m-Carboxyphenylmethacrylamid | 28319-08-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: m-Carboxyphenylmethacrylamid
• 英文别名: 3-methacryloylamino-benzoic acid；3-Methacryloylamino-benzoesaeure；N-methacryloyl-m-amino benzoic acid；3-(2-methylprop-2-enoylamino)benzoic acid
• CAS: 28319-08-6
• 化学式: C₁₁H₁₁NO₃
• 分子量: 205.213
• InChiKey: CRWLCUCGUWZZEM-UHFFFAOYSA-N

物化性质

• 熔点：
  200.5-201 °C
• 沸点：
  444.7±37.0 °C(Predicted)
• 密度：
  1.259±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  间氨基苯甲酸 、 甲基丙烯酰氯 在 N,N-二甲基苯胺 作用下， 生成 m-Carboxyphenylmethacrylamid
  参考文献：
  名称：

  Koton et al., Zhurnal Obshchei Khimii, 1957, vol. 27, p. 185,187; engl. Ausg. S. 209, 210

  摘要：

  DOI：

文献信息

• Adhesive composition for dental treatment
  申请人：SUN MEDICAL CO., LTD.

  公开号：EP0684033A1

  公开（公告）日：1995-11-29

  An adhesive composition comprising (A) 98 to 60 parts by weight of a polymerizable monomer mixture containing 2 to 25 % by weight of a monomer having acidic group, (B) 2 to 40 parts by weight of a polymer, preferably a polymer which can form a solution or dispersion having the property that the solution or dispersion of 10 parts by weight of the polymer in 90 parts by weight of methyl methacrylate shows a viscosity of 100 cps or less at 25° C, and (C) 0.01 to 35 parts by weight of a polymerization initiator, provided that the total amount of the components (A), (B) and (C) is 100 parts by weight. According to the present invention, there can be provided an adhesive composition which is easy to handle for the restoration treatment of a tooth, so that adhesion dental treatment can be reliably carried out.

  一种粘合剂组合物，包括(A)98 至 60 份(重量)可聚合单体混合物，其中含有 2 至 25%(重量)具有酸性基团的单体；(B)2 至 40 份(重量)聚合物，最好是可形成溶液或分散体的聚合物，其特性是 10 份(重量)聚合物在 90 份(重量)甲基丙烯酸甲酯中的溶液或分散体在 25°C 时的粘度为 100 cps 或以下；以及(C)0.01至35份（重量）聚合引发剂，条件是组分(A)、(B)和(C)的总量为100份（重量）。 根据本发明，可以提供一种易于处理的粘合剂组合物，用于牙齿的修复治疗，从而可以可靠地进行粘合牙科治疗。
• Dental or surgical adhesive and polymerization initiator composition for the same
  申请人：SUN MEDICAL CO., LTD.

  公开号：EP0758544A2

  公开（公告）日：1997-02-19

  A polymerization initiator composition comprising 100 parts by weight of an organic boron compound (A) and 10 to 150 parts by weight of an aprotic solvent (B) having a boiling point of 30 to 150°C, is useful as an initiator in a dental or surgical adhesive composition.

  聚合引发剂组合物由 100 重量份的有机硼化合物（A）和 10 至 150 重量份的沸点为 30 至 150°C 的无相溶剂（B）组成，可用作牙科或外科粘合剂组合物的引发剂。
• Adhesive composition for dental or surgical treatment
  申请人：SUN MEDICAL CO., LTD.

  公开号：EP0835646A2

  公开（公告）日：1998-04-15

  An adhesive composition for dental or surgical treatment comprising (A) 2 to 24 parts by weight of an organic boron compound, (B) 0.002 to 0.5 part by weight of a photopolymerization initiator, (C) 75 to 97 parts by weight of a polymerizable monomer mixture comprising 2 to 20 % by weight of a monomer containing an acidic group and 80 to 98 % by weight of a monomer containing no acidic group, and (D) optionally, 250 parts or less by weight of a filler. A method for preparing this composition is also disclosed.

  一种用于牙科或外科治疗的粘合剂组合物，其中包括：(A) 2 至 24 份（按重量计）有机硼化合物；(B) 0.002 至 0.5 份（按重量计）光聚合引发剂；(C) 75 至 97 份（按重量计）可聚合单体混合物，其中包括 2 至 20 %（按重量计）含有酸性基团的单体和 80 至 98 %（按重量计）不含酸性基团的单体；以及 (D) 可选的 250 份或更少（按重量计）填料。还公开了制备这种组合物的方法。
• PASTE POLYMERIZATION INITIATOR COMPOSITION, DENTAL OR SURGICAL ADHESIVE AND ADHESIVE KIT
  申请人：SUN MEDICAL CO., LTD.

  公开号：EP1489103A1

  公开（公告）日：2004-12-22

  The present invention is a polymerization initiator paste composition which comprises (A) an organoboron compound which is liquid at 25°C and (B) particles having an average particle diameter of 0.001 to 50 µm and inert to the organoboron compound (A), in an amount of 4 to 400 parts by weight based on 100 parts by weight of the organoboron compound (A), and has a consistency, as measured at 25°C under a load of 300 g in accordance with a method defined in ISO4823, of 15 to 100 mm. This composition constitutes a dental kit or the like together with a polymerizable monomer separately packaged. According to the present invention, an organoboron compound can be used safely, and because the composition is a paste, it is very easily utilized.

  本发明是一种聚合引发剂糊剂组合物，它包括(A)在 25℃时为液态的有机硼化合物和(B)平均粒径为 0.001 至 50 微米且对有机硼化合物(A)惰性的颗粒，以 100 重量份的有机硼化合物(A)为基准，含量为 4 至 400 重量份，并且根据 ISO4823 中规定的方法，在 25℃、载重 300 克的条件下测得的稠度为 15 至 100 毫米。这种组合物与单独包装的可聚合单体一起构成牙科套装或类似产品。根据本发明，可以安全地使用有机硼化合物，而且由于该组合物是糊状的，所以非常容易使用。
• DENTAL OR SURGICAL ADHESIVE AND POLYMERIZATION INITIATOR COMPOSITION THEREFOR
  申请人：SUN MEDICAL CO., LTD.

  公开号：EP1704845A1

  公开（公告）日：2006-09-27

  A polymerization initiator composition which does not burn or ignite even when it contacts paper or the like in air and can provide high polymerization activity to a polymerizable composition to cure it in a short period of time, and an adhesive composition comprising the same. The above polymerization initiator composition comprises 100 parts by weight of (A) an organic boron compound such as a trialkyl boron, alkoxyalkyl boron, dialkyl borane, monocyclo or bicyclo compound having a boron atom as a hetero atom or partially oxidated trialkyl boron, 5 to 40 parts by weight of (B) an aprotic solvent having a boiling point of 50 to 120° C, and 0.2 to 5 parts by weight of (C) an alcohol having a boiling point of 60 to 180°C.

  一种聚合引发剂组合物，即使在空气中接触纸张或类似物也不会燃烧或点燃，并能为可聚合组合物提供较高的聚合活性，使其在短时间内固化，以及由其组成的粘合剂组合物。上述聚合引发剂组合物包括 100 重量份的(A)有机硼化合物，如三烷基硼、烷氧基烷基硼、二烷基硼烷、具有硼原子作为杂原子的单环或双环化合物或部分氧化的三烷基硼；5 至 40 重量份的(B)沸点为 50 至 120℃的烷基溶剂；以及 0.2 至 5 重量份的(C)沸点为 60 至 180℃的醇。