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    热门化合物HOT
    • 喹啉
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    —— Ethyl 5-{[(4-ethoxyphenyl)sulfonyl]amino}-2-propyl-1-benzofuran-3-carboxylate —— C22H25NO6S
    Ethyl 5-{[(4-ethoxyphenyl)sulfonyl]amino}-2-propyl-1-benzofuran-3-carboxylate
    —— ethyl (2Z,5R)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-2-[(2-methyl-1H-indol-3-yl)methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C29H29N3O5S
    ethyl (2Z,5R)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-2-[(2-methyl-1H-indol-3-yl)methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— Ethyl 5-{acetyl[(4-fluoro-2-methylphenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylate —— C21H20FNO6S
    Ethyl 5-{acetyl[(4-fluoro-2-methylphenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylate
    —— ethyl (2Z,5S)-2-[(5-bromo-2-methoxyphenyl)methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C27H27BrN2O6S
    ethyl (2Z,5S)-2-[(5-bromo-2-methoxyphenyl)methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2Z,5S)-2-[[4-(dimethylamino)phenyl]methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C28H31N3O5S
    ethyl (2Z,5S)-2-[[4-(dimethylamino)phenyl]methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2E,5S)-2-[(2-chlorophenyl)methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C26H25ClN2O5S
    ethyl (2E,5S)-2-[(2-chlorophenyl)methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2Z,5S)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-2-[(4-prop-2-enoxyphenyl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C29H30N2O6S
    ethyl (2Z,5S)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-2-[(4-prop-2-enoxyphenyl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2E,5S)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-2-[(2-prop-2-enoxyphenyl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C29H30N2O6S
    ethyl (2E,5S)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-2-[(2-prop-2-enoxyphenyl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2Z,5R)-5-(3-ethoxy-4-methoxyphenyl)-2-[(3-methoxy-4-methylphenyl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C28H30N2O6S
    ethyl (2Z,5R)-5-(3-ethoxy-4-methoxyphenyl)-2-[(3-methoxy-4-methylphenyl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2Z,5R)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-2-[(5-piperidin-1-ylfuran-2-yl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C29H33N3O6S
    ethyl (2Z,5R)-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-2-[(5-piperidin-1-ylfuran-2-yl)methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2E,5R)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-5-(2-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C27H27BrN2O6S
    ethyl (2E,5R)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-5-(2-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— Ethyl 5-[(2-naphthylsulfonyl)amino]-2-propylnaphtho[1,2-b]furan-3-carboxylate —— C28H25NO5S
    Ethyl 5-[(2-naphthylsulfonyl)amino]-2-propylnaphtho[1,2-b]furan-3-carboxylate
    —— ethyl (2E,5S)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-5-(2-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C27H27BrN2O6S
    ethyl (2E,5S)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-5-(2-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2Z,5R)-2-[(5-bromo-2-methoxyphenyl)methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C27H27BrN2O6S
    ethyl (2Z,5R)-2-[(5-bromo-2-methoxyphenyl)methylidene]-5-(3-ethoxy-4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2E,5R)-5-(2,4-dimethoxyphenyl)-2-[(4-hydroxy-3-methoxy-5-prop-2-enylphenyl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C29H30N2O7S
    ethyl (2E,5R)-5-(2,4-dimethoxyphenyl)-2-[(4-hydroxy-3-methoxy-5-prop-2-enylphenyl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2E,5S)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-7-methyl-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C26H25BrN2O5S
    ethyl (2E,5S)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-7-methyl-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2Z,5R)-5-(1,3-benzodioxol-5-yl)-2-[(2-bromo-5-methoxyphenyl)methylidene]-3-oxo-7-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C30H23BrN2O6S
