N-(4-hydroxyphenyl)-4-prop-2-enoxybenzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-hydroxyphenyl)-4-prop-2-enoxybenzamide
• 化学式: C₁₆H₁₅NO₃
• 分子量: 269.3
• InChiKey: OVMUPAADTDFJJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对羟基苯甲酸 在 氯化亚砜 、 三乙胺 、 potassium iodide 、 potassium hydroxide 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 、 丙酮 、 甲苯 为溶剂， 反应 5.5h， 生成 N-(4-hydroxyphenyl)-4-prop-2-enoxybenzamide
  参考文献：
  名称：

  Synthesis of Amide-Type Smectic A Side-Chain Polysiloxane Liquid Crystal

  摘要：

  In this paper, monomer N-(4-hydroxyphenyl-1) 4-alkyloxybenzamide was obtained by the Williamson reaction, acylation, and aminolysis. Side-chain polysiloxane liquid crystal was then successfully synthesized by a grafting reaction of the monomer. The monomer and liquid crystal were characterized by Fourier-transform infrared spectroscopy, 1H nuclear magnetic resonance spectroscopy, differential scanning calorimetry, and polarization microscopy. The results showed that both monomer and polymer exhibited thermotropic smectic A behavior, and they were very stable within the studied temperature range. They may be very sensitive to both electric and magnetic fields because of their liquid crystalline properties.

  DOI：

  10.1080/15421406.2012.708309

文献信息

• New derivatives of 1-alkylamine-(4(p-alkyloxy-benzamide)phenoxy)-2-propanol, having beta-sympatholytic activity, their salts, and production processes thereof
  申请人：A. Menarini S.a.S.

  公开号：EP0100051B1

  公开（公告）日：1986-04-09
• US4503075A
  申请人：——

  公开号：US4503075A

  公开（公告）日：1985-03-05