| 1352788-30-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 芳基卤化物
• CAS: 1352788-30-7
• 化学式: C₁₀H₇Cl₃O₂S
• 分子量: 297.589
• InChiKey: KMNIFVCQZIPPLT-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  (3Z)-4-[(2-hydroxyethyl)amino]pent-3-en-2-one 、 以 乙醇 为溶剂， 以45.5%的产率得到3-(3,4,5-trichlorothien-2-yl)-5-(2-hydroxyethyl)-amino-2,4-diacetyl-1-methyl-4-cyclohexen-1-ol
  参考文献：
  名称：

  Synthesis of substituted 5-N-(R)amino-4-cyclohexyl-1-ols by the reaction of secondary enaminones of β-dicarbonyl compounds with chalcones

  摘要：

  Reaction of secondary enaminones of acetylacetone or acetoacetic ester with chalcones at room temperature, is shown to lead to 5-N-(R)amino-4-cyclohexen-1-ols, distinctly to the reaction of the related primary derivatives leading to 1,4-dihydropyridines. Tertiary enaminones of identical structure are found not reacting with chalcones under the similar conditions. The reasons for the difference in the behavior of primary, secondary and tertiary enaminones in the reaction with chalcones are discussed.

  DOI：

  10.1134/s1070363211100203