3-[2-[2-[2-(1H-indol-3-ylsulfanyl)ethoxy]ethoxy]ethylsulfanyl]-1H-indole | 1186467-86-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-[2-[2-[2-(1H-indol-3-ylsulfanyl)ethoxy]ethoxy]ethylsulfanyl]-1H-indole
• CAS: 1186467-86-6
• 化学式: C₂₂H₂₄N₂O₂S₂
• 分子量: 412.577
• InChiKey: QXALTYZQZYICAB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  28
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  (1H-吲哚-3-基磺酰基)盐酸乙脒碘化氢 、 三聚乙二醇二甲烷磺酸酯 在 sodium hydroxide 作用下， 以 甲醇 、 水 为溶剂， 反应 0.17h， 生成 3-[2-[2-[2-(1H-indol-3-ylsulfanyl)ethoxy]ethoxy]ethylsulfanyl]-1H-indole
  参考文献：
  名称：

  Synthesis and characterization of novel indole-containing half-crowns as new emissive metal probes

  摘要：

  Two new indole derivatives have been synthesized by a one-pot procedure and their potential as fluorescence probes for metal ions was investigated. The sensor capability of 1 and 2 toward cations such as Ag+, Cu2+ Zn2+, Cd2+, Pb2+, and Hg2- was studied in dichloromethane solution by absorption, fluorescence emission, and H-1 NMR titrations. Both probes showed selectivity for Ag+ and Hg2+ ions. The results suggest that these compounds may serve as promising models for future design of novel and more potent sensors. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.073