(2R,3R,5R,6R)-2,3-Diallyl-5,6-diphenyl-[1,4]dioxane | 172748-82-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (2R,3R,5R,6R)-2,3-Diallyl-5,6-diphenyl-[1,4]dioxane
• 英文别名: (2R,3R,5R,6R)-2,3-diphenyl-5,6-bis(prop-2-enyl)-1,4-dioxane
• CAS: 172748-82-2
• 化学式: C₂₂H₂₄O₂
• 分子量: 320.431
• InChiKey: IMOHTHOATRVEIR-GXRSIYKFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (2R,3R,5R,6R)-2,3-Diallyl-5,6-diphenyl-[1,4]dioxane 在 palladium dihydroxide 氢气 作用下， 以 乙酸乙酯 为溶剂， 生成 syn-4,5-octanediol
  参考文献：
  名称：

  Asymmetric synthesis using C2-symmetric diols: Use of (5R,6R)-3-acetoxy-5,6-diphenyl-1,4-dioxan-2-one as a chiral synthetic equivalent of 1,2-ethanediol 1,2-dicarbocation

  摘要：

  A new route to chiral diol systems has been developed based on double nucleophilic addition to the cationic ions fixed on a 6-membered ring system using chiral hydrobenzoin as an auxiliary.

  DOI：

  10.1016/0957-4166(95)00278-w
• 作为产物：
  描述：

  氢胺 在 吡啶 、 4-二甲氨基吡啶 、 三氟甲磺酸三甲基硅酯 、 二异丁基氢化铝 、 对甲苯磺酸 作用下， 以 二氯甲烷 、 乙腈 、 苯 为溶剂， 生成 (2R,3R,5R,6R)-2,3-Diallyl-5,6-diphenyl-[1,4]dioxane
  参考文献：
  名称：

  Asymmetric synthesis using C2-symmetric diols: Use of (5R,6R)-3-acetoxy-5,6-diphenyl-1,4-dioxan-2-one as a chiral synthetic equivalent of 1,2-ethanediol 1,2-dicarbocation

  摘要：

  A new route to chiral diol systems has been developed based on double nucleophilic addition to the cationic ions fixed on a 6-membered ring system using chiral hydrobenzoin as an auxiliary.

  DOI：

  10.1016/0957-4166(95)00278-w

文献信息

• Asymmetric synthesis using C2-symmetric diols: Use of (5R,6R)-2,3-diacetoxy-5,6-diphenyl-1,4-dioxane as a chiral synthetic equivalent of 1,2-ethanediol 1,2-dicarbocation
  作者：Hiromichi Fujioka、Hidetoshi Kitagawa、Yasushi Nagatomi、Yasuyuki Kita

  DOI：10.1016/0957-4166(95)00277-v

  日期：1995.9

  A new route to chiral diol systems has been developed based on the double nucleophilic addition to the (5R,6R)-2,3-diacetoxy-5,6-diphenyl-1,4-dioxanes using chiral hydrobenzoin as an auxiliary.
• Asymmetric synthesis using C2-symmetric diols: Use of (5R,6R)-3-acetoxy-5,6-diphenyl-1,4-dioxan-2-one as a chiral synthetic equivalent of 1,2-ethanediol 1,2-dicarbocation
  作者：Hiromichi Fujioka、Naoki Matsunaga、Hidetoshi Kitagawa、Yasushi Nagatomi、Michinori Kondo、Yasuyuki Kita

  DOI：10.1016/0957-4166(95)00278-w

  日期：1995.9

  A new route to chiral diol systems has been developed based on double nucleophilic addition to the cationic ions fixed on a 6-membered ring system using chiral hydrobenzoin as an auxiliary.