glutaric acid bis-(2-dimethylamino-ethyl ester) | 67546-65-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: glutaric acid bis-(2-dimethylamino-ethyl ester)
• 英文别名: Glutarsaeure-bis-(2-dimethylamino-aethylester)；Bis-(2-dimethylaminoethyl) glutarate；bis[2-(dimethylamino)ethyl] pentanedioate
• CAS: 67546-65-0
• 化学式: C₁₃H₂₆N₂O₄
• 分子量: 274.36
• InChiKey: ZOJLDFAMFQUQLQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  19
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  59.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  glutaric acid bis-(2-dimethylamino-ethyl ester) 、 碘甲烷 在 丙酮 作用下， 生成 trimethylaminoethyl ester of glutaric acid diiodide
  参考文献：
  名称：

  SYNTHETIC CURARE SUBSTITUTES FROM ALIPHATIC DICARBOXYLIC ACID AMINOETHYL ESTERS

  摘要：

  DOI：

  10.1021/ja01177a535
• 作为产物：
  描述：

  Bis[2-(dimethylamino)ethyl] pentanedioate;dihydrochloride 、 potassium carbonate 以25%的产率得到
  参考文献：
  名称：

  MNDZHOYAN O. L.; GRIGORYAN N. A., AJKAKAN KIMIAKAN AMSAGIR, ARM. XIM. ZH., 1978, 31, HO 4, 250-253

  摘要：

  DOI：

文献信息

• Hair Growth Regulating Agent
  申请人：Suzuki Yasuto

  公开号：US20110130456A1

  公开（公告）日：2011-06-02

  A hair growth regulating agent containing, as an active ingredient, a compound represented by the following formula (I): [wherein R1 represents a substituted or unsubstituted, linear or branched C2 to C25 alkyl group; a group represented by the following formula (II): (wherein R1′ represents a substituted or unsubstituted, linear or branched C2 to C20 alkylene group, or —(CH2)n-O—(CH2)m}o-O—(CH2)p- in which each of n, m, o, and p is an integer from 1 to 6; X′ represents —CO—NH—, —O—CO—O—, —NH—CO—, —CO—O—, —O—CO—, or —O—; Y′ represents a substituted or unsubstituted C1 to C4 alkylene group; R2′ represents a hydrogen atom or a C1 to C4 alkyl group; R3′ represents a C1 to C4 alkyl group; and when R2′ and R3′ each represent a C1 to C4 alkyl group, the two alkyl groups may be identical to or different from each other); or a group represented by the following formula (III): (wherein R1′, X′, and Y′ have the same meanings as defined above; R4′, R5′, and R6′, which may be identical to or different from one another, each represent a C1 to C4 alkyl group; and A′- represents a counter ion); X represents —CO—NH—, —O—CO—O—, —NH—CO—, —CO—O—, —O—CO—, or —O—; Y represents a substituted or unsubstituted C1 to C4 alkylene group; R2 represents a hydrogen atom or a C1 to C4 alkyl group; R3 represents a C1 to C4 alkyl group; and when R2 and R3 each represent a C1 to C4 alkyl group, the two alkyl groups may be identical to or different from each other] or a salt of the compound; and/or a quaternary ammonium salt represented by the following formula (IV): (wherein R1, X, and Y have the same meanings as defined above; R4, R5, and R6, which may be identical to or different from one another, each represent a C1 to C4 alkyl group; and A- represents a counter ion).

  一种含有以下式（I）所代表的化合物作为活性成分的头发生长调节剂：[其中R1代表取代或未取代的直链或支链C2至C25烷基团；由以下式（II）表示的基团：（其中R1'代表取代或未取代的直链或支链C2至C20烷基烯基团，或者—（CH2）n-O—（CH2）m}o-O—（CH2）p-，其中n，m，o和p中的每个都是1至6的整数；X'代表—CO—NH—，—O—CO—O—，—NH—CO—，—CO—O—，—O—CO—或—O—；Y'代表取代或未取代的C1至C4烷基烯基团；R2'代表氢原子或C1至C4烷基团；R3'代表C1至C4烷基团；当R2'和R3'各自代表C1至C4烷基团时，这两个烷基团可以相同或不同）；或由以下式（III）表示的基团：（其中R1'，X'和Y'的含义与上述定义相同；R4'，R5'和R6'，可以相同也可以不同，各代表C1至C4烷基团；A'-代表一个对离子）；X代表—CO—NH—，—O—CO—O—，—NH—CO—，—CO—O—，—O—CO—或—O—；Y代表取代或未取代的C1至C4烷基烯基团；R2代表氢原子或C1至C4烷基团；R3代表C1至C4烷基团；当R2和R3各自代表C1至C4烷基团时，这两个烷基团可以相同或不同]或该化合物的盐；和/或由以下式（IV）所代表的季铵盐：（其中R1，X和Y的含义与上述定义相同；R4，R5和R6，可以相同也可以不同，各代表C1至C4烷基团；A-代表一个对离子）。
• Effect of Molecular Weight on the Ion Transport Mechanism in Polymerized Ionic Liquids
  作者：Fei Fan、Weiyu Wang、Adam P. Holt、Hongbo Feng、David Uhrig、Xinyi Lu、Tao Hong、Yangyang Wang、Nam-Goo Kang、Jimmy Mays、Alexei P. Sokolov

  DOI：10.1021/acs.macromol.6b00714

  日期：2016.6.28

  seven PolyILs were synthesized having degrees of polymerization ranging from 1 to 333, corresponding to molecular weights (MW) from 482 to 160 400 g/mol. Depolarized dynamic light scattering, broadband dielectric spectroscopy, rheology, and differential scanning calorimetry were employed to systematically study the influence of MW on the mechanism of ionic transport and segmental dynamics in these materials

  离子液体（ILs）的独特性能使其成为电化学应用的有希望的候选者。相应IL的聚合产生了一类称为聚合离子液体（PolyIL）的新型材料。尽管PolyIL提供了将IL的高电导率和聚合物的高机械强度相结合的可能性，但它们的电导率通​​常远低于相应的小分子IL的电导率。在本工作中，合成了七个聚合度为1至333的PolyIL，对应的分子量（MW）为482至160 400 g / mol。去极化动态光散射，宽带介电谱，流变学，差示扫描量热法和差示扫描量热法被用来系统地研究MW对这些材料中离子迁移和分段动力学的影响。修改后的Walden图分析显示，随着MW的增加，离子电导率从与结构弛豫紧密耦合转变为与离子强分离。
• Fusco et al., Gazzetta Chimica Italiana, 1949, vol. 79, p. 130
  作者：Fusco et al.

  DOI：——

  日期：——
• Immunochemical modeling of receptor-ligand reactions. Report II. Reaction of antibodies simulating N-choline receptor recognition with dicholine and dihomocholine dicarboxylic acid esters
  作者：A. A. Burkin、V. G. Zoryan、Yu. L. Kruglyak、L. N. Shitov、M. Z. Levkina

  DOI：10.1007/bf00773164

  日期：1992.4
• US8440717B2
  申请人：——

  公开号：US8440717B2

  公开（公告）日：2013-05-14