4-Methoxy-benzenetellurol | 743364-44-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-Methoxy-benzenetellurol
• 英文别名: 4-methoxybenzenetellurol
• CAS: 743364-44-5
• 化学式: C₇H₈OTe
• 分子量: 235.74
• InChiKey: QLHKKCXDOVKWLT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.22
• 重原子数：
  9.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  1,3-二溴丙烷 、 4-Methoxy-benzenetellurol 生成 1-(3-Bromo-propyltellanyl)-4-methoxy-benzene
  参考文献：
  名称：

  摘要：

  Synthesis and characterisation of organochalcogens has demonstrated a high correlation between their electrochemical oxidation potential on the glassy carbon electrode, their activity in bioassays and an unprecedented antioxidant activity in neuronal cell culture (EC50 similar to 20 nM) making electrochemical methodology a valuable tool in drug design for Alzheimer's and related diseases.

  DOI：

  10.1039/b107972g
• 作为产物：
  描述：

  bis(4-methoxyphenyl)ditelluride 在 sodium tetrahydroborate 作用下， 生成 4-Methoxy-benzenetellurol
  参考文献：
  名称：

  摘要：

  Synthesis and characterisation of organochalcogens has demonstrated a high correlation between their electrochemical oxidation potential on the glassy carbon electrode, their activity in bioassays and an unprecedented antioxidant activity in neuronal cell culture (EC50 similar to 20 nM) making electrochemical methodology a valuable tool in drug design for Alzheimer's and related diseases.

  DOI：

  10.1039/b107972g

文献信息

• ——
  作者：Gregory I. Giles、Karen M. Tasker、Russell J. K. Johnson、Claus Jacob、Chris Peers、Kim N. Green

  DOI：10.1039/b107972g

  日期：2001.11.22

  Synthesis and characterisation of organochalcogens has demonstrated a high correlation between their electrochemical oxidation potential on the glassy carbon electrode, their activity in bioassays and an unprecedented antioxidant activity in neuronal cell culture (EC50 similar to 20 nM) making electrochemical methodology a valuable tool in drug design for Alzheimer's and related diseases.