p-decylphenylmagnesium bromide | 228263-67-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-decylphenylmagnesium bromide
• CAS: 228263-67-0
• 化学式: C₁₆H₂₅BrMg
• 分子量: 321.584
• InChiKey: XGELYHAKHCGHAG-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  5.01
• 重原子数：
  18.0
• 可旋转键数：
  10.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  p-decylphenylmagnesium bromide 、 足球烯 在 copper bromide dimethyl sulfide complex 、 氯化铵 作用下， 以 四氢呋喃 、 邻二氯苯 、 水 为溶剂， 反应 2.0h， 以99%的产率得到6,9,12,15,18-pentakis(4-decylphenyl)-1,6,9,12,15,18-hexahydro(C60-Ih)[5,6]fullerene
  参考文献：
  名称：

  Preparation and Properties of Vesicles Made of Nonpolar/Polar/Nonpolar Fullerene Amphiphiles

  摘要：

  Twenty potassium complexes of penta-[(4-substituted)phenyl][60]fullerene anions were synthesized and examined for their ability to form bilayer vesicles in water. The 4-substituents include alkyl groups ranging from methyl to icosanyl groups and perfluoromethyl, perfluorobutyl, and perfluorooctyl groups. The overall structure of the amphiphiles can be described as a nonpolar/polar/nonpolar (n-p-n') motif as opposed to the usual polar/nonpolar motif of lipid amphiphiles. Despite the hydrophobicity of the fullerene moiety (n-part) and alkyl/perfluoroalkyl chains (n'-part), all compounds except for the one with perfluoromethyl groups were soluble in water because of the centrally located fullerene cyclopentadienide (p-part) and spontaneously formed a vesicle of 25- to 60-nm diameter with a narrow unimodal size distribution. The vesicles are stable upon heating to 90 degrees C or standing over one year in air, as well as on a solid substrate in air or in vacuum, maintaining their spherical form. The vesicle membrane consists of an interdigitated bilayer of the amphiphile molecules, in which the fullerene n-part is inside and the n'-side is exposed to water. These vesicles, in particular the one bearing icosanyl chains, exhibit the smallest water permeability coefficient ever found for a self-assembled membrane in water.

  DOI：

  10.1021/ja200498g

文献信息

• Subnanomolar Precipitator of Thiophilic Metals
  申请人：Janda Kim D.

  公开号：US20080241943A1

  公开（公告）日：2008-10-02

  A fluorescent dye-doped crystalline assay is employed for selection and detection of thiophilic heavy metal ions. While comparable in analytical performance to known solution based methodologies, the formation of crystalline analytes provides for signal amplification, and consequently, a powerful platform whose analysis is directly amenable to high-throughput video capture systems. In a microcapillary format, this assay is capable of screening hundreds of samples per day for the presence of subnanomolar concentrations of Hg 2+ using a conventional fluorescence microscope.

  采用荧光染料掺杂结晶测定法选择和检测亲硫重金属离子。这种方法与已知的溶液基方法在分析性能上相当，但结晶分析物的形成提供了信号放大，因此，这是一个强大的平台，其分析可直接适用于高通量视频捕获系统。在微型毛细管格式下，该测定法能够使用传统荧光显微镜每天筛选数百个样品，以检测亚纳摩尔浓度的Hg2+的存在。
• [EN] SUBNANOMOLAR PRECIPITATOR OF THIOPHILIC METALS<br/>[FR] SELECTEUR SUBNANOMOLAIRE POUR METAUX THIOPHILES
  申请人：SCRIPPS RESEARCH INST

  公开号：WO2006055883A2

  公开（公告）日：2006-05-26

  [EN] A fluorescent dye-doped crystalline assay is employed for selection and detection of thiophilic heavy metal ions. While comparable in analytical performance to known solution based methodologies, the formation of crystalline analytes provides for signal amplification, and consequently, a powerful platform whose analysis is directly amenable to high-throughput video capture systems. In a microcapillary format, this assay is capable of screening hundreds of samples per day for the presence of subnanomolar concentrations of Hg²⁺ using a conventional fluorescence microscope.
  [FR] La présente invention concerne un essai sur cristaux utilisant un dopage à la teinture fluorescente pour sélectionner et détecter des ions de métaux thiophiles lourds. Tout en gardant une puissance d'analyse comparable à ce que donnent les procédés actuels à base de solution, le procédé de l'invention avec formation d'analysats cristallins permet en outre une amplification du signal. Il en découle qu'on peut ainsi disposer d'une puissante plate-forme dont l'analyse est exploitable pour des systèmes à capture vidéo à fort débit. En format microcapillaire, cet essai permet de rechercher systématiquement dans des centaines d'échantillons chaque jour la présence de concentrations subnanomolaire de Hg²⁺ avec un microscope conventionnel à fluorescence.