| 488791-23-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 488791-23-7
• 化学式: C₃₇H₃₈F₆O₆
• 分子量: 692.696
• InChiKey: OGAFUJHJBRJFEL-CYWVLGPGSA-N

反应信息

• 作为产物：
  描述：

  (3SR,8S)-falcarindiol 、 (R)-methoxytrifluoromethylphenylacetyl chloride 在 4-二甲氨基吡啶 、 氘代吡啶 作用下， 反应 3.0h， 生成 、 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (Z)-(S)-1-[(S)-5-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxy)-hept-6-ene-1,3-diynyl]-dec-2-enyl ester
  参考文献：
  名称：

  Oploxynes A and B, Polyacetylenes from the Stems of Oplopanax elatus

  摘要：

  Two new polyacetylenes, oploxynes A (1) and B (2), and the known oplopandiol (3) and falcarindiol (4) were isolated from the stein of Oplopanax clams. The structures of compounds 1 and 2 were determined to be 9,10-epoxyheptadeca-4,6-diyne-3,8-diol and 10-methoxyheptadeca-4,6-diyne-3,8,9-triol, respectively, on the basis of their UV, MS, and NMR data. The absolute configurations of these compounds were determined using the modified Mosher's method and acetonide formation. Oploxyne A (1), oplopandiol (3), and falcarindiol (4) inhibited the formation of nitric oxide (NO) and prostaglandin E(2) (PGE(2)) in lipopolysaccharide (LPS)-induced murine macrophage RAW 267.7 cells.

  DOI：

  10.1021/np900628j