Thiophene-3-ol, 3-acetate | 88511-89-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: Thiophene-3-ol, 3-acetate
• 英文别名: thiophen-3-yl acetate
• CAS: 88511-89-1
• 化学式: C₆H₆O₂S
• 分子量: 142.18
• InChiKey: XIOIJITYTZVBNC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  54.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  thiophen-3(2H)-one 、 乙酰氯 生成 Thiophene-3-ol, 3-acetate
  参考文献：
  名称：

  HUNTER, GORDON A.;MCNAB, HAMISH, J. CHEM. SOC. CHEM. COMMUN.,(1990) N, C. 375-376

  摘要：

  DOI：

文献信息

• "Growth from surface" Methodology for the Fabrication of Functional Dual Phase Conducting Polymer polypyrrole/polycarbazole/Polythiophene (CP/polyPyr/polyCbz/PolyTh)-Carbon Nanotube (CNT) Composites of Controlled Morphology and Composition - Sidewall versus End-Selective PolyTh Deposition
  申请人：Lellouche Jean-Paul

  公开号：US20130040049A1

  公开（公告）日：2013-02-14

  A “growth from the surface” method for selectively depositing oxidative Liquid Phase Polymerizations (LPPs) onto the carbon nanotube (CNT) surface, said method comprising steps of: a. obtaining Multi-walled Carbon Nanotubes (MWC-NT); b. oxidized said MWCNTs to obtain oxidized COOH-MWCNTs; thereby (a) carboxylative opening oxidation-sensitive end-caps (polyCOOH end cluster); and, (b) introducing defect carboxylic (COOH) groups onto predetermined areas of said oxidized COOH-MWCNTs; c. COOH activating the polyCOOH shell using various COOH activating species; and, d. executing Liquid Phase Polymerization (LPP) oxidative depositing polymers selected from said polyCOOH polyTh-CP polymers, polyCOOH poly-Th-, polyEDOT (PEDOT)-, polyTh polyCOOH poly(thiophenyl-3 acetic acid, thiophenyl-3 acetic acid/EDOT, polyX, wherein X is elected from COOH, OH, NH2, polyCbz/polyPyr CP polymers and related combinatorial mixtures, polyCOOH PEDOT-poly(thiophenyl-3 acetic acid)′ thereby selectively depositing said oxidative LPPs onto said CNT surface.

  一种用于选择性沉积氧化液相聚合物（LPPs）到碳纳米管（CNT）表面的“从表面生长”方法，所述方法包括以下步骤：a. 获得多壁碳纳米管（MWC-NT）；b. 氧化所述MWCNTs以获得氧化的COOH-MWCNTs；从而（a）羧化开启氧化敏感端盖（polyCOOH端簇）；以及（b）在所述氧化的COOH-MWCNTs的预定区域引入缺陷羧基（COOH）基团；c. 使用各种COOH活化物种对polyCOOH壳进行COOH活化；以及d. 执行液相聚合物化学氧化沉积聚合物，所选聚合物来自所述polyCOOH polyTh-CP聚合物，polyCOOH poly-Th-，polyEDOT（PEDOT）-，polyTh polyCOOH poly（噻吩-3 乙酸，噻吩-3 乙酸/EDOT，polyX，其中X选自COOH，OH，NH2，polyCbz/polyPyr CP聚合物和相关组合物，polyCOOH PEDOT-poly（噻吩-3 乙酸）'，从而选择性地将所述氧化LPPs沉积到所述CNT表面。
• [EN] INDOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS<br/>[FR] DÉRIVÉS D'INDOLE COMME ANTAGONISTES DU RÉCEPTEUR CRTH2
  申请人：MERCK FROSST CANADA LTD

  公开号：WO2010031183A1

  公开（公告）日：2010-03-25

  Compound of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.

  化合物I的拼合物是PGD2受体CRTH2的拮抗剂，因此在治疗和/或预防CRTH2介导的疾病如哮喘方面是有用的。
• INDOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS
  申请人：Colucci John

  公开号：US20110172263A1

  公开（公告）日：2011-07-14

  Compound of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma.

  I类化合物是PGD2受体CRTH2的拮抗剂，因此在治疗和/或预防CRTH2介导的疾病，如哮喘方面非常有用。
• NEW AMINOTETRALINE DERIVATIVES
  申请人：Gmeiner Peter

  公开号：US20120277262A1

  公开（公告）日：2012-11-01

  The present application relates to compounds of formula (I): and pharmaceutically acceptable salts and solvates thereof, wherein the substituents are as defined herein, compositions containing such compounds and the uses of such compounds in producing medicaments for the treatment of various diseases and conditions, such as of the central nervous system.

  本申请涉及式(I)的化合物及其药学上可接受的盐和溶剂化合物，其中取代基如此定义，含有这种化合物的组合物以及在制备治疗各种疾病和病症的药物中使用这种化合物的用途，例如中枢神经系统的疾病和病症。
• AMINOTETRALINE DERIVATIVES
  申请人：Gmeiner Peter

  公开号：US20130331429A1

  公开（公告）日：2013-12-12

  The present application relates generally to amino tetraline derivative compounds and methods of use, specifically, embodiments including compounds of formula (I) described herein, pharmaceutically acceptable salts and solvates. More specifically, this application relates to amino tetraline derivative compounds and uses of such compounds producing medicaments for the treatment of various disease and conditions including movement disorders and disorders of the central nervous system.

  本申请涉及氨基四氢萘衍生物化合物及其使用方法，具体包括本文所述的式（I）化合物、药学上可接受的盐和溶剂的实施方式。更具体地说，本申请涉及氨基四氢萘衍生物化合物及其使用，用于制备治疗各种疾病和病症的药物，包括运动障碍和中枢神经系统疾病和病症。