(1S,2R)-1-Bromomethyl-2-(2-bromo-pentyl)-cyclohexane | 137303-33-4

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机溴化物
• 英文名称: (1S,2R)-1-Bromomethyl-2-(2-bromo-pentyl)-cyclohexane
• CAS: 137303-33-4
• 化学式: C₁₂H₂₂Br₂
• 分子量: 326.115
• InChiKey: YNTDNAFFNCTDDQ-XFKKCKKNSA-N

反应信息

• 作为反应物：
  描述：

  (1S,2R)-1-Bromomethyl-2-(2-bromo-pentyl)-cyclohexane 在 potassium sulfide 作用下， 以 乙醇 为溶剂， 生成 (3R,4aR,8aS)-3-Propyl-octahydro-isothiochromene 、 (1S,3aR,7aR)-1-Butyl-octahydro-benzo[c]thiophene
  参考文献：
  名称：

  Synthesis of 1-substituted trans-2-thiahydrindanes and 3-substituted trans-2-thiadecalins

  摘要：

  Methods of synthesis of 1-R-trans-2-thiahydrindanes and 3-R-trans-2-thiadecalins from trans-1-methoxymethyl-2-chlorocyclohexane have been developed. The order of the chromatographic elution of the isomeric sulfides formed has been found. The configurations of the compounds have been established by H-1 and C-13 NMR spectroscopy. The characteristics of the intermediate and final compounds are given. The splitting of 1-R-trans-2-oxahydrindanes and 3-R-trans-2-oxadecalins by the PBr3/conc. HBr system has been effected.

  DOI：

  10.1007/bf01172271
• 作为产物：
  描述：

  (4aR,8aS)-3-Propyl-octahydro-isochromene 在 氢溴酸 、 三溴化磷 作用下， 生成 (1S,2R)-1-Bromomethyl-2-(2-bromo-pentyl)-cyclohexane
  参考文献：
  名称：

  Synthesis of 1-substituted trans-2-thiahydrindanes and 3-substituted trans-2-thiadecalins

  摘要：

  Methods of synthesis of 1-R-trans-2-thiahydrindanes and 3-R-trans-2-thiadecalins from trans-1-methoxymethyl-2-chlorocyclohexane have been developed. The order of the chromatographic elution of the isomeric sulfides formed has been found. The configurations of the compounds have been established by H-1 and C-13 NMR spectroscopy. The characteristics of the intermediate and final compounds are given. The splitting of 1-R-trans-2-oxahydrindanes and 3-R-trans-2-oxadecalins by the PBr3/conc. HBr system has been effected.

  DOI：

  10.1007/bf01172271