4-Chloro-2-methyl-furan | 85803-78-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 芳基卤化物
• 英文名称: 4-Chloro-2-methyl-furan
• 英文别名: 4-Chloro-2-methylfuran
• CAS: 85803-78-7
• 化学式: C₅H₅ClO
• 分子量: 116.547
• InChiKey: ABEABJVIGVXDKR-UHFFFAOYSA-N

物化性质

• 沸点：
  109.0±20.0 °C(Predicted)
• 密度：
  1.160±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  13.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  chloro-(2-chloro-1-hydroxy-4-oxopent-2-en-3-yl)mercury 、 chloro-(3-chloro-5-hydroxy-5-methyl-2H-furan-4-yl)mercury 、 一氧化碳 、 乙醚 生成 4-Chloro-2-methyl-furan
  参考文献：
  名称：

  LAROCK, R. C.;LIU, CHIH-LING, J. ORG. CHEM., 1983, 48, N 13, 2151-2158

  摘要：

  DOI：

文献信息

• NITROGENOUS HETEROCYCLIC COMPOUNDS WITH INSECTICIDAL ACTIVITY, AND THE PREPARATION AND USE THEREOF
  申请人：Li Zhong

  公开号：US20100298346A1

  公开（公告）日：2010-11-25

  The present invention relates to nitro-containing heterocyclic or ring-opening nitrogenous compounds of formula (A), wherein R 1 , R 2 , R 3 , R 4 , R 5 , Y, Z, and W are as defined in the specification. The present invention discloses the preparation and the uses of a novel insecticide. Said compound and the derivatives thereof have high insecticidal activity to farm insects including homoptera and Lepidoptera pests, such as aphis, fulgorides, aleyrodids, leafhopper, commom thrips, cotton bollworm, cabbage caterpillar, cabbage moth, cotton leafworm, armyworn and so on.

  本发明涉及具有以下结构式（A）的含硝基杂环或开环含氮化合物，其中R1、R2、R3、R4、R5、Y、Z和W如规范中所定义。本发明揭示了一种新型杀虫剂的制备和用途。所述化合物及其衍生物对包括同翅目和鳞翅目害虫在内的农作物害虫具有高杀虫活性，如蚜虫、食蝽、粉虱、叶蝉、普通蓟马、棉铃虫、甘蓝青虫、甘蓝夜蛾、棉叶虫、军蠶等。
• AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20150005348A1

  公开（公告）日：2015-01-01

  An amide compound represented by formula (I) has an excellent pest control effect. (In the formula, Y represents a 3-7 membered saturated heterocyclic ring which contains, as ring-forming components(s), one or more atoms or groups that are selected from the group consisting of an oxygen atom and —S(O) t —, the saturated heterocyclic ring may have one to three atoms or groups selected from group D and t represents 0 or the like; x represents a C 1 -C 8 chain hydrocarbon group having one group that is selected from group A; W represents —CR 8 — or the like; r represents 1 or the like; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 may be the same or different and each represents a hydrogen atom or the like; and n represents 1 or the like.)

  式(I)所代表的酰胺化合物具有出色的杀虫效果。（在该式中，Y代表一个含有3-7个饱和杂环环的结构，该结构中包含一个或多个从氧原子和-S(O)t-组成的原子或基团，饱和杂环环可能有一个到三个从D组成的原子或基团，t代表0或类似物；x代表一个C1-C8链烃基，其中有一个来自A组的基团；W代表-CR8-或类似物；r代表1或类似物；R1、R2、R3、R4、R5、R6、R7和R8可以相同也可以不同，每个代表一个氢原子或类似物；n代表1或类似物。）
• 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase
  申请人：Incyte Corporation

  公开号：US20140315962A1

  公开（公告）日：2014-10-23

  The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives.

  本发明涉及1,2,5-噁二唑衍生物及其组合物，它们是色胺酸2,3-双加氧酶的抑制剂，可用于治疗癌症和其他疾病，并涉及制备这种1,2,5-噁二唑衍生物的过程和中间体。
• METHOD FOR CONTROLLING ARTHROPOD PEST
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20150344466A1

  公开（公告）日：2015-12-03

  An amide compound represented by formula (I): [wherein A represents a 3- to 7-membered saturated heterocyclic ring which contains, as ring-forming component(s), one or more atoms or groups selected from the group consisting of an oxygen atom and —S(O) t —, t represents 0, etc., R 1 and R 2 are the same or different and represent a hydrogen atom, etc., n represents 0, etc., the following formula (II): represents a 5-membered aromatic ring, in which Z represents a nitrogen atom or a carbon atom and X 1 , X 2 and X 3 are the same or different and represent a nitrogen atom, etc., R 3 and R 4 are the same or different and represent a hydrogen atom, etc., m represents 0 to 2, Q represents one group selected from group A or a C1 to C8 chain hydrocarbon group optionally having one group selected from group A, Y represents an oxygen atom, etc., u represents 0, etc., and v represents 0, etc.] has excellent arthropod pest controlling effects.

  化合物式(I)所代表的酰胺化合物：[其中A代表一个3到7个成员的饱和杂环环，该环包含作为环构成组分之一或多个原子或基团，所选自氧原子和—S（O）t—群，t代表0等；R1和R2相同或不同，代表氢原子等；n代表0等；下列式子(II)代表一个5个成员的芳香环，在该环中Z代表一个氮原子或一个碳原子，X1、X2和X3相同或不同，代表氮原子等，R3和R4相同或不同，代表氢原子等，m代表0到2，Q代表从群A中选择的一个群或一个C1到C8链烃基团，该基团可以选择从群A中选择的一个群，Y代表氧原子等，u代表0等，v代表0等]具有优良的节肢动物害虫控制效果。
• 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：EP0303269A2

  公开（公告）日：1989-02-15

  Disclosed is an anti-cancer compound of the formula wherein one of R¹ and R² is an optionally substituted furanyl-lower alkyl or thienyl-lower alkyl group; and the other of R¹ and R² is (i) lower alkanoyl having 1 or 2 substituents selected from a group -NR³R⁴ (wherein R³ and R⁴ each represent hydrogen, lower alkyl, lower alkoxy carbonyl or phenyl-lower alkoxycarbonyl), carboxyl, lower alkylthio, phenyl having hydroxyl or phenyl-lower alkoxy on the phenyl ring and phenyl-lower alkoxycarbonyl, or (ii) a pyrrolidinylcarbonyl optionally having lower alkoxycarbonyl, or a salt thereof.

  公开了一种抗癌化合物，其式如下 其中 R¹ 和 R² 之一是任选取代的呋喃低级烷基或噻吩低级烷基；其中 R³ 和 R⁴ 各自代表氢、低级烷基、低级烷氧基羰基或苯基-低级烷氧基羰基、羧基、低级烷硫基、苯基环上有羟基或苯基低级烷氧基的苯基和苯基低级烷氧基羰基，或 (ii) 可选择具有低级烷氧基羰基的吡咯烷基羰基或其盐。