  DOI：

文献信息

• [EN] CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF<br/>[FR] ACIDES CARBOXYLIQUES CONTENANT UN CYCLOALKYLE ET LEURS UTILISATIONS
  申请人：LIMINAL BIOSCIENCES LTD

  公开号：WO2021124272A1

  公开（公告）日：2021-06-24

  The present application discloses a compound of formula (I) or a salt thereof: (I) and compositions comprising such compound or salt thereof. The use of such compound, salt thereof or composition comprising same for treating anemia or leukopenia, fibrosis, cancer, hypertension and/or a metabolic condition in a subject is also disclosed.

  本申请公开了化合物的结构式(I)或其盐：(I)，以及包含该化合物或其盐的组合物。还公开了利用该化合物、其盐或包含相同成分的组合物治疗受试者的贫血或白细胞减少症、纤维化、癌症、高血压和/或代谢状况的用途。
• Methods and compositions of treating a flaviviridae family viral infection
  申请人：Einav Shirit

  公开号：US20100015093A1

  公开（公告）日：2010-01-21

  Briefly described, embodiments of this disclosure include compounds, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3′UTR of HCV negative strand RNA in a host, methods of treating liver fibrosis in a host, and the like.

  简要概述，本公开的实施例包括化合物、药物组合物、治疗感染黄病毒科病毒的宿主的方法、抑制宿主中HCV复制的方法、抑制NS4B多肽与HCV负链RNA的3′UTR结合的方法、治疗宿主肝纤维化的方法等。
• METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION
  申请人：Glenn Jeffrey S.

  公开号：US20120148534A1

  公开（公告）日：2012-06-14

  Briefly described, embodiments of this disclosure include compounds, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3′UTR of HCV negative strand RNA in a host, methods of treating liver fibrosis in a host, and the like.

  简单地说，本公开的实施例包括化合物、药物组合物、治疗感染黄病毒科病毒的宿主的方法、抑制宿主中HCV复制的方法、抑制NS4B多肽与HCV负链RNA的3'UTR结合的方法、治疗宿主肝纤维化的方法等。
• POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER
  申请人：Nose Sayaka

  公开号：US20130116396A1

  公开（公告）日：2013-05-09

  The present invention relates to materials used for aligning liquid crystals of liquid crystal display elements and to a polymer for use in liquid crystal vertical alignment layer used in producing a liquid crystal vertical alignment layer. The polymer for use in a liquid crystal vertical alignment layer includes (a) a moiety that is photochemically isomerizable but not photochemically crosslinked, (b) a moiety that is photochemically crosslinkable, and (c) a moiety that stabilizes a vertical alignment. The polymer can be used to produce a vertical alignment layer that has a liquid crystal alignment property enabling control of alignment at a low UV dose and that offers a large pretilt angle and superior optical stability.

  本发明涉及用于对齐液晶显示元件的材料，以及用于制造液晶垂直对齐层的液晶垂直对齐层聚合物。用于液晶垂直对齐层的聚合物包括（a）具有光化学异构性但不具有光化学交联的基团，（b）具有光化学交联性的基团，以及（c）稳定垂直对齐的基团。该聚合物可用于制造具有液晶对齐性能的垂直对齐层，使得在低紫外线剂量下能够控制对齐，并提供大的预倾角和优异的光学稳定性。
• COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF
  申请人：Schadt Martin

  公开号：US20140221574A1

  公开（公告）日：2014-08-07

  Provided is a liquid crystal alignment layer of which a constituent member is a polymer represented by the general formula (I).

  提供的是一种液晶取向层，其中成分之一是由通式（I）表示的聚合物。