2-(3,4-dimethoxyphenyl)-3-nitropyridine | 663918-37-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(3,4-dimethoxyphenyl)-3-nitropyridine
• CAS: 663918-37-4
• 化学式: C₁₃H₁₂N₂O₄
• 分子量: 260.249
• InChiKey: NMBSJFKOENPUFG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  77.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-(3,4-dimethoxyphenyl)-3-nitropyridine 在 platinum on carbon 氢气 作用下， 以 乙醇 为溶剂， 反应 4.0h， 生成 2-(3,4-dimethoxyphenyl)pyridin-3-amine
  参考文献：
  名称：

  PHENYLPYRIDINE COMPOUND AND BACTERICIDAL COMPOSITION CONTAINING THE SAME

  摘要：

  该式代表的苯基吡啶化合物对植物病害具有优异的控制活性: [其中，在该式中，R1、R2、R3、R4和R5分别代表氢原子、卤原子等; R6代表氢原子或C1-C3烷基; R7、R8和R11分别代表氢原子、卤原子等; R9和R10分别代表羟基等; W1―W2=W3―W4代表N―CH=CH―CH等; X代表氧原子等; Q代表(C1-C6烷氧基)亚甲基等]。

  公开号：

  EP1541557A1
• 作为产物：
  描述：

  2-氯-3-硝基吡啶 、 3,4-二甲氧基苯硼酸 在 PdCl₂(1,1′-bis(diphenylphosphino)ferrocene)*2(dichloromethane) potassium phosphate 作用下， 以 乙二醇二甲醚 为溶剂， 反应 4.0h， 生成 2-(3,4-dimethoxyphenyl)-3-nitropyridine
  参考文献：
  名称：

  PHENYLPYRIDINE COMPOUND AND BACTERICIDAL COMPOSITION CONTAINING THE SAME

  摘要：

  该式代表的苯基吡啶化合物对植物病害具有优异的控制活性: [其中，在该式中，R1、R2、R3、R4和R5分别代表氢原子、卤原子等; R6代表氢原子或C1-C3烷基; R7、R8和R11分别代表氢原子、卤原子等; R9和R10分别代表羟基等; W1―W2=W3―W4代表N―CH=CH―CH等; X代表氧原子等; Q代表(C1-C6烷氧基)亚甲基等]。

  公开号：

  EP1541557A1

文献信息

• Phenylpyridine compound and fungicidal compostion containing the same
  申请人：Komori Takashi

  公开号：US20060041144A1

  公开（公告）日：2006-02-23

  A phenylpyridine compound represented by the formula has an excellent controlling activity against plant diseases: [, wherein, in the formula, R 1 , R 2 , R 3 , R 4 and R 5 independently represent a hydrogen atom, a halogen atom and the like; R 6 represents a hydrogen atom or a C1-C3 alkyl group; R 7 , R 8 and R 11 independently represent a hydrogen atom, a halogen atom and the like; R 9 and R 10 independently represent a hydroxyl group and the like; W 1 —W 2 ═W 3 —W 4 represents N—CH═CH—CH and the like; X represents an oxygen atom and the like; and Q represents a (C1-C6 alkoxy)methylene and the like].

  一种苯基吡啶化合物，其化学式如下，在该式中，R1、R2、R3、R4和R5独立地表示氢原子、卤素原子等；R6表示氢原子或C1-C3烷基；R7、R8和R11独立地表示氢原子、卤素原子等；R9和R10独立地表示羟基等；W1-W2═W3-W4表示N-CH═CH-CH等；X表示氧原子等；Q表示(C1-C6烷氧基)亚甲基等。该化合物对植物病害具有优异的控制活性。
• PHENYLPYRIDINE COMPOUND AND BACTERICIDAL COMPOSITION CONTAINING THE SAME
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1541557A1

  公开（公告）日：2005-06-15

  A phenylpyridine compound represented by the formula has an excellent controlling activity against plant diseases: [, wherein, in the formula, R1, R2, R3, R4 and R5 independently represent a hydrogen atom, a halogen atom and the like; R6 represents a hydrogen atom or a C1-C3 alkyl group; R7, R8 and R11 independently represent a hydrogen atom, a halogen atom and the like; R9 and R10 independently represent a hydroxyl group and the like; W1―W2=W3 ―W4 represents N―CH=CH―CH and the like; X represents an oxygen atom and the like; and Q represents a (C1-C6 alkoxy)methylene and the like].

  该式代表的苯基吡啶化合物对植物病害具有优异的控制活性: [其中，在该式中，R1、R2、R3、R4和R5分别代表氢原子、卤原子等; R6代表氢原子或C1-C3烷基; R7、R8和R11分别代表氢原子、卤原子等; R9和R10分别代表羟基等; W1―W2=W3―W4代表N―CH=CH―CH等; X代表氧原子等; Q代表(C1-C6烷氧基)亚甲基等]。
• Solvent-free synthesis of δ-carbolines/carbazoles from 3-nitro-2-phenylpyridines/2-nitrobiphenyl derivatives using DPPE as a reducing agent
  作者：Haixia Peng、Xuxing Chen、Yanhong Chen、Qian He、Yuyuan Xie、Chunhao Yang

  DOI：10.1016/j.tet.2011.06.027

  日期：2011.8

  A green and efficient preparation of functionalized delta-carbolines/carbazoles via reductive ring closure by 1,2-bis(dipenylphosphino)ethane under solvent-free conditions is described. The starting materials 3-nitro-2-phenylpyridines/2-nitrobiphenyl derivatives are readily prepared through Suzuki-Miyaura cross-coupling reaction from commercially available compounds. And the polar by-product ethane-1,2-diylbis(diphenylphosphine oxide) is easily removed from the relatively polar reaction mixture. Various substituted delta-carbolines/carbazoles are obtained in acceptable yields. It is particularly worth mentioning that substrates with electron-withdrawing groups (EWG) also give the desired products in good yield. (C) 2011 Elsevier Ltd. All rights reserved.