trans 2,6-dimethoxy cinnamyl alcohol | 126985-99-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trans 2,6-dimethoxy cinnamyl alcohol
• 英文别名: 3-(2,6-Dimethoxyphenyl)prop-2-en-1-ol；(E)-3-(2,6-dimethoxyphenyl)prop-2-en-1-ol
• CAS: 126985-99-7
• 化学式: C₁₁H₁₄O₃
• 分子量: 194.23
• InChiKey: BPXCEKOKVSXJQZ-SNAWJCMRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  trans 2,6-dimethoxy cinnamyl alcohol 在 吡啶 、 chromium(VI) oxide 作用下， 以 二氯甲烷 为溶剂， 反应 20.0h， 以40%的产率得到(E)-2,6-dimethoxycinnamaldehyde
  参考文献：
  名称：

  Occurrence of 2,6-Dimethoxy cinnamaldehyde in taxus floridana and structural revision of taxiflorine to taxchinin M

  摘要：

  Taxiflorine, originally isolated from the needles of Taxus floridana and described previously, has its structure revised to that of taxchinin M. Four other known taxanes also isolated were: I-deoxy baccatin IV, 1-hydroxy baccatin 1, 10-deacetyl paclitaxel-7-xyloside and 13-deacetyl taxiflorine (taxchinin L), together with: trans-2,6-dimethoxy cinnamaldehyde, rhododendrol, ponasterone A and alpha-conidendrin. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(98)00089-2
• 作为产物：
  描述：

  2,6-二甲氧基苯甲醛 在 哌啶 、 吡啶 、 lithium aluminium tetrahydride 、 potassium carbonate 作用下， 以 四氢呋喃 、 丙酮 为溶剂， 反应 20.0h， 生成 trans 2,6-dimethoxy cinnamyl alcohol
  参考文献：
  名称：

  Occurrence of 2,6-Dimethoxy cinnamaldehyde in taxus floridana and structural revision of taxiflorine to taxchinin M

  摘要：

  Taxiflorine, originally isolated from the needles of Taxus floridana and described previously, has its structure revised to that of taxchinin M. Four other known taxanes also isolated were: I-deoxy baccatin IV, 1-hydroxy baccatin 1, 10-deacetyl paclitaxel-7-xyloside and 13-deacetyl taxiflorine (taxchinin L), together with: trans-2,6-dimethoxy cinnamaldehyde, rhododendrol, ponasterone A and alpha-conidendrin. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(98)00089-2

文献信息

• Occurrence of 2,6-Dimethoxy cinnamaldehyde in taxus floridana and structural revision of taxiflorine to taxchinin M
  作者：Koppaka V Rao、James H Johnson

  DOI：10.1016/s0031-9422(98)00089-2

  日期：1998.11

  Taxiflorine, originally isolated from the needles of Taxus floridana and described previously, has its structure revised to that of taxchinin M. Four other known taxanes also isolated were: I-deoxy baccatin IV, 1-hydroxy baccatin 1, 10-deacetyl paclitaxel-7-xyloside and 13-deacetyl taxiflorine (taxchinin L), together with: trans-2,6-dimethoxy cinnamaldehyde, rhododendrol, ponasterone A and alpha-conidendrin. (C) 1998 Elsevier Science Ltd. All rights reserved.