4-Ethylamino-thiophenol | 4946-23-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 英文名称: 4-Ethylamino-thiophenol
• 英文别名: 4-(Ethylamino)benzenethiol
• CAS: 4946-23-0
• 化学式: C₈H₁₁NS
• 分子量: 153.248
• InChiKey: OMUSVLUXQOYBJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  13
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Ethylamino-thiophenol 在 sodium iodide sodium hydroxide 、 sodium carbonate 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 48.0h， 生成 N-ethyl-4-[3-[4-(2-methylphenyl)piperazin-1-yl]propylsulfanyl]aniline
  参考文献：
  名称：

  降压的1- [3-（4-取代的苯硫基）丙基] -4-（取代的苯基）哌嗪的合成和QSAR研究。

  摘要：

  合成了一系列1- [3-（4-取代的苯硫基）丙基] -4-（取代的苯基）哌嗪，并对其降压活性进行了评估。QSAR研究表明，芳基取代基的共振和疏水参数对降压活性很重要。共振参数在描述这些化合物的5-HT（2A）受体结合亲和力变化中的相似作用表明5-HT（2A）受体在介导标题化合物的降压作用中可能发挥作用。

  DOI：

  10.1016/j.bmcl.2006.12.072

文献信息

• PHTHALOCYANINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP1482013A1

  公开（公告）日：2004-12-01

  A phthalocyanine compound represented by the following general formula (I) and the mixture thereof, and an optical recording medium containing the compound/mixture in its recording layer. wherein in formula (I), M is two hydrogen atoms, a divalent metal atom, a mono-substituted trivalent metal atom, a di-substituted tetravalent metal atom, or an oxymetal, and L1, L2, L3 and L4 are each independently formula (a), formula (b), or formula (c) : in formula (a), formula (b), and formula (c), X represents a substituted or unsubstituted alkyl group, alkoxy group, alkylthio group, aryloxy group, and arylthio group, Rs are each independently a hydrogen atom, a substituted or unsubstituted alkyl group with 1-6 of total carbon numbers, a substituted or unsubstituted aryl group with 6-10 of total carbon numbers, A represents a carbonyl group, a thiocarbonyl group, a sulfone group, a sulfine group, or a carboimidoyl group, Y represents a metal compound residue, and Z represents independently a hydrogen atom, a nitro group, or a halogen atom, and at least one of L1-L4 is formula (a) or (b).

  由以下通式(I)表示的酞菁化合物及其混合物，以及在其记录层中含有该化合物/混合物的光学记录介质。 其中，在式 (I) 中，M 是两个氢原子、二价金属原子、一取代三价金属原子、二取代四价金属原子或氧金属；L1、L2、L3 和 L4 各自独立地为式 (a)、式 (b) 或式 (c) ： 在式(a)、式(b)和式(c)中，X 代表取代或未取代的烷基、烷氧基、烷硫基、芳氧基和芳硫基，Rs 各自独立地为氢原子、总碳数为 1-6 的取代或未取代的烷基、A 代表羰基、硫代羰基、砜基、硫基或羧酰亚胺基，Y 代表金属化合物残基，Z 独立地代表氢原子、硝基或卤素原子，L1-L4 中至少有一个是式 (a) 或 (b)。
• PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ADSORBED ELECTRODE, AND METHOD FOR PRODUCING DYE-SENSITIZED SOLAR CELL
  申请人：FUJIFILM CORPORATION

  公开号：EP2933875B1

  公开（公告）日：2017-03-29
• Phthalocyanine compound, process for producing the same, and optical recording medium containing the same
  申请人：Seino Kazuhiro

  公开号：US20050201265A1

  公开（公告）日：2005-09-15

  A phthalocyanine compound represented by the following general formula (I) and the mixture thereof, and an optical recording medium containing the compound/mixture in its recording layer. wherein in formula (I), M is two hydrogen atoms, a divalent metal atom, a mono-substituted trivalent metal atom, a di-substituted tetravalent metal atom, or an oxymetal, and L 1 , L 2 , L 3 and L 4 are each independently formula (a), formula (b), or formula (c): wherein X, Y, Z and R are defined.
• SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES
  申请人：ZYMEWORKS INC.

  公开号：US20170029490A1

  公开（公告）日：2017-02-02

  Sulfonamide-containing linkage systems for release of payload compounds from an attached targeting moiety in drug conjugates. The conjugates have the formula of [(P)-(L)]m-(T), wherein (P) is a payload compound, (L) is a linker, (T) is a targeting moiety and m is an integer from 1- to 10. Also provided are pharmaceutical compositions comprising such conjugates and there use in treating cancer.
• US7332261B2
  申请人：——

  公开号：US7332261B2

  公开（公告）日：2008-02-19