N-(2-chloroethyl)-4-fluoro-aniline | 1211456-85-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(2-chloroethyl)-4-fluoro-aniline
• 英文别名: N-(2-chloroethyl)-4-fluoroaniline
• CAS: 1211456-85-7
• 化学式: C₈H₉ClFN
• 分子量: 173.618
• InChiKey: AXKGBAYRISYPHV-UHFFFAOYSA-N

物化性质

• 沸点：
  263.0±25.0 °C(Predicted)
• 密度：
  1.231±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-(2-chloroethyl)-4-fluoro-aniline 在 盐酸 、 sodium hydroxide 作用下， 以 水 、 二甲基亚砜 为溶剂， 反应 24.0h， 生成 O-[2-(4-fluoroanilino)ethyl]hydroxylamine
  参考文献：
  名称：

  IMIDAZO[1,2-A]PYRIDINE DERIVATIVES

  摘要：

  The current invention relates to compounds of the formula (I), wherein the substituents are as defined in claim 1, to processes and methods for preparing compounds of formula (I), to agrochemical compositions comprising compounds of formula (I) as defined in claim 1, to preparation of these compositions and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling infestation of plants, harvested food crops, seeds or non-living materials by phytopathogenic microorganisms, in particular fungi.

  公开号：

  WO2024126404A1
• 作为产物：
  描述：

  4-氟苯胺 、 氯乙醛 在 甲醇 、 sodium cyanoborohydride 、 溶剂黄146 作用下， 生成 N-(2-chloroethyl)-4-fluoro-aniline
  参考文献：
  名称：

  IMIDAZO[1,2-A]PYRIDINE DERIVATIVES

  摘要：

  The current invention relates to compounds of the formula (I), wherein the substituents are as defined in claim 1, to processes and methods for preparing compounds of formula (I), to agrochemical compositions comprising compounds of formula (I) as defined in claim 1, to preparation of these compositions and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling infestation of plants, harvested food crops, seeds or non-living materials by phytopathogenic microorganisms, in particular fungi.

  公开号：

  WO2024126404A1

文献信息

• MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS
  申请人：Nishida Hidemitsu

  公开号：US20110059958A1

  公开（公告）日：2011-03-10

  The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.

  本发明提供了如下式（I）所描述的化合物，或其药学上可接受的盐或溶剂。本发明还提供了包含一种或多种所述化合物的制药组合物，并使用该化合物治疗或预防血栓、栓塞、高凝状态或纤维化变化的方法。
• US8642582B2
  申请人：——

  公开号：US8642582B2

  公开（公告）日：2014-02-04
• US8987242B2
  申请人：——

  公开号：US8987242B2

  公开（公告）日：2015-03-24