N-[3-(二甲基氨基)丙基]-D-谷氨酰胺 | 51812-79-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: N-[3-(二甲基氨基)丙基]-D-谷氨酰胺
• 中文别名: N-[3-(二甲氨基)丙基]-D-葡萄酰胺
• 英文名称: N-(3-(dimethylamino)propyl)-D-gluconamide
• 英文别名: 3-Dimethylaminopropyl Gluconamide；(2R,3S,4R,5R)-N-[3-(dimethylamino)propyl]-2,3,4,5,6-pentahydroxyhexanamide
• CAS: 51812-79-4
• 化学式: C₁₁H₂₄N₂O₆
• 分子量: 280.321
• InChiKey: ZRQLLXVNSJXTAP-DOLQZWNJSA-N

物化性质

• 沸点：
  630.7±55.0 °C(Predicted)
• 密度：
  1.320±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  134
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  N,N-二甲基-1,3-二氨基丙烷 、 葡萄糖酸内酯 以 甲醇 为溶剂， 反应 6.0h， 以70%的产率得到N-[3-(二甲基氨基)丙基]-D-谷氨酰胺
  参考文献：
  名称：

  Synthesis and evaluation of d-gluconamides as green mineral scales

  摘要：

  A series of 13 D-gluconamides were synthesized in moderate to good yields and evaluated as green scale inhibitors. The crystal structures of two compounds were determined by X-ray crystallography. The compounds 6c and 6d showed a reasonable inhibition of BaSO4 precipitation from aqueous solution (47% and 51%, respectively) that indicated the potential for these derivatives of delta-gluconolactone. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2012.01.027

文献信息

• Additives and products including oligoesters
  申请人：——

  公开号：US20030199593A1

  公开（公告）日：2003-10-23

  The present invention relates to oligoesters and their use or the creation of additives. Oligoester containing additives and/or oligoesters themselves may be used for formulating pharmaceutical preparations, cosmetics or personal care products such as shampoos and conditioners. These oligoesters are particularly useful for the creation of multi-purpose additives that can impart conditioning, long substantivity and/or UV protection. Individual oligoesters and oligoester mixtures are described.

  本发明涉及寡酯及其用途或添加剂的制备。含有寡酯的添加剂和/或寡酯本身可用于配制药物制剂、化妆品或个人护理产品，如洗发水和护发素。这些寡酯对于制备能够赋予调理、长效性和/或紫外线保护的多功能添加剂特别有用。描述了单独的寡酯和寡酯混合物。
• Additives and products includings oligoesters
  申请人：Pereira Abel G.

  公开号：US20100035999A1

  公开（公告）日：2010-02-11

  The present invention relates to oligoesters and their use for the creation of additives. Oligoester containing additives and/or oligoesters themselves may be used for formulating pharmaceutical preparations, cosmetics or personal care products such as shampoos and conditioners. These oligoesters are particularly useful for the creation of multi-purpose additives that can impart conditioning, long substantivity and/or UV protection. Individual oligoesters and oligoester mixtures are described.

  本发明涉及寡聚酯及其用于创建添加剂的使用。含有寡聚酯的添加剂和/或寡聚酯本身可用于制定制药制剂、化妆品或个人护理产品，如洗发水和护发素。这些寡聚酯特别适用于创建多功能添加剂，可以赋予调理、长效性和/或紫外线保护。描述了单个寡聚酯和寡聚酯混合物。
• ADDITIVES AND PRODUCTS INCLUDING OLIGOESTERS
  申请人：Croda, Inc.

  公开号：EP1469813A2

  公开（公告）日：2004-10-27
• EP1469813A4
  申请人：——

  公开号：EP1469813A4

  公开（公告）日：2008-08-27
• US4038294A
  申请人：——

  公开号：US4038294A

  公开（公告）日：1977-07-26