二(2-噻吩基)碘鎓 | 45955-43-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 芳基卤化物
• 中文名称: 二(2-噻吩基)碘鎓
• 英文名称: Iodonium thiophene
• 英文别名: dithiophen-2-yliodanium
• CAS: 45955-43-9
• 化学式: C8H6IS2+
• 分子量: 293.2
• InChiKey: ZOQWONKTSYEVDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  56.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2934999090

文献信息

• [EN] IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF<br/>[FR] ANALOGUES D'IODONIUM EN TANT QU'INHIBITEURS DE NADPH OXYDASES ET D'AUTRES FLAVINES DÉSHYDROGÉNASES, LEURS FORMULATIONS ET LEURS UTILISATIONS
  申请人：US HEALTH

  公开号：WO2015157145A1

  公开（公告）日：2015-10-15

  Disclosed herein are novel iodonium analogs having anticancer and anti-inflammatory activity.

  本文披露了具有抗癌和抗炎活性的新型碘化物类似物。
• POLARIZED FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE
  申请人：NITTO DENKO CORPORATION

  公开号：US20150049380A1

  公开（公告）日：2015-02-19

  A polarizing film, comprising a polarizer; transparent protective films with a water-vapor permeability of 150 g/m2/24 hours or less provided on both sides of the polarizer; and adhesive layers each interposed between the polarizer and one of the transparent protective films, wherein the adhesive layers are formed by applying an active energy ray to an active energy ray-curable adhesive composition containing a radically polymerizable compound, and the transparent protective films are bonded to the polarizer with the adhesive layers.

  一种偏光膜，包括偏光器；透明保护膜，在偏光器的两侧提供，其水汽渗透率为每平方米每24小时150克或以下；以及粘合层，每个粘合层夹在偏光器和一个透明保护膜之间，其中粘合层是通过将活性能量射线应用于含有自由基聚合化合物的活性能量射线可固化粘合剂组成的，透明保护膜与偏光器通过粘合层粘合在一起。
• ANALGESICS
  申请人：ONO PHARMACEUTICAL CO., LTD.

  公开号：EP1199078A1

  公开（公告）日：2002-04-24

  The prevention and/or treatment of pain, hyperalgesia and allodynia according to claim 1 which comprise, as an active ingredient, a condensed piperidine compound represented by formula (I), a non-toxic salt thereof, wherein all the symbols have the same meanings as defined in the specification. The compound of formula (I) of the present invention has analgetic effect in lower doses.

  2.根据权利要求1所述的预防和/或治疗疼痛、痛觉减退和异动症的药物，其活性成分包括由式(I)代表的缩合哌啶化合物及其无毒盐，其中所有符号的含义与说明书中定义的相同。 本发明的式(I)化合物在较低剂量时具有镇痛作用。
• REMEDIES FOR SJOEGREN'S SYNDROME
  申请人：ONO PHARMACEUTICAL CO., LTD.

  公开号：EP1256353A1

  公开（公告）日：2002-11-13

  It was found that an inducible nitric oxygen synthase (i-NOS) inhibitor is effective for Sjögren's syndrome, and based on this knowledge, an agent for treating and/or preventing Sjögren's syndrome comprising the i-NOS inhibitor as an active ingredient has been completed. As the i-NOS inhibitor, for example, a condensed piperidine compound represented by formula (I), an acid addition salt thereof or a hydrate thereof is preferably used: wherein symbols in the formula are described in the description.

  研究发现，一种诱导型一氧化氮合酶（i-NOS）抑制剂对斯约格伦综合征有效，基于这一认识，完成了一种治疗和/或预防斯约格伦综合征的制剂，该制剂包含作为活性成分的i-NOS抑制剂。作为 i-NOS 抑制剂，例如，优选使用由式（I）代表的缩合哌啶化合物、其酸加成盐或其水合物： 其中式中的符号已在说明中描述。
• REMEDIES FOR ALLERGIC DISEASES
  申请人：ONO PHARMACEUTICAL CO., LTD.

  公开号：EP1426060A1

  公开（公告）日：2004-06-09

  The present invention relates to an agent for the treatment and/or prevention of allergy which comprises, as an active ingredient, an inducible nitrogen monoxide synthase inhibitor, preferably a condensed piperidine compound represented by formula (I), or an acid addition salt thereof or a hydrate thereof:    wherein symbols are as defined in the specification. A therapeutic agent for allergy of the present invention which comprises an inducible nitrogen monoxide synthase inhibitor as an active ingredient is effective at low doses in the treatment of allergy.

  本发明涉及一种治疗和/或预防过敏的制剂，其活性成分包括一种诱导型一氧化氮合酶抑制剂，最好是由式（I）代表的缩合哌啶化合物，或其酸加成盐或其水合物： 其中符号如说明书中所定义。 本发明的过敏症治疗剂包含一种诱导型一氧化氮合酶抑制剂作为活性成分，在低剂量治疗过敏症时有效。