    ethyl (2Z,5R)-5-(1,3-benzodioxol-5-yl)-2-[(2-bromo-5-methoxyphenyl)methylidene]-3-oxo-7-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (2Z,5S)-5-(1,3-benzodioxol-5-yl)-2-[(5-bromo-2-hydroxy-3-methoxyphenyl)methylidene]-3-oxo-7-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C30H23BrN2O7S
    ethyl (2Z,5S)-5-(1,3-benzodioxol-5-yl)-2-[(5-bromo-2-hydroxy-3-methoxyphenyl)methylidene]-3-oxo-7-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (5S,7E)-7-(1,3-benzodioxol-5-ylmethylidene)-4-(3-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C28H23N3O5S2
    ethyl (5S,7E)-7-(1,3-benzodioxol-5-ylmethylidene)-4-(3-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— ethyl (5R,7E)-4-(4-methylphenyl)-8-oxo-9-phenyl-7-(thiophen-2-ylmethylidene)-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C25H21N3O3S3
    ethyl (5R,7E)-4-(4-methylphenyl)-8-oxo-9-phenyl-7-(thiophen-2-ylmethylidene)-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— ethyl (2E,5S)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-5-(3-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C27H27BrN2O6S
    ethyl (2E,5S)-2-[(2-bromo-5-ethoxy-4-methoxyphenyl)methylidene]-5-(3-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl (5S,7E)-7-(1,3-benzodioxol-5-ylmethylidene)-4-(4-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C28H23N3O5S2
    ethyl (5S,7E)-7-(1,3-benzodioxol-5-ylmethylidene)-4-(4-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— ethyl (5S,7Z)-7-[(4-methoxyphenyl)methylidene]-8-oxo-4,9-diphenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C27H23N3O4S2
    ethyl (5S,7Z)-7-[(4-methoxyphenyl)methylidene]-8-oxo-4,9-diphenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— ethyl (5S)-4-(4-chlorophenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C19H16ClN3O3S2
    ethyl (5S)-4-(4-chlorophenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— ethyl 4-({(2Z,5E)-5-[(1,2-dimethyl-1H-indol-3-yl)methylidene]-3-methyl-4-oxo-1,3-thiazolidin-2-ylidene}amino)benzoate —— C24H23N3O3S
    ethyl 4-({(2Z,5E)-5-[(1,2-dimethyl-1H-indol-3-yl)methylidene]-3-methyl-4-oxo-1,3-thiazolidin-2-ylidene}amino)benzoate
    —— ethyl (5S,7Z)-7-[(4-methylphenyl)methylidene]-8-oxo-4,9-diphenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C27H23N3O3S2
    ethyl (5S,7Z)-7-[(4-methylphenyl)methylidene]-8-oxo-4,9-diphenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— ethyl (2Z,5S)-5-(4-fluorophenyl)-7-methyl-2-[[5-(4-methyl-3-nitrophenyl)furan-2-yl]methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C28H22FN3O6S
    ethyl (2Z,5S)-5-(4-fluorophenyl)-7-methyl-2-[[5-(4-methyl-3-nitrophenyl)furan-2-yl]methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl [2-({5-oxo-3-phenyl-1-[3-(trifluoromethyl)phenyl]-1,5-dihydro-4H-pyrazol-4-ylidene}methyl)phenoxy]acetate —— C27H21F3N2O4
    ethyl [2-({5-oxo-3-phenyl-1-[3-(trifluoromethyl)phenyl]-1,5-dihydro-4H-pyrazol-4-ylidene}methyl)phenoxy]acetate
    —— ethyl (5R,7Z)-7-benzylidene-4-(4-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C27H23N3O3S2
    ethyl (5R,7Z)-7-benzylidene-4-(4-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— ethyl (2Z,5S)-5-(1,3-benzodioxol-5-yl)-2-[(2-bromo-5-methoxyphenyl)methylidene]-3-oxo-7-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C30H23BrN2O6S
    ethyl (2Z,5S)-5-(1,3-benzodioxol-5-yl)-2-[(2-bromo-5-methoxyphenyl)methylidene]-3-oxo-7-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl 3-[5-[(E)-[(11S)-11-(2,5-dimethoxyphenyl)-13-oxo-15-thia-12,17-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,16-pentaen-14-ylidene]methyl]furan-2-yl]benzoate —— C36H30N2O6S
    ethyl 3-[5-[(E)-[(11S)-11-(2,5-dimethoxyphenyl)-13-oxo-15-thia-12,17-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,16-pentaen-14-ylidene]methyl]furan-2-yl]benzoate
    —— ethyl (2Z,5R)-5-(4-fluorophenyl)-7-methyl-2-[[5-(4-methyl-3-nitrophenyl)furan-2-yl]methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C28H22FN3O6S
    ethyl (2Z,5R)-5-(4-fluorophenyl)-7-methyl-2-[[5-(4-methyl-3-nitrophenyl)furan-2-yl]methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl 4-[[5-[(2Z)-2-[(4-formylphenyl)methylidene]hydrazinyl]-[1,2,5]oxadiazolo[3,4-b]pyrazin-6-yl]amino]benzoate —— C21H17N7O4
    ethyl 4-[[5-[(2Z)-2-[(4-formylphenyl)methylidene]hydrazinyl]-[1,2,5]oxadiazolo[3,4-b]pyrazin-6-yl]amino]benzoate
    —— ethyl 2-[7-[(2R)-2-hydroxy-3-(4-methoxyphenoxy)propyl]-3-methyl-2,6-dioxopurin-8-yl]sulfanylacetate —— C20H24N4O7S
