pentacyclo[6.6.6.0^2,7.0^9,14.0^15.20]icosa-2,4,6,9,11,13,15,17,19-nonaen-4-ylmethanol | 38157-52-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: pentacyclo[6.6.6.0^2,7.0^9,14.0^15.20]icosa-2,4,6,9,11,13,15,17,19-nonaen-4-ylmethanol
• 英文别名: Triptycen-2-ylmethanol；4-pentacyclo[6.6.6.02,7.09,14.015,20]icosa-2(7),3,5,9,11,13,15,17,19-nonaenylmethanol
• CAS: 38157-52-7
• 化学式: C₂₁H₁₆O
• 分子量: 284.357
• InChiKey: KOIIOGJKXLLREI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  pentacyclo[6.6.6.0^2,7.0^9,14.0^15.20]icosa-2,4,6,9,11,13,15,17,19-nonaen-4-ylmethanol 在 氯化亚砜 作用下， 生成 2-(Chlormethyl)-triptycen
  参考文献：
  名称：

  Skvarchenko,V.R. et al., Journal of Organic Chemistry USSR (English Translation), 1971, vol. 7, p. 2019 - 2021

  摘要：

  DOI：

文献信息

• DEFENSIN-LIKE MOLECULES AS NOVEL ANTIMICROBIAL AGENTS
  申请人：De Leeuw Erik

  公开号：US20130231376A1

  公开（公告）日：2013-09-05

  Disclosed are methods of treating and/or preventing infections in mammals caused by microorganisms, by administering to a mammal a therapeutically effective amount of at least one defensin-like molecule, e.g., in a composition that includes such molecule. Also disclosed are the use of such defensin-like molecules for treating and/or preventing infections in mammals; and kits that may include such molecules, or compositions that include such molecules, as well as instructions for using such molecules to treat a mammal.
• US8796323B2
  申请人：——

  公开号：US8796323B2

  公开（公告）日：2014-08-05