1-(1-Bromoethyl)-2,3,4,5,6-pentafluorobenzene | 652-28-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(1-Bromoethyl)-2,3,4,5,6-pentafluorobenzene
• CAS: 652-28-8
• 化学式: C₈H₄BrF₅
• 分子量: 275.01
• InChiKey: CNLDGKGDVGXTEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  二十二酸 、 1-(1-Bromoethyl)-2,3,4,5,6-pentafluorobenzene 以75%的产率得到
  参考文献：
  名称：

  HOFMANN, UTE;HOLZER, SABINE;MEESE, CLAUS O., J. CHROMATOGR., 508,(1990) N, C. 349-356

  摘要：

  DOI：
• 作为产物：
  描述：

  1-(五氟苯基)乙醇 、 三溴化磷 以65%的产率得到
  参考文献：
  名称：

  HOFMANN, UTE;HOLZER, SABINE;MEESE, CLAUS O., J. CHROMATOGR., 508,(1990) N, C. 349-356

  摘要：

  DOI：

文献信息

• Process for the production of living radical polymers and polymers
  申请人：Yamago Shigeru

  公开号：US20060135711A1

  公开（公告）日：2006-06-22

  A process for producing a living radical polymer characterized in that a vinyl monomer is polymerized with use of an organotellurium compound represented by the formula (1) and an azo type polymerization initiator, and the living radical polymer obtainable by the process wherein R 1 is C 1 -C 8 alkyl, aryl, substituted aryl or an aromatic heterocyclic group, R 2 and R 3 are each a hydrogen atom or C 1 -C 8 alkyl, and R 4 is aryl, substituted aryl, an aromatic heterocyclic group, acyl, oxycarbonyl or cyano.

  使用由公式（1）表示的有机碲化合物和偶氮类聚合引发剂聚合乙烯单体的生活自由基聚合物的生产方法，其中所述生活自由基聚合物可通过该方法获得 其中R1为C1-C8烷基，芳基，取代芳基或芳香杂环基，R2和R3分别为氢原子或C1-C8烷基，R4为芳基，取代芳基，芳香杂环基，酰基，氧羰基或氰基。
• [EN] NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS)<br/>[FR] MODULATEURS SELECTIFS DU RECEPTEUR D'ANDROGENE A BASE DE DERIVES BENZIMIDAZOLIQUES
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2006039243A1

  公开（公告）日：2006-04-13

  The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

  本发明涉及新型苯并咪唑衍生物，含有它们的药物组合物以及它们在治疗由雄激素受体调节的疾病和症状中的应用。
• Novel benzimidazole derivatives useful as selective androgen receptor modulators (SARMS)
  申请人：Ng Raymond

  公开号：US20060111402A1

  公开（公告）日：2006-05-25

  The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

  本发明涉及新型苯并咪唑衍生物、包含它们的药物组合物及其在调节雄激素受体所致的疾病和症状中的应用。
• Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
  申请人：Ng Raymond

  公开号：US20060116412A1

  公开（公告）日：2006-06-01

  The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

  本发明涉及新的苯并咪唑衍生物、包含它们的药物组合物及其在治疗由雄激素受体调节的疾病和症状中的应用。
• Novel Benzimidazole Derivatives Useful as Selective Androgen Receptor Modulators (SARMS)
  申请人：Ng Raymond

  公开号：US20090258909A1

  公开（公告）日：2009-10-15

  The present invention is directed to novel benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

  本发明涉及新型苯并咪唑衍生物，包含它们的制药组合物以及它们在治疗由雄激素受体调节的疾病和症状中的应用。