    ethyl 2-[7-[(2R)-2-hydroxy-3-(4-methoxyphenoxy)propyl]-3-methyl-2,6-dioxopurin-8-yl]sulfanylacetate
    —— Ethyl 2-[2-bromo-6-methoxy-4-[[(2-morpholin-4-ium-4-ylacetyl)hydrazinylidene]methyl]phenoxy]acetate —— C18H25BrN3O6+
    Ethyl 2-[2-bromo-6-methoxy-4-[[(2-morpholin-4-ium-4-ylacetyl)hydrazinylidene]methyl]phenoxy]acetate
    —— ethyl (5S,7Z)-7-benzylidene-4-(4-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate —— C27H23N3O3S2
    ethyl (5S,7Z)-7-benzylidene-4-(4-methylphenyl)-8-oxo-9-phenyl-1,6-dithia-3,4,9-triazaspiro[4.4]non-2-ene-2-carboxylate
    —— (E)-4-oxo-4-[2-[[2-(trifluoromethyl)phenyl]carbamoyl]anilino]but-2-enoic acid —— C18H13F3N2O4
    (E)-4-oxo-4-[2-[[2-(trifluoromethyl)phenyl]carbamoyl]anilino]but-2-enoic acid
    —— ethyl (4S)-4-(4-bromothiophen-2-yl)-2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydroquinoline-3-carboxylate —— C19H22BrNO3S
    ethyl (4S)-4-(4-bromothiophen-2-yl)-2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydroquinoline-3-carboxylate
    —— ethyl (2R,3R,7S,13R,17S)-2-(3-nitrophenyl)-1-azapentacyclo[10.6.1.03,7.08,19.013,17]nonadeca-5,8,10,12(19),14-pentaene-10-carboxylate —— C27H26N2O4
    ethyl (2R,3R,7S,13R,17S)-2-(3-nitrophenyl)-1-azapentacyclo[10.6.1.03,7.08,19.013,17]nonadeca-5,8,10,12(19),14-pentaene-10-carboxylate
    —— ethyl (2E,5S)-7-methyl-3-oxo-5-phenyl-2-[(Z)-3-phenylprop-2-enylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C25H22N2O3S
    ethyl (2E,5S)-7-methyl-3-oxo-5-phenyl-2-[(Z)-3-phenylprop-2-enylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
    —— ethyl 2-[(5S)-4-[hydroxy-(3-methyl-4-prop-2-enoxyphenyl)methylidene]-2,3-dioxo-5-(4-propan-2-ylphenyl)pyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate —— C31H32N2O6S
    ethyl 2-[(5S)-4-[hydroxy-(3-methyl-4-prop-2-enoxyphenyl)methylidene]-2,3-dioxo-5-(4-propan-2-ylphenyl)pyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
    —— ethyl 2-[(5S)-4-[hydroxy-(4-methoxy-3-methylphenyl)methylidene]-2,3-dioxo-5-(3,4,5-trimethoxyphenyl)pyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate —— C29H30N2O9S
    ethyl 2-[(5S)-4-[hydroxy-(4-methoxy-3-methylphenyl)methylidene]-2,3-dioxo-5-(3,4,5-trimethoxyphenyl)pyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
    —— ethyl (4R)-6-methyl-4-[3-(3-methyl-4-prop-2-enoxyphenyl)-1-phenylpyrazol-4-yl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C27H28N4O4
    ethyl (4R)-6-methyl-4-[3-(3-methyl-4-prop-2-enoxyphenyl)-1-phenylpyrazol-4-yl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— Ethyl 4-(3,4-dimethoxyphenyl)-2-[3-(4-ethylpiperazin-1-yl)propanoylamino]thiophene-3-carboxylate —— C24H33N3O5S
    Ethyl 4-(3,4-dimethoxyphenyl)-2-[3-(4-ethylpiperazin-1-yl)propanoylamino]thiophene-3-carboxylate
    —— Ethyl 4-(4-chlorophenyl)-5-methyl-2-[[2-(4-methylpiperidin-1-ium-1-yl)acetyl]amino]thiophene-3-carboxylate —— C22H28ClN2O3S+
    Ethyl 4-(4-chlorophenyl)-5-methyl-2-[[2-(4-methylpiperidin-1-ium-1-yl)acetyl]amino]thiophene-3-carboxylate
    —— ethyl 4-[(3S)-3-[4-(3-methoxyphenyl)piperazin-1-yl]-2,5-dioxopyrrolidin-1-yl]benzoate —— C24H27N3O5
    ethyl 4-[(3S)-3-[4-(3-methoxyphenyl)piperazin-1-yl]-2,5-dioxopyrrolidin-1-yl]benzoate
    —— ethyl (6R)-2-[[5-[[(6R)-3-ethoxycarbonyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]amino]-5-oxopentanoyl]amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate —— C29H38N2O6S2
    ethyl (6R)-2-[[5-[[(6R)-3-ethoxycarbonyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]amino]-5-oxopentanoyl]amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
    —— ethyl 4-[(3R)-3-[4-(3-methoxyphenyl)piperazin-1-yl]-2,5-dioxopyrrolidin-1-yl]benzoate —— C24H27N3O5
    ethyl 4-[(3R)-3-[4-(3-methoxyphenyl)piperazin-1-yl]-2,5-dioxopyrrolidin-1-yl]benzoate
    —— ethyl 4-[(3R)-3-[4-(4-methoxyphenyl)piperazin-1-ium-1-yl]-2,5-dioxopyrrolidin-1-yl]benzoate —— C24H28N3O5+
    ethyl 4-[(3R)-3-[4-(4-methoxyphenyl)piperazin-1-ium-1-yl]-2,5-dioxopyrrolidin-1-yl]benzoate
    —— ethyl (2E,5R)-2-[[4-methoxy-3-[(2,4,6-trichlorophenoxy)methyl]phenyl]methylidene]-7-methyl-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate —— C31H25Cl3N2O5S
    ethyl (2E,5R)-2-[[4-methoxy-3-[(2,4,6-trichlorophenoxy)methyl]phenyl]methylidene]-7-methyl-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate