5-nitro-N-phenyl-2-(phenylethynyl)benzamide | 1202400-98-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-nitro-N-phenyl-2-(phenylethynyl)benzamide
• CAS: 1202400-98-3
• 化学式: C₂₁H₁₄N₂O₃
• 分子量: 342.354
• InChiKey: YYHJUBDHEQNTIR-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  5-nitro-N-phenyl-2-(phenylethynyl)benzamide 在 silver trifluoromethanesulfonate 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 3.0h， 以91%的产率得到(Z)-N-(7-nitro-3-phenyl-1H-isochromen-1-ylidene)aniline
  参考文献：
  名称：

  Highly Efficient Access to Iminoisocoumarins and α-Iminopyrones via AgOTf-Catalyzed Intramolecular Enyne−Amide Cyclization

  摘要：

  Iminoisocoumarins and alpha-iminopyrones are prepared via Sonogashira coupling and AgOTf-catalyzed 6-endo-dig O-cyclization of the enyne-amide system in dichloroethane, in one pot or stepwise, respectively.

  DOI：

  10.1021/jo9023478
• 作为产物：
  描述：

  2-iodo-5-nitro-N-phenylbenzamide 、 苯乙炔 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 三乙胺 作用下， 以 1,2-二氯乙烷 为溶剂， 生成 5-nitro-N-phenyl-2-(phenylethynyl)benzamide
  参考文献：
  名称：

  Highly Efficient Access to Iminoisocoumarins and α-Iminopyrones via AgOTf-Catalyzed Intramolecular Enyne−Amide Cyclization

  摘要：

  Iminoisocoumarins and alpha-iminopyrones are prepared via Sonogashira coupling and AgOTf-catalyzed 6-endo-dig O-cyclization of the enyne-amide system in dichloroethane, in one pot or stepwise, respectively.

  DOI：

  10.1021/jo9023478

文献信息

• Facile synthesis of 11-aryl-6H-isoindolo[2,1-a]indol-6-ones via hypervalent iodine(<scp>iii</scp>)-promoted cascade cyclization
  作者：Kapil Dev、Rakesh Maurya

  DOI：10.1039/c4ra10452h

  日期：——

  An efficient method was developed for the synthesis of a tetracyclic fused indole and isoindoline ring system, under metal-free conditions. The hypervalent iodine PIDA-mediated regioselective as well as chemoselective intramolecular cascade oxidative cyclization of 2-(1-arylethynyl)benzamides afforded 11-aryl-6H-isoindolo[2,1-a]indol-6-ones at room temperature in good to excellent yields.

  开发了一种在无金属条件下合成四环稠合吲哚和异吲哚啉环系的有效方法。2-（1-芳基乙炔基）苯甲酰胺的高价碘PIDA介导的区域选择性以及化学选择性的分子内级联氧化环化在室温下提供了11-芳基-6 H-异吲哚并[2,1 - a ]吲哚-6-酮。达到优异的产量。