3-hydroxypropyl 3-phenylpropanoate | 107728-80-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-hydroxypropyl 3-phenylpropanoate
• CAS: 107728-80-3
• 化学式: C₁₂H₁₆O₃
• 分子量: 208.257
• InChiKey: HKCSRRTWQZVZME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-苯乙基-1,3-二恶烷 在 吡啶 、 N-羟基邻苯二甲酰亚胺 、 sodium perchlorate 作用下， 以 乙腈 为溶剂， 以9%的产率得到3-hydroxypropyl 3-phenylpropanoate
  参考文献：
  名称：

  Masui, Masaichiro; Kawaguchi, Tetsuo; Yoshida, Sumiko, Chemical and pharmaceutical bulletin, 1986, vol. 34, # 4, p. 1837 - 1839

  摘要：

  DOI：

文献信息

• Improved Method for the Diimide Reduction of Multiple Bonds on Solid-Supported Substrates
  作者：Keith R. Buszek、Neil Brown

  DOI：10.1021/jo0622173

  日期：2007.4.1

  A mild and improved method for reducing multiple bonds on various resins with diimide is described. The simple procedure readily generates diimide from 2-nitrobenzenesulfonohydrazide and triethylamine at room temperature. A number of representative multiple bonds in various steric and electronic environments were examined, including polar double bonds such as carbonyl and azo, for ease and selectivity of reduction. A general trend of reactivity was identified which revealed, inter alia, that terminal olefins, 1,2-disubstituted olefins, electron-poor olefins, and terminal alkynes were the most easily reduced.
• Masui, Masaichiro; Kawaguchi, Tetsuo; Yoshida, Sumiko, Chemical and pharmaceutical bulletin, 1986, vol. 34, # 4, p. 1837 - 1839
  作者：Masui, Masaichiro、Kawaguchi, Tetsuo、Yoshida, Sumiko、Ozaki, Shigeko

  DOI：——

  日期：——
• MASUI, MASAICHIRO;KAWAGUCHI, TETSUO;YOSHIDA, SUMIKO;OZAKI, SHIGEKO, CHEM. AND PHARM. BULL., 1986, 34, N 4, 1837-1839
  作者：MASUI, MASAICHIRO、KAWAGUCHI, TETSUO、YOSHIDA, SUMIKO、OZAKI, SHIGEKO

  DOI：——

  日期：——
• Direct Conversion of Aromatic 1,3-Dioxanes to Hydroxypropyl Esters with Pyridinium Hydrobromide Perbromide and Sodium Acetate in Water
  作者：Shinsei Sayama

  DOI：10.3987/com-17-13682

  日期：——

  Various aromatic 1,3-dioxanes were directly converted to respective hydorxypropyl esters with pyridinum hydrobromide perbromide and sodium acetate in water at room temperature.