α-Isopropylamino-buttersaeure | 89855-39-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: α-Isopropylamino-buttersaeure
• 英文别名: 2-[(Propan-2-yl)amino]butanoic acid；2-(propan-2-ylamino)butanoic acid
• CAS: 89855-39-0
• 化学式: C₇H₁₅NO₂
• mdl: MFCD12048418
• 分子量: 145.202
• InChiKey: ZRQOLCFROPHFOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  α-Isopropylamino-buttersaeure 在 盐酸 、 sodium nitrite 作用下， 生成 N-Nitroso-α-isopropylamino-buttersaeure
  参考文献：
  名称：

  肼酸。二。烷基-，芳基-和羟基-α-肼基酸。

  摘要：

  DOI：

  10.1021/jm00332a021
• 作为产物：
  描述：

  2-溴丁酸 、 异丙胺 以 水 为溶剂， 生成 α-Isopropylamino-buttersaeure
  参考文献：
  名称：

  肼酸。二。烷基-，芳基-和羟基-α-肼基酸。

  摘要：

  DOI：

  10.1021/jm00332a021

文献信息

• Alkoxy indolinone based protein kinase inhibitors
  申请人：Liang Congxin

  公开号：US20070072934A1

  公开（公告）日：2007-03-29

  Alkoxy indolinone based acid and amide derivatives have enhanced and unexpected drug properties as inhibitors of protein kinases and are useful in treating disorders related to abnormal protein kinase activities such as cancer.

  基于Alkoxy吲哚酮的酸和酰胺衍生物具有增强和意想不到的药物特性，可作为蛋白激酶抑制剂，并可用于治疗与异常蛋白激酶活性相关的疾病，如癌症。
• Viral Polymerase Inhibitors
  申请人：Beaulieu Louis Pierre

  公开号：US20070142380A1

  公开（公告）日：2007-06-21

  An isomer, enantiomer, diastereoisomer or tautomer of a compound, represented by formula I: wherein A, B, R 2 , R 3 , L, M 1 , M 2 , M 3 , M 4 , Y 1 , Y 0 , Z and Sp are as defined in claim 1 , or a salt thereof, as an inhibitor of HCV NS5B polymerase.

  一种化合物的同分异构体、对映异构体、非对映异构体或互变异构体，其化学式为I：其中A、B、R2、R3、L、M1、M2、M3、M4、Y1、Y0、Z和Sp如权利要求1所定义，或其盐，作为HCV NS5B聚合酶的抑制剂。
• Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds
  申请人：Arimilli N. Murty

  公开号：US20070010489A1

  公开（公告）日：2007-01-11

  Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit 5 HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.

  本发明揭示了具有HIV蛋白酶抑制剂性质的膦酸酯取代化合物，其具有作为治疗剂和其他工业用途的用途。该组合物抑制5型HIV蛋白酶活性和/或在治疗艾滋病和其他抗病毒感染方面具有治疗作用，以及在检测HIV蛋白酶方面的检测中有用。
• ANTI-INFECTIVE PHOSPHONATE ANALOGS
  申请人：Boojamra Constantine G.

  公开号：US20080167270A1

  公开（公告）日：2008-07-10

  The invention is related to phosphorus substituted anti-infective compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
• PROCESS FOR POLYMERISATION OF ETHYLENE
  申请人：Aliyev Vugar O.

  公开号：US20130310245A1

  公开（公告）日：2013-11-21

  The present invention is directed to a process for the production of high density polyethylene by polymerisation of ethylene in the presence of a supported chromium oxide based catalyst which is modified with an organic compound comprising oxygen and a nitrogen atom which is selected from the group consisting of saturated heterocyclic organic compounds with a five or six membered ring, amino esters and amino alcohols. Such organic compounds allow manufacturing of HDPE with increases molecular weight distribution and increased molecular weight.