| 1192159-51-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• CAS: 1192159-51-5
• 化学式: C₁₈H₁₅NO
• 分子量: 261.323
• InChiKey: VXQUEGZOUFHFHQ-INIZCTEOSA-N

反应信息

• 作为反应物：
  描述：

  在 1% Pd/C 、 氢气 作用下， 以 乙醇 为溶剂， 反应 24.0h， 以69%的产率得到
  参考文献：
  名称：

  An Enantioselective Approach to Synthesis of Advanced Chiral Templates for the Construction of Indolic and Indolizidinic Alkaloids

  摘要：

  A new approach for the syntheses of chiral indolic and indolizidinic templates is presented. They were obtained in three steps starting from a chiral primary amino-vinylsilane. The key step was the N-acyliminium pi-cyclization, leading diastereoselectively to the formation of the six membered ring templates.

  DOI：

  10.3987/com-09-11690
• 作为产物：
  描述：

  (4S,10bS)-4-phenyl-4,10b-dihydro-3H-pyrido[1,2-b]isoindol-6-one 在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 0.5h， 以84%的产率得到
  参考文献：
  名称：

  An Enantioselective Approach to Synthesis of Advanced Chiral Templates for the Construction of Indolic and Indolizidinic Alkaloids

  摘要：

  A new approach for the syntheses of chiral indolic and indolizidinic templates is presented. They were obtained in three steps starting from a chiral primary amino-vinylsilane. The key step was the N-acyliminium pi-cyclization, leading diastereoselectively to the formation of the six membered ring templates.

  DOI：

  10.3987/com-09-11690