苯酰胺,2,3-二氨基-,盐酸(1:2) | 3006-63-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 中文名称: 苯酰胺,2,3-二氨基-,盐酸(1:2)
• 中文别名: (3R,4S,5R)-3,4,5-三羟基-6-膦酰氧基己酸
• 英文名称: 2-Deoxy-D-arabino-hexonsaeure-6-phosphat
• 英文别名: 2-Deoxy-6-phosphogluconate；(3R,4S,5R)-3,4,5-trihydroxy-6-phosphonooxyhexanoic acid
• CAS: 3006-63-1
• 化学式: C₆H₁₃O₉P
• 分子量: 260.138
• InChiKey: LTHDIZOWAIGONP-KODRXGBYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  Phosphoric acid mono-((2R,3S,4R,6R)-3,4-dihydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl) ester; compound with cyclohexylamine 生成 苯酰胺,2,3-二氨基-,盐酸(1:2)
  参考文献：
  名称：

  2-Deoxy-D-arabino-hexonic Acid 6-Phosphate and Methyl 2-Deoxy-β-D-arabino-hexopyranoside 4,6-(Monophenyl phosphate)

  摘要：

  DOI：

  10.1021/jo01035a053

文献信息

• Enzymes
  申请人：Chawla K. Narinder

  公开号：US20050118594A1

  公开（公告）日：2005-06-02

  Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode-ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.

  本发明的各种实施例提供了人类酶（ENZM）和识别并编码ENZM的多核苷酸。本发明的实施例还提供表达载体、宿主细胞、抗体、激动剂和拮抗剂。其他实施例提供了诊断、治疗或预防与ENZM异常表达相关的疾病的方法。
• Oxidoreductases
  申请人：——

  公开号：US20040054157A1

  公开（公告）日：2004-03-18

  The invention provides human oxidoreductases (OXRD) and polynucleotides which identify and encode OXRD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of OXRD.

  本发明提供了人类氧化还原酶（OXRD）和能够识别和编码OXRD的多核苷酸。本发明还提供了表达载体、宿主细胞、抗体、激动剂和拮抗剂。本发明还提供了诊断、治疗或预防与OXRD异常表达相关的疾病的方法。
• OXIDOREDUCTASES
  申请人：Incyte Genomics, Inc.

  公开号：EP1320585A2

  公开（公告）日：2003-06-25
• ENZYMES
  申请人：Incyte Genomics, Inc.

  公开号：EP1360304A2

  公开（公告）日：2003-11-12
• Preparation for the application of agents in mini-droplets
  申请人：Cevc Gregor

  公开号：US20070042030A1

  公开（公告）日：2007-02-22

  The invention relates to a preparation for the application of agents in the form of minuscule droplets of fluid, in particular provided with membrane-like structures consisting of one or several layers of amphiphilic molecules, or an amphiphilic carrier substance, in particular for transporting the agent into and through natural barriers such as skin and similar materials. The preparation contains a concentration of edge active substances which amounts to up to 99 mol-% of the agent concentration which is required for the induction of droplet solubilization. Such preparations are suitable, for example, for the non-invasive applications of antidiabetics, in particular of insulin. The invention, moreover, relates to the methods for the preparation of such formulations.