2-Methoxy-6-[4-[2-[4-(3-methoxy-2-oxycyanophenoxy)-3,5-dimethylphenyl]propan-2-yl]-2,6-dimethylphenoxy]benzonitrile oxide | 1221407-37-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Methoxy-6-[4-[2-[4-(3-methoxy-2-oxycyanophenoxy)-3,5-dimethylphenyl]propan-2-yl]-2,6-dimethylphenoxy]benzonitrile oxide
• CAS: 1221407-37-9
• 化学式: C₃₅H₃₄N₂O₆
• 分子量: 578.665
• InChiKey: NKCIGFBHRKYEDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  43
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  98.3
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-Methoxy-6-[4-[2-[4-(3-methoxy-2-oxycyanophenoxy)-3,5-dimethylphenyl]propan-2-yl]-2,6-dimethylphenoxy]benzonitrile oxide 、 以 二氯甲烷 为溶剂， 反应 120.0h， 以60.7 mg的产率得到
  参考文献：
  名称：

  Click Annulation of Pseudo[2]rotaxane to [2]Catenane Exploiting Homoditopic Nitrile N-Oxide

  摘要：

  A mild annulation reaction of a propargyl-terminated pseudorotaxane with a homoditopic stable nitrite N-oxide enabled the efficient synthesis of catenanes consisting of not only dibenzo-24-crown-8-ether (DB24C8) but also dibenzo-30-crown-10-ether (DB30C10) as a wheel component. A dynamic H-1 NMR study showed the highly enhanced mobility of the components of the DB30C10-based[2]catenane due to the enlarged wheel cavity.

  DOI：

  10.1021/ol401986u
• 作为产物：
  描述：

  在 N-氯代丁二酰亚胺 、 三乙胺 作用下， 以 氯仿 为溶剂， 反应 0.33h， 以98%的产率得到2-Methoxy-6-[4-[2-[4-(3-methoxy-2-oxycyanophenoxy)-3,5-dimethylphenyl]propan-2-yl]-2,6-dimethylphenoxy]benzonitrile oxide
  参考文献：
  名称：

  Synthesis of a Kinetically Stabilized Homoditopic NitrileN-Oxide Directed toward Catalyst-free Click Polymerization

  摘要：

  一种动力学稳定的同双齿亚硝基氧化物被制备用于无催化剂点击聚合反应，该反应通过与多种双功能炔烃、烯烃和腈单体的1,3-偶极环加成高效进行。聚合反应得到相应的高分子量和高产率的聚合物。

  DOI：

  10.1246/cl.2010.420

文献信息

• CROSSLINKER, CROSSLINKED POLYMER MATERIAL, AND PRODUCTION METHOD OF THE CROSSLINKED POLYMER MATERIAL
  申请人：SEO Akishige

  公开号：US20110224380A1

  公开（公告）日：2011-09-15

  The present invention provides a crosslinker used for crosslinking a polymer material having, in the molecule thereof, a multiple bond reactable with a nitrile oxide, the crosslinker including a bifunctional nitrile oxide having an aromatic nitrile oxide derivative structure in which one hydrogen atom of an aromatic ring is substituted with a nitrile oxide group and all hydrogen atoms at an ortho-position of the nitrile oxide group are substituted with a substituent other than a nitrile oxide group, wherein two such aromatic nitrile oxide derivative structures are bonded to either two oxy groups of a di-oxy structure having the two oxy groups or two carbonyl groups of a di-carbonyl structure having the two carbonyl groups.
• US8530585B2
  申请人：——

  公开号：US8530585B2

  公开（公告）日：2013-09-10
• Synthesis of a Kinetically Stabilized Homoditopic Nitrile<i>N</i>-Oxide Directed toward Catalyst-free Click Polymerization
  作者：Young-Gi Lee、Morio Yonekawa、Yasuhito Koyama、Toshikazu Takata

  DOI：10.1246/cl.2010.420

  日期：2010.4.5

  A kinetically stabilized homoditopic nitrile N-oxide was prepared for a catalyst-free click polymerization that efficiently proceeded via 1,3-dipolar cycloaddition with several bifunctional alkyne, alkene, and nitrile monomers. The polymerization afforded the corresponding polymers with high molecular weights and yields.

  一种动力学稳定的同双齿亚硝基氧化物被制备用于无催化剂点击聚合反应，该反应通过与多种双功能炔烃、烯烃和腈单体的1,3-偶极环加成高效进行。聚合反应得到相应的高分子量和高产率的聚合物。
• Click Annulation of Pseudo[2]rotaxane to [2]Catenane Exploiting Homoditopic Nitrile <i>N</i>-Oxide
  作者：Tatsuya Yuki、Yasuhito Koyama、Tohru Matsumura、Toshikazu Takata

  DOI：10.1021/ol401986u

  日期：2013.9.6

  A mild annulation reaction of a propargyl-terminated pseudorotaxane with a homoditopic stable nitrite N-oxide enabled the efficient synthesis of catenanes consisting of not only dibenzo-24-crown-8-ether (DB24C8) but also dibenzo-30-crown-10-ether (DB30C10) as a wheel component. A dynamic H-1 NMR study showed the highly enhanced mobility of the components of the DB30C10-based[2]catenane due to the enlarged wheel cavity.