N-[4-[3,7-二(叔-丁基)-(4H)-1,2-重氮基庚英-5-基]苯基]二苯甲基胺 | 171868-16-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 中文名称: N-[4-[3,7-二(叔-丁基)-(4H)-1,2-重氮基庚英-5-基]苯基]二苯甲基胺
• 英文名称: (3R,4R)-Pyrrolidine-3,4-diamine
• CAS: 171868-16-9
• 化学式: C₄H₁₁N₃
• 分子量: 101.151
• InChiKey: WCOQAGPRGRKKLM-QWWZWVQMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  64.1
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-[4-[3,7-二(叔-丁基)-(4H)-1,2-重氮基庚英-5-基]苯基]二苯甲基胺 、 右旋樟脑-10-磺酰氯 在 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以90%的产率得到
  参考文献：
  名称：

  Asymmetric Addition of Diethylzinc to Ketones promoted by Tartaric Acid Derivatives

  摘要：

  The preparation of new sulfonamide ligands derived from L-tartaric acid and camphor sulfonyl chloride are described. The employment in the titanium tetraisopropoxide-promoted enantioselective addition of diethylzinc to ketones has been studied. The best enantiomeric excess is up to 99% with 7mol% catalyst loading at room temperature.

  DOI：

  10.1080/00397910802139304
• 作为产物：
  描述：

  在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 以100%的产率得到N-[4-[3,7-二(叔-丁基)-(4H)-1,2-重氮基庚英-5-基]苯基]二苯甲基胺
  参考文献：
  名称：

  Asymmetric Addition of Diethylzinc to Ketones promoted by Tartaric Acid Derivatives

  摘要：

  The preparation of new sulfonamide ligands derived from L-tartaric acid and camphor sulfonyl chloride are described. The employment in the titanium tetraisopropoxide-promoted enantioselective addition of diethylzinc to ketones has been studied. The best enantiomeric excess is up to 99% with 7mol% catalyst loading at room temperature.

  DOI：

  10.1080/00397910802139304

文献信息

• Asymmetric Addition of Diethylzinc to Ketones promoted by Tartaric Acid Derivatives
  作者：Ailing Hui、Jintang Zhang、Zhiyong Wang

  DOI：10.1080/00397910802139304

  日期：2008.6.27

  The preparation of new sulfonamide ligands derived from L-tartaric acid and camphor sulfonyl chloride are described. The employment in the titanium tetraisopropoxide-promoted enantioselective addition of diethylzinc to ketones has been studied. The best enantiomeric excess is up to 99% with 7mol% catalyst loading at room temperature.